“A combination of the oils of sesame, hemp, wild pistachio, and walnut has been used for treatment of skin disorders, including wound burns, in some parts of Kerman, Iran. Evaluation of this remedy in the form of a pharmaceutical formulation in animal models can pave the way for its future application in wound burn healing in humans.
This experimental study investigated the healing potential of a new formula (NF) based on folk medicine from Iran for the treatment of third degree burns in mice. The formula was a combination of the oils of four plants: sesame (Sesamum indicum L.), wild pistachio (Pistacia atlantica Desf.), hemp (Cannabis sativa L.), and walnut (Juglans regia L.).
When compared to the controls, NF significantly improved wound contraction after day 10. Histopathological and immunohistochemical findings confirmed the efficacy of the NF.
A new therapeutic remedy was introduced for the treatment of burn wounds.
Further clinical and molecular studies are suggested to determine the exact mechanism(s) involved in the burn wound healing effect of NF.”