Small animal PET imaging of the type 1 cannabinoid receptor in a rodent model for anorexia nervosa.

“Several lines of evidence strongly implicate a dysfunctional endocannabinoid system (ECS) in eating disorders…


These data point to a widespread transient disturbance of the endocannabinoid transmission, specifically for CB1 receptors in the ABA model. Our data also suggest (1) gender effects on regional CB1 receptor binding in the hippocampus and (2) add further proof to the validity of the ABA model to mimic aspects of human disease.”

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