Cannabis derivatives therapy for a seronegative stiff-person syndrome: a case report

“Stiff-person syndrome (SPS) is an uncommon and disabling disorder… Cannabis derivatives [tetrahydrocannabinol (THC) and cannabidiol (CBD)] are available as an oromucosal spray (Sativex(®)… Our objective is to report a case of seronegative SPS successfully treated with THC-CBD oromucosal spray… THC-CBC can be an option for SPS patient. Our case report suggests that THC-CBD oromucosal spray is an alternative treatment for patients with refractory SPS…”

http://www.ncbi.nlm.nih.gov/pubmed/22726074