“These data indicate that cannabinoids have robust diuretic effects in rats that are mediated via CB1 receptor mechanisms.
Overall, our data indicate that diuresis is a CB1-mediated effect that may serve as a reliable and objective physiologic measure of cannabinoid action in rats; the circumstances under which these results represent a potential therapeutic benefit or potential liability of cannabinoids remain to be determined.
The implications of these findings currently are poorly understood, although a better understanding of mechanisms and sites of action by which cannabinoids increase urine loss may lead to the rational development of novel cannabinergic medications.” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533417/
“Diureticsaremedicinesthathelpreducetheamount of water in thebody. Diuretics areused to treatthebuildup of excessfluid in thebodythatoccurswithsomemedicalconditionssuch ascongestiveheart failure, liverdisease,andkidney disease. Somediureticsarealsoprescribed to treathighbloodpressure.Thesedrugsact on thekidneys to increaseurineoutput.Thisreducestheamount of fluid in thebloodstream,which in turnlowersbloodpressure.” http://medical-dictionary.thefreedictionary.com/diuretics