“Stiff-person syndrome (SPS) is an uncommon and disabling disorder characterised by progressive rigidity and episodic painful spasms involving axial and limb musculature.
The authors report a patient with seronegative SPS successfully treated with THC-CBD oromucosal spray.
In conclusion cannabinoids can be a therapeutic option to treat spasticity associated with neurological diseases such as stiff-person syndrome.
Our patient’s quality of life has improved remarkably although more information is needed about this particular use.”