“delta 9-Tetrahydrocannabinol (THC), prochlorperazine, and placebo were compared.
Nausea was absent in 40 of 55 patients receiving THC, in 8 of 55 patients receiving prochlorperazine, and in 5 of 55 in the placebo group.
THC appeared to be more efficacious in controlling the emesis associated with cyclophosphamide, 5-fluorouracil, and doxorubicin and less so for nitrogen mustard and the nitrosourea.
THC appears to offer significant control of nausea in most patients and exceeds by far that provided by prochlorperazine.”