Anticancer and immunomodulating effects of Hericium erinaceus (Lion’s Mane) Yamabushitake mushrooms

“Hericium erinaceus (Lion’s Mane) mushroom extracts inhibit metastasis of cancer… edible mushrooms have the potential to serve as a health-promoting functional food.”

“Antimetastatic and immunomodulating effect of water extracts from various mushrooms.”

“[Immunological study on the antitumor effects of fungus polysaccharides compounds]”

“Antitumor and immunoenhancing activities of polysaccharide from culture broth of Hericium spp. The fruiting body and culture broth of many edible mushrooms contain water-soluble polysaccharides. Numerous researchers have reported that these polysaccharides have immunoenhancing effects. In this study,”

“It has been demonstrated that the Hericium erinaceus (HE) mushroom, which primarily consists of polysaccharides, possesses anti-tumor activities…These findings suggest that HE… serves as an effective tool for treating drug-resistant human hepatocellular carcinoma.”

Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells. Phytochemicals in some foods are a potential source of bioactive safe compounds for cancer chemoprevention and suppression of tumor initiation, promotion, and metastasis… we evaluated… Hericium erinaceus (Yamabushitake, Lion’s Mane) mushrooms for their ability to induce apoptosis (programmed cell death) in human leukemia cells…The results indicate that H. erinaceus mushrooms may have therapeutic potential against human leukemia.”

Composition and mechanism of antitumor effects of Hericium erinaceus mushroom extracts in tumor-bearing mice.”

“Potential activity of aqueous extract of culinary-medicinal Lion’s Mane mushroom, Hericium erinaceus (Bull.: Fr.) Pers. (Aphyllophoromycetideae) in accelerating wound healing…”

“Neuroregenerative potential of lion’s mane mushroom, Hericium erinaceus…”

“Hericium erinaceus: an edible mushroom with medicinal values…anti-cancer, immuno-modulating, hypolipidemic, antioxidant and neuro-protective activities of this mushroom. H. erinaceus has also been reported to have anti-microbial, anti-hypertensive, anti-diabetic, wound healing properties among other therapeutic potentials.”

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