“Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently induce HIV-associated neuropathic pain (HIV-NP).
Smoked cannabis has been reported to improve pain measures in patients with neuropathic pain.
Two clinical trials demonstrated greater efficacy of smoked cannabis over placebo in alleviating HIV-NP.
The available preclinical results suggest that targeting the ECS for prevention and treatment of HIV-NP is a plausible therapeutic option.
Clinical evidence shows that smoked cannabis alleviates HIV-NP.”
“Smoked cannabis has been shown to be effective for managing HIV-NP in two RCTs.”
https://www.sciencedirect.com/science/article/pii/S2667242121000051?via%3Dihub