Tag Archives: treatment

Extremely low doses of THC protect the brain from long-term cognitive damage

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“Conditioning the brain. Extremely low doses of marijuana’s psychoactive component protect brain before and after injury, says Tel Aviv University researcher.

While performing experiments on the biology of cannabis, Prof. Sarne and his fellow researchers discovered that low doses of the drug had a big impact on cell signalling, preventing cell death and promoting growth factors. This finding led to a series of experiments designed to test the neuroprotective ability of THC in response to various brain injuries.

In the lab, the researchers injected mice with a single low dose of THC either before or after exposing them to brain trauma. A control group of mice sustained brain injury but did not receive the THC treatment. When the mice were examined 3 to 7 weeks after initial injury, recipients of the THC treatment performed better in behavioral tests measuring learning and memory. Additionally, biochemical studies showed heightened amounts of neuroprotective chemicals in the treatment group compared to the control group.”

More: http://www.news-medical.net/news/20130531/Extremely-low-doses-of-THC-protect-the-brain-from-long-term-cognitive-damage.aspx

Marijuana component can halt brain damage

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“Extremely low doses of THC, the psychoactive component of marijuana, protects the brain from long-term cognitive damage in case of injury from hypoxia (lack of oxygen), seizures, or toxic drugs, a new study has claimed.

Medical cannabis is often used by sufferers of chronic ailments, including cancer and post-traumatic stress disorder, to combat pain, insomnia, lack of appetite, and other symptoms.

Now, Professor Yosef Sarne of Tel Aviv University’s Adelson Center for the Biology of Addictive Diseases at the Sackler Faculty of Medicine in US found the drug has neuroprotective qualities as well.

Previous studies focused on injecting high doses of THC within a very short time frame approximately 30 minutes before or after injury.

Sarne’s current research, published in the journals Behavioural Brain Research and Experimental Brain Research, demonstrates that even extremely low doses of THC around 1,000 to 10,000 times less than that in a conventional marijuana cigarette administered over a wide window of 1 to 7 days before or 1 to 3 days after injury can jump start biochemical processes which protect brain cells and preserve cognitive function over time.

This treatment, especially in light of the long time frame for administration and the low dosage, could be applicable to many cases of brain injury and be safer over time, Sarne said.

While performing experiments on the biology of cannabis, researchers found that low doses of the drug had a big impact on cell signalling, preventing cell death and promoting growth factors.

This finding led to a series of experiments designed to test the neuroprotective ability of THC in response to various brain injuries.

In the lab, the researchers injected mice with a single low dose of THC either before or after exposing them to brain trauma. A control group of mice sustained brain injury but did not receive the THC treatment.”

http://www.indianexpress.com/news/marijuana-component-can-halt-brain-damage/1123274/

Low doses of marijuana component can protect brain against injury

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Low doses of marijuana component can protect brain against injury

 

 

 

 

 

 

“Though marijuana is a well-known recreational drug, extensive scientific research has been conducted on the therapeutic properties of marijuana in the last decade. Medical cannabis is often used by sufferers of chronic ailments, including cancer and post-traumatic stress disorder, to combat pain, insomnia, lack of appetite, and other symptoms.

Now Prof. Yosef Sarne of Tel Aviv University’s Adelson Center for the Biology of Addictive Diseases at the Sackler Faculty of Medicine says that the drug has neuroprotective qualities as well. He has found that extremely low doses of THC—the psychoactive component of marijuana—protects the brain from long-term cognitive damage in the wake of injury from hypoxia (lack of oxygen), seizures, or toxic drugs. Brain damage can have consequences ranging from mild cognitive deficits to severe neurological damage.

Previous studies focused on injecting high doses of THC within a very short time frame—approximately 30 minutes—before or after injury. Prof. Sarne’s current research, published in the journals Behavioural Brain Research and Experimental Brain Research, demonstrates that even extremely low doses of THC—around 1,000 to 10,000 times less than that in a conventional marijuana cigarette—administered over a wide window of 1 to 7 days before or 1 to 3 days after injury can jumpstart biochemical processes which protect brain cells and preserve cognitive function over time.

This treatment, especially in light of the long time frame for administration and the low dosage, could be applicable to many cases of brain injury and be safer over time…”

More: http://medicalxpress.com/news/2013-05-doses-marijuana-component-brain-injury.html

Marijuana’s THC Can Halt Brain Damage

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Cannabis. Image: Hupu2, Wikimedia

“Though marijuana is a well-known recreational drug, extensive scientific research has been conducted on the therapeutic properties of marijuana in the last decade. Medical cannabis is often used by sufferers of chronic ailments, including cancer and post-traumatic stress disorder, to combat pain, insomnia, lack of appetite and other symptoms.

Now Prof. Yosef Sarne of Tel Aviv Univ.’s Adelson Center for the Biology of Addictive Diseases at the Sackler Faculty of Medicine says that the drug has neuroprotective qualities as well. He has found that extremely low doses of THC — the psychoactive component of marijuana — protects the brain from long-term cognitive damage in the wake of injury from hypoxia (lack of oxygen), seizures or toxic drugs. Brain damage can have consequences ranging from mild cognitive deficits to severe neurological damage.

Previous studies focused on injecting high doses of THC within a very short time frame — approximately 30 minutes — before or after injury. Sarne’s current research, published in the journals Behavioural Brain Research and Experimental Brain Research, demonstrates that even extremely low doses of THC — around 1,000 to 10,000 times less than that in a conventional marijuana cigarette — administered over a wide window of one to seven days before or one to three days after injury can jumpstart biochemical processes which protect brain cells and preserve cognitive function over time.

This treatment, especially in light of the long time frame for administration and the low dosage, could be applicable to many cases of brain injury and be safer over time, Sarne says.”

More: http://www.laboratoryequipment.com/news/2013/05/marijuanas-thc-can-halt-brain-damage

Is marijuana bad for you?

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“Hasn’t pot always been considered harmful?
Not at all. Marijuana, the dried form of the plant Cannabis sativa, was used as an herbal remedy for centuries in China, the Middle East, and Asia. William O’Shaughnessy, a physician for the East India Tea Company, brought it west in the 1830s as a treatment for rheumatism, tetanus, and rabies. It was commonly prescribed as a pain reliever in the U.S. until the 1930s, when its growing popularity caused such concern that the newly founded Federal Bureau of Narcotics reclassified it as a narcotic. The bureau soon launched a decidedly unscientific campaign claiming that marijuana use provoked insanity, homicidal tendencies, and uncontrollable lust. The marijuana user, the bureau asserted, “becomes a fiend with savage or ‘caveman’ tendencies. His sex desires are aroused, and some of the most horrible crimes result.””

Adolescents who smoked marijuana at least four times a week, lost an average of 8 IQ points between the ages of 13 and 38, according to a study from New Zealand.

“Was there any evidence for such claims?
None; in fact, the American Medical Association argued against marijuana prohibition in the 1930s, citing its therapeutic potential. But the bureau made its case that marijuana was “dangerous for the mind and the body,” and the federal government outlawed its use in 1937. It wasn’t until the 1970s that a campaign began to restore marijuana’s therapeutic reputation, and in 1996 California became the first state to legalize cannabis for medicinal purposes. Psychiatrist Tod Mikuriya, a founding father in the medical marijuana movement, claimed that cannabis has none of the adverse side effects of opiates. “In fact,” he said, “it really enhances both quality of life and rehabilitation.””

More: http://theweek.com/article/index/236671/is-marijuana-bad-for-you

Cannabinoids Attenuate Cancer Pain and Proliferation in a Mouse Model

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“Oral cancer represents 3% of all cancers and its overall survival rate of 50% places it among the worst of all cancers

For many years cannabinoids have been used for medicinal and recreational purposes.

Recently, studies have focused on the therapeutic effects of cannabinoids on different cancers. The current study was the first to investigate the therapeutic effects of synthetic cannabinoids on oral cancer.

We investigated the effects of cannabinoid receptor agonists on (1) oral cancer cell viability in vitro and (2) oral cancer pain and tumor growth in a mouse cancer model.

Here we demonstrate the anti-nociceptive and anti-proliferative effects of systemic administration of cannabinoid receptor agonists on human oral cancer cells.

Our results suggest that systemic administration of cannabinoids decease oral cancer pain.

Our findings suggest a direct role for cannabinoid mechanisms in oral cancer pain and proliferation.

The systemic administration of cannabinoid receptor agonists may have important therapeutic implications wherein cannabinoid receptor agonists may reduce morbidity and mortality of oral cancer.

The present findings suggest that cannabinoid treatment may be a promising alternative therapy for oral cancer pain management. Furthermore, CBr2 agonism is not only palliative, but it may also be effective in inhibiting oral cancer growth, making the agonist a particularly desirable therapeutic agent.”

Full Text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099480/

Medical Marijuana Encouraged For Pets Battling Cancer

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“A veterinarian in Southern California is pushing the idea to help pets with cancer fight pain or regain their appetite by giving them pot.

Medical marijuana supporters argue that pot helps reduce chronic pain and nausea. Veterinarian Dr. Douglas Kramer of VetGuru.com said over the years, he’s talked to hundreds of people who’ve given pot to their pets.

“Medical marijuana might have a therapeutic benefit to help animals, especially those with terminal conditions,” Kramer said. “It’s quite clear that people are using it and it has both good an bad effects and they need to discuss it openly with their vet.”

Kramer is pushing for more research and discussion. And, his idea is starting to get traction. Time Magazine and Mother Jones recently explored the controversial issue.

“If people are thinking to take their own medical marijuana and give it to their dogs in a non-controlled dose, the risk of intoxication is too risky to advocate for that,” UC Davis Veterinary Medical Hospital Dr. Karl Jandrey said.

The American Veterinary Medical Association said more research into the effects of marijuana on animals needs to be done before proceeding with treatment since not all drugs affect humans and animals in the same way.”

http://www.digtriad.com/news/watercooler/article/284229/176/Medical-Marijuana-Isnt-Just-For-Humans

Evidence: Cannabinoid Therapy Reduces Breast Cancer Tumors

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“Warning: Many alternative treatments are shams with zero proof. Most alternatives make claims that are not backed up by any evidence or hard empirical medical studies, are are not peer-reviewed. 
 
Peer review means your study and its claims will be vetted by a panel of the best doctors and other medical professionals in that field, for critical review. They will try to find fault in its methodology before publication and its recommendations for possible human treatment.
 
For any cannabis-based study strong enough to stand up to this critical review, and for it to be published in a major journal within such a field as cancer research, is incredible. That’s exactly how strong the evidence for cannabis medicine is starting to become.
 
Imagine that. This plant, this “great friend of humanity” which has helped us survive by giving early humans food, fuel, fiber and medicine, and who ancient healers wrote about in 6000 B.C., more than 8,000 years ago, is now coming back to prove itself and to help save us again.
 
And this time we are starting to find the evidence to back up the claims made for this plant over the centuries…”
 

Tommy Chong is cancer-free

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“Comedian and stoner icon TOMMY CHONG is celebrating after he was declared cancer-free. The Cheech & Chong star revealed last June (12) that he was suffering with stage one prostate cancer, but he decided against traditional medicine to treat the disease and instead opted to overhaul his diet and lifestyle.”

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 “Chong has now told fans he has overcome the cancer, and opened up about how he treated the condition.

In a blog post on CelebStoner.com, he writes, “After I came out with the news last June that a cancer doctor told me I had prostrate cancer and suggested a high frequency treatment that is not approved in America and could only be done in Mexico at the cost of $25,000, I immediately looked at alternatives. I contacted my nephew in Vancouver, who was about to become a doctor, and he suggested I meet with a Dr. McKinnon in Victoria, BC (British Columbia).

“That doctor changed my diet and put me on supplements, and within a year I brought my PSA (Prostate-Specific Antigen) numbers down drastically and eliminated the cancer threat. I also treated the condition with hemp oil (hash oil). With the diet, the supplements and the hash oil, plus a session with a world-renowned healer, Adam Dreamhealer, I’m cancer-free. That’s right, I kicked cancer’s a**! So the magic plant does cure cancer with the right diet and supplements. I’m due for another blood test, MRI, etc., but I feel the best I’ve felt in years.””

http://www.wptv.com/dpp/entertainment/celebrity/Tommy-Chong-is-cancerfree_42071723

Tommy Chong: ‘I’m Cancer-Free!’

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Tommy Chong

“After I came out with the news last June that a cancer doctor told me I had prostrate cancer and suggested a high frequency treatment that is not approved in America and could only be done in Mexico at the cost of $25,000, I immediately looked at alternatives.

 I contacted my nephew in Vancouver, who was about to become a doctor, and he suggested I meet with a Dr. McKinnon in Victoria, BC. That doctor changed my diet and put me on supplements, and within a year I brought my PSA numbers down drastically and eliminated the cancer threat.

I also treated the condition with hemp oil (hash oil). With the diet, the supplements and the hash oil, plus a session with a world-renowned healer, Adam Dreamhealer, I’m cancer-free.

That’s right, I kicked cancer’s ass!

So the magic plant does cure cancer with the right diet and supplements. I’m due for another blood test, MRI, etc., but I feel the best I’ve felt in years. And now for a celebration joint of the finest Kush…”

http://www.celebstoner.com/blogs/tommy-chong/2013/05/06/tommy-chong-im-cancer-free!/