Target-Selective Phototherapy Using a Ligand-Based Photosensitizer for Type 2 Cannabinoid Receptor.

“Phototherapy is a powerful, noninvasive approach for cancer treatment, with several agents currently in clinical use.

…we developed a phototherapy agent that combines a functional ligand and a near infrared phthalocyanine dye. Our target is type 2 cannabinoid receptor (CB2R), considered an attractive therapeutic target for phototherapy given it is overexpressed by many types of cancers that are located at a surface or can be reached by an endoscope.

Overall, this opens up the opportunity for development of an alternative treatment option for CB2R-positive cancers.”

http://www.ncbi.nlm.nih.gov/pubmed/24583052

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