Oral cannabidiol does not produce a signal for abuse liability in frequent marijuana smokers.

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“Cannabidiol (CBD) is a naturally occurring constituent of the marijuana plant.

In the past few years, there has been great interest in the therapeutic effects of isolated CBD and it is currently being explored for numerous disease conditions (e.g., pain, epilepsy, cancer, various drug dependencies). However, CBD remains a Schedule I drug on the U.S. Controlled Substances Act (CSA).

Despite its status, there are no well-controlled data available regarding its abuse liability.

Overall, CBD did not display any signals of abuse liability at the doses tested and these data may help inform U.S. regulatory decisions regarding CBD schedule on the CSA.”

https://www.ncbi.nlm.nih.gov/pubmed/28088032

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