“Pinene (or α-pinene) is an aromatic compound commonly found in cannabis that smells a lot like – you guessed it – a forest of pine trees.” http://www.leafly.com/news/cannabis-101/what-is-pinene-and-what-are-the-benefits-of-this-cannabis-terpene
“Anti-inflammatory and chondroprotective activity of (+)-α-pinene: structural and enantiomeric selectivity. Previous studies have suggested that α-pinene, a common volatile plant metabolite, may have anti-inflammatory effects in human chondrocytes, thus exhibiting potential antiosteoarthritic activity… The data obtained show isomer- and enantiomer-selective anti-inflammatory and anticatabolic effects of α-pinene in human chondrocytes, (+)-α-pinene being the most promising for further studies to determine its potential value as an antiosteoarthritic drug.” http://www.ncbi.nlm.nih.gov/pubmed/24455984
“The therapeutic efficacy of α-pinene in an experimental mouse model of allergic rhinitis. In the present study, the therapeutic effect and underlying mechanism of α-pinene (α-PN) in the ovalbumin (OVA)-sensitized allergic rhinitis (AR) model were investigated… Taken together, we suggest that α-PN is a promising anti-allergic agent and may be useful in the clinical management of AR.” http://www.ncbi.nlm.nih.gov/pubmed/25242385
“Structural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6… (+)-α-Pinene is a monoterpene hydrocarbon that is widely distributed in the environment and a potent P450 2B inhibitor. “ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754432/
“Inhibitory effects of α-pinene on hepatoma carcinoma cell proliferation… Taken together, these findings indicate that α-pinene may be useful as a potential anti-tumor drug.” http://www.ncbi.nlm.nih.gov/pubmed/24815485
“Synergistic Antitumor Effect of α-pinene and β-pinene with Paclitaxel against Non-small-cell Lung Carcinoma (NSCLC).” http://www.ncbi.nlm.nih.gov/pubmed/25188609
“Biological activities of α-pinene and β-pinene enantiomers. The antimicrobial activities of the isomers and enantiomers of pinene were evaluated against bacterial and fungal cells.” http://www.ncbi.nlm.nih.gov/pubmed/23442885
“Microbial Synthesis of Pinene” http://pubs.acs.org/doi/abs/10.1021/sb4001382
“Effect of alpha-pinene on nuclear translocation of NF-kappa B in THP-1 cells.” http://www.ncbi.nlm.nih.gov/pubmed/15066217
“Protective effects of alpha-pinene in mice with cerulein-induced acute pancreatitis. Acute pancreatitis (AP) is a complicated inflammatory disease that has an unknown underlying pathogenesis. Because alpha-pinene can modulate inflammation, we examined whether alpha-pinene plays a role in AP… These findings suggest that alpha-pinene has an anti-inflammatory effect during cerulein-induced AP.” http://www.ncbi.nlm.nih.gov/pubmed/22982349