Regulation of Adult Neurogenesis by Cannabinoids

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“In the adult mammalian brain, new neurons are born throughout life, and these new cells may influence learning, memory, olfaction, and even mood. The putative function of these new neurons suggests that manipulation of adult neurogenesis could be used therapeutically in the future, and emphasizes the importance of understanding how neurogenesis is regulated. Voluntary exercise and antidepressants are examples of factors that increase neurogenesis, while stress and drugs of abuse – alcohol, nicotine, psychostimulants, opiates – decrease neurogenesis. In contrast to the clear negative influence of these drugs of abuse, cannabinoids have mixed influence, with some marijuana-like compounds actually enhancing neurogenesis.”  https://www.researchgate.net/publication/264424221_Regulation_of_Adult_Neurogenesis_by_Cannabinoids

“The role of cannabinoids in adult neurogenesis”  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4543605/

“Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects”  http://www.jci.org/articles/view/25509

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