Cannabinoids suppress acute and anticipatory nausea in pre-clinical rat models of conditioned gaping.

“The sensation of nausea is one of the most debilitating human experiences. Current anti-emetic therapies are effective in reducing vomiting, but are less effective in reducing acute and delayed nausea and are completely ineffective in reducing anticipatory nausea.

Recent pre-clinical evidence using a selective rat model of nausea (conditioned gaping reactions) has revealed that┬ácannabinoids┬áhave great promise as treatments for nausea and that their anti-nausea effects may be mediated by the interoceptive insular cortex.”

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