“The aim of the present article is to review the cardioprotective properties of cannabinoids, with an emphasis on the signaling pathways involved.

Cannabinoids have been reported to protect against ischemia in rat isolated hearts, as well as in rats and mice in vivo.

Finally, although nitric oxide (NO) was shown to exert both pro and anti-apoptotic effects on cardiomyocytes, with an apparently controversial effect on myocardial survival, our data suggest that NO may contribute to the cardioprotective effect of some cannabinoids.”

“Signaling pathways involved in the cardioprotective effects of cannabinoids.”  http://www.ncbi.nlm.nih.gov/pubmed/17031075

https://www.jstage.jst.go.jp/article/jphs/102/2/102_2_155/_article