Anti-inflammatory compound from cannabis found in herbs

“A compound found in cannabis as well as in herbs such as basil and oregano could help to treat inflammatory bowel diseases and arthritis, Swiss scientists believe.”

Model of the interaction of BCP with the CB2 receptor

“(E)-beta-caryophyllene (BCP) is an aromatic sesquiterpene that has used for many years as a food additive because of its peppery flavour. The researchers now say that it interacts selectively with one of two cannabinoid receptors, CB2, blocking the chemical signals that lead to inflammation without triggering cannabis’s mood-altering effects.
Many cannabinoids bind to the CB2 receptor, but few target it selectively. Most also interact with CB1, which is responsible for cannabis’ psychoactive properties. CB1 is found in brain tissue, whereas CB2is found only in cells elsewhere in the body.”


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