Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats.

“To test if urodynamic effects from systemic Fatty Acid Amide Hydrolase (FAAH) inhibition involve sacral spinal cannabinoid type 1 (CB1) or type 2 (CB2) receptors…

Urodynamic effects of systemic FAAH inhibition involve activities at spinal neuronal CB1 and CB2 receptors in normal and obstructed rats.

Endogenous spinal CB receptor ligands seem to regulate normal micturition and bladder overactivity (BO). Altered spinal CB receptor functions may be involved in the pathogenesis of obstruction-induced BO.”

http://www.ncbi.nlm.nih.gov/pubmed/25788026

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