Research Progress on the Mechanism of the Antitumor Effects of Cannabidiol

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“Cannabidiol (CBD), a non-psychoactive ingredient extracted from the hemp plant, has shown therapeutic effects in a variety of diseases, including anxiety, nervous system disorders, inflammation, and tumors. CBD can exert its antitumor effect by regulating the cell cycle, inducing tumor cell apoptosis and autophagy, and inhibiting tumor cell invasion, migration, and angiogenesis. This article reviews the proposed antitumor mechanisms of CBD, aiming to provide references for the clinical treatment of tumor diseases and the rational use of CBD.”

“The antitumor effects of CBD in different types of cancer have attracted widespread attention, and the number of relevant research results is steadily increasing. The studies published to date all point to the obvious antitumor effects of CBD and that its mechanisms include the induction of cell cycle arrest and autophagy, the promotion of apoptosis, the modulation of angiogenesis, and the inhibition of tumor cell migration and invasion. In addition, CBD has good synergistic effects with other medicines, and several clinical reports show CBD being used to treat cancer. The results presented in this review indicate that CBD has extremely promising potential for clinical use in the treatment of cancer patients.”

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