“To investigate the effect of metabolic syndrome on the bladder cannabinoid receptors 1 and 2 (CB1/CB2) expression and function in the fructose-fed rats (FR).

CONCLUSION:

CB1/CB2 receptors mediate rat bladder relaxation through the PKA and K_ATP pathway. The CB1 receptor may play a more prominent role. The response is decreased in the FR bladder due to reduced expressions of the cannabinoid receptors.” https://www.ncbi.nlm.nih.gov/pubmed/28386998]]>