“One of the oldest pharmacological remedies for nausea and vomiting is the plant cannabis…
Cannabis has long been known to limit or prevent nausea and vomiting from a variety of causes.
This has led to extensive investigations that have revealed an important role for cannabinoids and their receptors in the regulation of nausea and emesis.
With the discovery of the endocannabinoid system, novel ways to regulate both nausea and vomiting have been discovered that involve the production of endogenous cannabinoids acting centrally.
Here we review recent progress in understanding the regulation of nausea and vomiting by cannabinoids and the endocannabinoid system, and we discuss the potential to utilize the endocannabinoid system in the treatment of these frequently debilitating conditions…
Nausea and vomiting are frequently debilitating conditions that require substantial effort and cost to manage.
Advances in recent progress in understanding the regulation of nausea and vomiting by cannabinoids and the endocannabinoid system have revealed significant potential for therapeutic approaches to be developed.”