Cannabis Linked To Crohn’s Cure

“Smoking cannabis may be key in treating Crohn’s disease, research suggest.

In a recent trial marijuana was shown to induce ‘complete remission’ for patients suffering from the condition, which is also known as inflammatory bowel disease.

Scientists at Meir Medical Center, Israel, studied 21 people with severe Crohn’s disease who did not respond to various therapies.

They split the patients into two groups: 11 were given a joint to smoke twice a day for eight weeks, while 10 were given a placebo cigarette which contained no trace of cannabinoids.

A ‘complete remission’ of Crohn’s disease was recorded in 5/11 (45%) of the cannabis group and 1/10 in the placebo group.

A total of 10/11 patients in the cannabis group responded to the clinical trial with Crohn’s symptoms (which include pain, diarrhoea, tiredness and weight loss) significantly reduced.

In addition, study authors wrote: “Subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.”

“Further studies, with larger patient groups and a non-smoking mode of intake, are warranted,” they added.”

http://www.huffingtonpost.co.uk/2013/05/21/cannabis-treatment-inflammatory-bowel-disease-crohns_n_3311278.html?utm_hp_ref=uk%3Fncid%3DGEP

Please Note: The title of this article has been changed to “Could Cannabis Cure Crohn’s Disease?”

Study Adds to Evidence That Cigarettes Are Gateway to Marijuana

“Teen smokers who rationalize their use of cigarettes by saying, “At least, I’m not doing drugs,” may not always be able to use that line.

New research to be presented Sunday, May 5, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC, supports the theory that cigarettes are a gateway drug to marijuana.

“Contrary to what we would expect, we also found that students who smoked both tobacco and marijuana were more likely to smoke more tobacco than those who smoked only tobacco,” said study author Megan Moreno, MD, MSEd, MPH, FAAP, an investigator at Seattle Children’s Research Institute and associate professor of pediatrics at the University of Washington.

Dr. Moreno and her colleagues randomly selected incoming college students from two universities — one in the Northwest and one in the Midwest — to participate in the longitudinal study. Students were interviewed prior to entering college and again at the end of their freshman year regarding their attitudes, intentions and experiences with substances.

Specifically, students were asked if they had used tobacco or marijuana ever in their lives and in the past 28 days. Researchers also assessed the quantity and frequency of marijuana and tobacco use in the past 28 days.

Results showed that prior to entering college, 33 percent of the 315 participants reported lifetime tobacco use, and 43 percent of lifetime users were current users. In addition, tobacco users were more likely to have used marijuana than those who did not use tobacco.

By the end of their freshman year, 66 percent of participants who reported tobacco use prior to entering college remained current users with an average of 34 tobacco episodes per month. Of these, 53 percent reported concurrent marijuana use. Overall, users of both substances averaged significantly more tobacco episodes per month than current users of tobacco only (42 vs. 24).

“These findings are significant because in the past year we have seen legislation passed that legalizes marijuana in two states,” Dr. Moreno said. “While the impact of these laws on marijuana use is a critical issue, our findings suggest that we should also consider whether increased marijuana use will impact tobacco use among older adolescents.”

Future work should involve designing educational campaigns highlighting the increased risks of using these substances together, Dr. Moreno concluded.”

http://www.sciencedaily.com/releases/2013/05/130505073742.htm

Marijuana as a Gateway Drug: The Myth That Will Not Die – TIME

307_Marijuana

 

“Of all the arguments that have been used to demonize marijuana, few have been more powerful than that of the “gateway effect”: the notion that while marijuana itself may not be especially dangerous, it ineluctably leads to harder drugs like heroin and cocaine…” 

“The problem here is that correlation isn’t cause. Hell’s Angels motorcycle gang members are probably more 104 times more likely to have ridden a bicycle as a kid than those who don’t become Hell’s Angels, but that doesn’t mean that riding a two-wheeler is a “gateway” to joining a motorcycle gang. It simply means that most people ride bikes and the kind of people who don’t are highly unlikely to ever ride a motorcycle…”

“Scientists long ago abandoned the idea that marijuana causes users to try other drugs: as far back as 1999, in a report commissioned by Congress to look at the possible dangers of medical marijuana, the Institute of Medicine of the National Academy of Sciences wrote:

Patterns in progression of drug use from adolescence to adulthood are strikingly regular. Because it is the most widely used illicit drug, marijuana is predictably the first illicit drug most people encounter. Not surprisingly, most users of other illicit drugs have used marijuana first. In fact, most drug users begin with alcohol and nicotine before marijuana — usually before they are of legal age.

In the sense that marijuana use typically precedes rather than follows initiation of other illicit drug use, it is indeed a “gateway” drug. But because underage smoking and alcohol use typically precede marijuana use, marijuana is not the most common, and is rarely the first, “gateway” to illicit drug use. There is no conclusive evidence that the drug effects of marijuana are causally linked to the subsequent abuse of other illicit drugs.”

“Since then, numerous other studies have failed to support the gateway idea…”

Read more: http://healthland.time.com/2010/10/29/marijuna-as-a-gateway-drug-the-myth-that-will-not-die/

Alcoholism Linked To Drinking During Puberty, Says New Study

“In the U.S., alcohol is the most commonly used drug among persons under 21 years of age, and a new study says that the earlier a person starts drinking, the more likely he is to become addicted.”
 
teens drinking

 

“Are teenagers who have their first drink during puberty more likely to become addicted to alcohol? A new study from Germany on youth drinking says yes.”

http://www.eurekalert.org/pub_releases/2013-05/ace-ywh051013.php

“Researchers at the University of Heidelberg found that the earlier someone starts consuming alcohol, the greater their risk of becoming an alcoholic. After monitoring the drinking habits of 283 young adults over a four-year period and noting their drinking behaviors at ages 19, 22 and 23, the research team found that those who started drinking earlier tended to drink more and more frequently later.”

Read more: http://www.isciencetimes.com/articles/5211/20130520/alcoholism-teen-drinking-puberty-new-study-binge.htm 

No ‘Smoking’ Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse

“Marijuana is not a “gateway” drug that predicts or eventually leads to substance abuse, suggests a 12-year University of Pittsburgh study. Moreover, the study’s findings call into question the long-held belief that has shaped prevention efforts and governmental policy for six decades and caused many a parent to panic upon discovering a bag of pot in their child’s bedroom.

The Pitt researchers tracked 214 boys beginning at ages 10-12, all of whom eventually used either legal or illegal drugs. When the boys reached age 22, they were categorized into three groups: those who used only alcohol or tobacco, those who started with alcohol and tobacco and then used marijuana (gateway sequence) and those who used marijuana prior to alcohol or tobacco (reverse sequence).

Nearly a quarter of the study population who used both legal and illegal drugs at some point — 28 boys — exhibited the reverse pattern of using marijuana prior to alcohol or tobacco, and those individuals were no more likely to develop a substance use disorder than those who followed the traditional succession of alcohol and tobacco before illegal drugs, according to the study, which appears in this month’s issue of the American Journal of Psychiatry.

“The gateway progression may be the most common pattern, but it’s certainly not the only order of drug use,” said Ralph E. Tarter, Ph.D., professor of pharmaceutical sciences at the University of Pittsburgh School of Pharmacy and lead author of the study. “In fact, the reverse pattern is just as accurate for predicting who might be at risk for developing a drug dependence disorder.”

In addition to determining whether the gateway hypothesis was a better predictor of substance abuse than competing theories, the investigators sought to identify characteristics that distinguished users in the gateway sequence from those who took the reverse path. Out of the 35 variables they examined, only three emerged to be differentiating factors: Reverse pattern users were more likely to have lived in poor physical neighborhood environments, had more exposure to drugs in their neighborhoods and had less parental involvement as young children. Most importantly, a general inclination for deviance from sanctioned behaviors, which can become evident early in childhood, was strongly associated with all illicit drug use, whether it came in the gateway sequence, or the reverse.

While the gateway theory posits that each type of drug is associated with certain specific risk factors that cause the use of subsequent drugs, such as cigarettes or alcohol leading to marijuana, this study’s findings indicate that environmental aspects have stronger influence on which type of substance is used. That is, if it’s easier for a teen to get his hands on marijuana than beer, then he’ll be more likely to smoke pot. This evidence supports what’s known as the common liability model, an emerging theory that states the likelihood that someone will transition to the use of illegal drugs is determined not by the preceding use of a particular drug but instead by the user’s individual tendencies and environmental circumstances.

“The emphasis on the drugs themselves, rather than other, more important factors that shape a person’s behavior, has been detrimental to drug policy and prevention programs,” Dr. Tarter said. “To become more effective in our efforts to fight drug abuse, we should devote more attention to interventions that address these issues, particularly to parenting skills that shape the child’s behavior as well as peer and neighborhood environments.”

Indeed, according to the study, interventions focusing on behavior modification may be more effective prevention tactics than current anti-drug initiatives. For example, providing guidance to parents — particularly those in high-risk neighborhoods — on how to boost their caregiving skills and foster bonding with their children, could have a measurable effect on a child’s likelihood to smoke marijuana. Also, early identification of children who exhibit antisocial tendencies could allow for interventions before drug use even begins.

Although this research has significant implications for drug abuse prevention approaches, Dr. Tarter notes that the study has some limitations. First, as only male behaviors were studied, further investigation should explore if the results apply to women as well. Also, the examination of behaviors in phases beyond alcohol and marijuana consumption in the gateway series will be necessary.

Other study authors include Michael Vanyukov, Ph.D., and Maureen Reynolds, Ph.D., and Levent Kirisci, Ph.D., also of the University of Pittsburgh School of Pharmacy; and Duncan Clark, M.D., Ph.D., of the University of Pittsburgh School of Medicine. The research was funded by the National Institute on Drug Abuse.”

http://www.sciencedaily.com/releases/2006/12/061204123422.htm

Can Marijuana really be used to treat obesity?

“Some of you may read that title and are subconsciously checking off another reason why pot is fucking awesome. Good for you, the perception of marijuana as  an illicit substance has been changing steadily over the course of the decades. Several opinion polls now indicate that a majority of Americans now support the legalization of marijuana, conclusively proving that people like to get high.

Aside from getting high and playing Xbox live, it now appears that marijuana use may actually reduce the likelihood of obesity in individuals who smoke pot regularly. According to a study recently published in the American Journal of Epidemiology, regular users of cannabis have a much lower prevalence of obesity than non users. Even when the researchers adjusted for other factors that can contribute to body fat such as tobacco use, age or gender, the correlation remained strong.”

Read more:http://scallywagandvagabond.com/2013/05/can-marijuana-really-be-used-to-treat-obesity/

Cannabis Compounds can Help Treat Obesity

“Two cannabis compounds could be a new weapon in the fight against obesity, say researchers. Animal tests have shown these compounds can help treat type two diabetes while also lowering levels of cholesterol in the blood stream and fat in key organs like the liver.”

 Cannabis Compounds can Help Treat Obesity

“Scientists also found the compounds also had an impact on the level of fat and its response to insulin, a hormone that controls blood sugar levels, the Telegraph reports.

THCV was also found to increase the animals’ sensitivity to insulin while also protecting the cells that produce insulin, allowing them to work better and for longer.

Steph Wright, director of research and development at GW Pharmaceuticals developing the drugs, said: “The results in animal models have been very encouraging. We are interested in how these drugs effect the fat distribution and utilisation in the body as a treatment for metabolic diseases…”

Mike Cawthorne, director of metabolic research at the University of Buckingham who has been conducting the animal studies, said: “Over all, it seems these molecules increase energy expenditure in the cells of the body by increasing the metabolism”.”
 
 

Now they’re telling us smoking weed will also help fend off diabetes – MSN

Man smoking a joint (©RL/KEYSTONE USA/Rex Features) 

“The magical weed that helps us stay trim, be less crazy, control seizures, cure Crohn’s, rescue the economy and make watching TV game shows more enjoyable is now being credited for possibly reducing the risk of diabetes, too. Analyzing statistics from the Centers for Disease Control and Prevention’s “National Health and Nutrition Examination Survey,” researchers uncovered the good news that current marijuana users had 16 percent lower fasting insulin levels and 17 percent lower levels of insulin resistance than their nonstoner friends.

Bonus: Scientists found that pot users also had slimmer waistlines and higher levels of “good” cholesterol.”

http://now.msn.com/marijuana-may-fight-diabetes-researchers-say 

Study: Why Pot Smokers Are Skinnier

“Marijuana users had smaller waists and scored higher across several measures of blood sugar regulation.”
 
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“”Marijuana use is associated with an acute increase in caloric intake,” goes the clinical jargon for popular lore. Still despite eating more while high (by some measures, over 600 extra calories per day), marijuana users’ extra intake doesn’t seem to be reflected in increased BMI. Indeed, studies have identified a reduced prevalence of obesity in the pot smoking community…
 

IMPLICATIONS: Although they’re not sure exactly how it happens, write the authors, these findings suggest that marijuana somehow works to improve insulin control, regulating body weight and perhaps explaining why marijuana users have a lower incidence of diabetes. Adding to the big questions — “can weed can treat obesity?” and “marijuana makes you skinny?!” — is the possibility that marijuana might be useful in helping people to manage their blood sugar.”

Read more: http://www.theatlantic.com/health/archive/2013/05/study-why-pot-smokers-are-skinnier/275846/

Regular Marijuana Users May Be Skinnier, Have Better Blood Sugar Control: Study

“People who regularly smoke marijuana may have better control of their blood sugar and may be skinnier than non-marijuana users, according to a new study.”

Marijuana Users Skinnier
 
“The research, published in the American Journal of Medicine, shows that people who reported regularly using marijuana had a lower risk of insulin resistance and had lower fasting insulin levels, compared with people who never used marijuana. Researchers also found an association between using marijuana and having a smaller waist circumference and higher levels of “good” HDL cholesterol, compared with non-users. The research was conducted by scientists from Beth Israel Deaconess Medical Center, the University of Nebraska and the Harvard School of Public Health.”