Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors.

“Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors… This study suggests that CB1 receptors located on Sim1-expressing neurons exert a tonic control on locomotor reactivity, unconditioned anxiety, and cued-fear expression under basal conditions as well as after acute or repeated stress.”

http://www.ncbi.nlm.nih.gov/pubmed/21920410

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