“To investigate the effect of Hemp seed soft capsule (HSCC) on colonic ion transport and its related mechanisms in constipation rats.

CONCLUSION:

HSSC ameliorates constipation by increasing colonic secretion, which is mediated via the coaction of cAMP-dependent and Ca²⁺-dependent Cl^– channels, NKCC, Na⁺-HCO₃^– cotransporter or Cl^–/HCO₃^– exchanger.” https://www.ncbi.nlm.nih.gov/pubmed/29204056 https://www.wjgnet.com/1007-9327/full/v23/i42/7563.htm