Cannabidiol affects circadian clock core complex and its regulation in microglia cells.

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“Cannabis is often used by consumers for sleep disorders.

Our study suggests that circadian rhythm in microglial cells is deregulated by CBD but not by THC.

It is consistent with clinical observations of the use of therapeutic cannabis to treat insomnia.”

https://www.ncbi.nlm.nih.gov/pubmed/30307084

https://onlinelibrary.wiley.com/doi/abs/10.1111/adb.12660

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