Cannabinoid Type 1 and Type 2 Receptor Antagonists Prevent Attenuation of Serotonin-Induced Reflex Apneas by Dronabinol in Sprague-Dawley Rats.

“The prevalence of obstructive sleep apnea (OSA) in Americans is 9% and increasing…

Vagal afferent neurons are inhibited by cannabinoid type 1 (CB1) or cannabinoid type 2 (CB2) receptors in animal models of vagally-mediated behaviors…

These findings underscore the therapeutic potential of dronabinol (THC) in the treatment of OSA and implicate participation of both cannabinoid receptors in dronabinol’s apnea suppression effect.”

http://www.ncbi.nlm.nih.gov/pubmed/25350456

http://www.thctotalhealthcare.com/category/sleep-apnea/

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