Prevention of carcinogenesis by tea polyphenols – Science

Green Tea
 

“Prevention of carcinogenesis by tea polyphenols… Tea has been considered a medicine and healthful beverage for ages. The beneficial effects of tea are thought to be due to its polyphenolic components….Tea is one of the few chemopreventive agents known to have protective effects at different stages of the carcinogenic process….” http://www.ncbi.nlm.nih.gov/pubmed/11768768

“Tea and tea polyphenols in cancer prevention… The inhibitory action of tea (Camellia sinensis) and tea components against cancer formation has been demonstrated in different animal models involving different organ sites in many laboratories… tea polyphenols affect signal transduction pathways, inhibit cell proliferation and induce apoptosis,”  http://www.ncbi.nlm.nih.gov/pubmed/10721932

“Polyphenols as cancer chemopreventive agents.” http://www.ncbi.nlm.nih.gov/pubmed/8538195

“Mechanisms of inhibition of carcinogenesis by tea.” http://www.ncbi.nlm.nih.gov/pubmed/11237203

“Antioxidative and anti-carcinogenic activities of tea polyphenols” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820244/ 

“Cancer chemopreventive activity and bioavailability of tea and tea polyphenols… Consumption of tea has been associated with many health benefits including the prevention of cancer.” http://www.ncbi.nlm.nih.gov/pubmed/12628518

“Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.” http://www.ncbi.nlm.nih.gov/pubmed/23530632

“Cancer chemoprevention by tea polyphenols… Tea is one of the most widely consumed beverages, second only to water… inhibitory effects of tea against carcinogenesis… tea polyphenols function as cancer chemopreventive agents” http://www.ncbi.nlm.nih.gov/pubmed/10786933

“Tea antioxidants in cancer chemoprevention… properties of tea polyphenols make them effective chemopreventive agents against the initiation, promotion, and progression stages of multistage carcinogenesis.”  http://www.ncbi.nlm.nih.gov/pubmed/9591194 

“Chemopreventive potential of flavonoids in oral squamous cell carcinoma in human studies… These flavonoids, abundant in green tea and black raspberries, respectively, represent promising chemopreventive agents in human oral cancer.”  http://www.ncbi.nlm.nih.gov/pubmed/23857227 

Cancer prevention by tea: Evidence from laboratory studies… The cancer preventive activities of tea (Camellia sinensis Theaceae) have been studied extensively. Inhibition of tumorigenesis by green tea extracts and tea polyphenols has been demonstrated in different animal models, including those for cancers of the skin, lung, oral cavity, esophagus, stomach, small intestine, colon, bladder, liver, pancreas, prostate, and mammary glands.” http://www.ncbi.nlm.nih.gov/pubmed/21397027

“Comparative antimutagenic and anticancer activity of three fractions of black tea polyphenols thearubigins.” http://www.ncbi.nlm.nih.gov/pubmed/21919645

“Hepatoprotective and antioxidant activity of standardized herbal extracts.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371432/

“[Anti-inflammatory effects of tea-flavonoids]… Tea flavonoids belong to the large group of polyphenols and display antioxidative, anti-inflammatory and anti-neoplastic activities… Dietary supplementation with specific tea-flavonoids… could ultimately lead to inhibition of carcinogenesis.” http://www.ncbi.nlm.nih.gov/pubmed/23233307

“Tea and health: Studies in humans.” http://www.ncbi.nlm.nih.gov/pubmed/23448443

“Prevention of chronic diseases by tea: possible mechanisms and human relevance.”  http://www.ncbi.nlm.nih.gov/pubmed/23642203

“Active extracts of black tea (Camellia Sinensis) induce apoptosis of PC-3 prostate cancer cells via mitochondrial dysfunction… Many studies have shown that black tea reduces the risk of several types of cancer… these findings suggest that black tea could act as an effective anti-proliferative agent…” http://www.ncbi.nlm.nih.gov/pubmed/23715786

“Epicatechins Purified from Green Tea (Camellia sinensis) Differentially Suppress Growth of Gender-Dependent Human Cancer Cell Lines.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475929/

“Effects of green tea, black tea, and coffee consumption on the risk of esophageal cancer: a systematic review and meta-analysis of observational studies.” http://www.ncbi.nlm.nih.gov/pubmed/23368908

“Protective effect of green tea on the risks of chronic gastritis and stomach cancer.” http://www.ncbi.nlm.nih.gov/pubmed/11304697

“The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946098/

“Growth inhibition of Walker carcinosarcoma 256 with alcoholic extract of green tea leaves (Camellia sinensis).” http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900008&lng=en&nrm=iso&tlng=en

“Health-promoting effects of green tea… anti-cancer, anti-obesity, anti-atherosclerotic, anti-diabetic, anti-bacterial, and anti-viral…” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365247/

“Meta-analysis of Green Tea Drinking and the Prevalence of Gynecological Tumors in Women… Our analysis indicates that drinking green tea can significantly decrease the risk of ovarian cancer.” http://www.ncbi.nlm.nih.gov/pubmed/23858521

“Polyphenols in brewed green tea inhibit prostate tumor xenograft growth by localizing to the tumor and decreasing oxidative stress and angiogenesis… administration of green tea (GT) extracts in drinking water can inhibit tumor growth…” http://www.ncbi.nlm.nih.gov/pubmed/22405694

“Medicinal benefits of green tea: Part I. Review of noncancer health benefits.” http://www.ncbi.nlm.nih.gov/pubmed/15992239

“Medicinal benefits of green tea: part II. review of anticancer properties.” http://www.ncbi.nlm.nih.gov/pubmed/16131288

“Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer.” http://www.ncbi.nlm.nih.gov/pubmed/10559550

“Green tea (Camellia sinensis) and cancer prevention: a systematic review of randomized trials and epidemiological studies” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577676/

“Green tea (Camellia sinensis) for the prevention of cancer.” http://www.ncbi.nlm.nih.gov/pubmed/19588362

“Green tea prevents non-melanoma skin cancer by enhancing DNA repair.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077767/

“Green tea inhibits cycolooxygenase-2 in non-small cell lung cancer cells through the induction of Annexin-1.” http://www.ncbi.nlm.nih.gov/pubmed/23036202

“Green tea for ovarian cancer prevention and treatment: a systematic review of the in vitro, in vivo and epidemiological studies.” http://www.ncbi.nlm.nih.gov/pubmed/22564714

“Green tea: an effective synergist with anticancer drugs for tertiary cancer prevention.” http://www.ncbi.nlm.nih.gov/pubmed/22626556

“Medicinal Cannabis Does Not Influence the Clinical Pharmacokinetics of Irinotecan and Docetaxel… Coadministration of medicinal cannabis, as herbal tea, in cancer patients treated with irinotecan or docetaxel does not significantly influence the plasma pharmacokinetics of these drugs… medicinal cannabis can be administered concomitantly with both anticancer agents without dose adjustments.”  http://theoncologist.alphamedpress.org/content/12/3/291.long

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