“Δ9-tetrahydrocannabinol (THC) promotes sleep in animals; clinical use of THC is associated with somnolence (sleepiness)…
These findings suggest that tolerance to the somnolent effects of THC may have occurred…
Somnolence from oral THC may dissipate with chronic, high-dose use.
This has implications for patients who may take chronic oral THC for medicinal purposes, including cannabis dependence treatment.”