Stroke Risk Caused By Tobacco Not Cannabis

“Prohibitionists are grasping at straws by claiming that cannabis is linked to strokes, Norml president Julian Crawford says.

In the Auckland University study, all but one of the stroke patients who were cannabis users also used tobacco regularly.

According to the US National Stroke Association, “Smoking tobacco doubles the risk for stroke when compared to a non-smoker. It reduces the amount of oxygen in the blood, causing the heart to work harder and allowing blood clots to form more easily.”

“Prohibitionists are scraping the bottom of the barrel by claiming that cannabis doubles the risk of stroke, when this result has already been linked to tobacco use,” Mr Crawford said.

“There is nothing scientific about this study and it should be discredited by all rational individuals.””

http://www.scoop.co.nz/stories/GE1302/S00011/stroke-risk-caused-by-tobacco-not-cannabis.htm

A Marijuana Bud A Day Keeps The Stroke Away

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http://patients4medicalmarijuana.wordpress.com/2013/01/26/a-marijuana-bud-a-day-keeps-the-stroke-away/

“Heart Surgeon: “Marijuana everyday reduces stroke risk by 50%”. A bud a day keeps the stroke away! That is the claim being made by this Medical Doctor who is also an avid medical marijuana supporter.”  https://www.youtube.com/watch?v=-fM5T_vty58

Cannabis ‘May Help Stroke Recovery By Improving Brain Functions After The Attack’

smoke cannabis

Cannabis may help to reduce brain damage after a stroke, new research suggests.

Chemical compounds found in the plant could help shrink the area of the brain affected by stroke, the study suggests.

Cannabinoids that are found in the plant as well as those that can be made artificially and those that are found naturally in the body can also help improve brain function after a stroke attack, the authors said.”

http://www.huffingtonpost.co.uk/2013/12/03/cannabis-may-help-stroke-recovery_n_4376100.html

Stroke survivors could be given cannabis to reduce brain damage

“SCIENTISTS are considering running a trial which would see stroke survivors given the illegal class-B drug cannabis in a bid to reduce brain damage.

The “exciting” research has been compiled by researchers at the University of Nottingham, who have pulled together research from around the world to suggest that ‘cannabinoids’ – chemicals related to those found in cannabis, some of which also occur naturally in the body – could reduce the size of stroke and improve neurological function.

The research – so far which has only been done on rats – indicates that all three classes of cannabinoid could be effective in shrinking the area of the brain affected by stroke and in recovering neurological function.

Dr Tim England honorary consultant stroke physician at the University of Nottingham and Royal Derby Hospital led the study.

He said: “This meta-analysis of pre-clinical stroke studies provides valuable information on the existing, and importantly, missing data on the use of cannabinoids as a potential treatment for stroke patients.”

http://www.nottinghampost.com/Stroke-survivors-given-cannabis-reduce-brain/story-20249666-detail/story.html

 

Cannabis ‘may help stroke recovery’

“Cannabis may help to reduce brain damage after a stroke, new research suggests.

Chemical compounds found in the plant could help shrink the area of the brain affected by stroke, the study suggests.

Cannabinoids that are found in the plant as well as those that can be made artificially and those that are found naturally in the body can also help improve brain function after a stroke attack, the authors said.”

http://www.belfasttelegraph.co.uk/breakingnews/offbeat/cannabis-may-help-stroke-recovery-29803527.html

Cannabis could help fix brain after stroke – research

Researchers have identified the potential for cannabinoids to reduce brain damage caused by stroke.
Photo / Thinkstock

“Cannabis may help to reduce brain damage after a stroke, new research suggests.

Chemical compounds found in the plant could help shrink the area of the brain affected by stroke, the study says.

Cannabinoids in the plant, as well as those that can be made artificially and those found naturally in the body, can also help improve brain function after a stroke attack, the authors said.”

http://www.nzherald.co.nz/lifestyle/news/article.cfm?c_id=6&objectid=11166326

Marijuana & Stroke: Pot Compounds Protect Brain, New Meta-Study Shows

“Cannabinoids, chemicals related to those found in cannabis could be effective in restoring neurological function by shrinking the area of the brain affected by stroke, according to a new study led by Dr. Tim England, Honorary Consultant Stroke Physician at the University of Nottingham and Royal Derby Hospital.

Stroke, a leading cause of adult disability in the UK leaves over half of all survivors dependent on others for life. Over one million people are living with the effects of stroke and it is reported that in the UK alone, over 150,000 people have a stroke every year. Finding new treatments to help survivors recover quickly has never been more important.

The authors examined 94 studies evaluating the effects of cannabinoids on 1022 mice, monkeys, and male rats. Cannabinoids can be classified into endocannabinoids that occur naturally in the body, phytocannabinoids that are obtained from plant extracts, and synthetic cannabinoids.

A meta-analysis of experimental studies conducted by the researchers at the University of Nottingham identifies the potential of all three categories of these compounds potential to reduce brain damage caused by stroke and help improve brain function after an attack.

The U.S. government sought a patent in 2001 for the naturally occuring marijuana molecule, cannabidiol, for use as a brain protector during stroke. ”

http://blog.sfgate.com/smellthetruth/2013/12/11/marijuana-stroke-pot-compounds-protect-brain-new-meta-study-shows/

Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment

Figure 1.

“THE CONSEQUENCES OF ISCHEMIC INJURY in liver, heart, and brain can be ameliorated by cannabinoids, a group of diverse compounds that include constituents of the plant Cannabis sativa (phytocannabinoids), endogenous lipids (endocannabinoids), and synthetic substances. Most of the effects of cannabinoids are mediated by the G-protein-coupled receptors cannabinoid receptor 1 (CB1) and cannabinoid receptor 2 (CB2)… 

Cannabinoids protect against ischemic stroke…

Activation of the cannabinoid 2 receptor (CB2) reduces ischemic injury in several organs…

In conclusion, our data demonstrate that by activating p38 in neutrophils, CB2 agonists inhibit neutrophil recruitment to the brain and protect against ischemic brain injury.”

http://www.fasebj.org/content/24/3/788.long

Cannabis gives stroke patients hope

“New research by University of Otago scientists suggests some mechanisms in the brain targeted by cannabis could become drugs targets to counter brain cell damage after a stroke.

Researchers from the Medical School’s Department of Pharmacology and Toxicology have been the first in the world to show the cannabinoid CB2 receptor appears in the rat brain following a stroke. Their findings were published recently in the journal Neuroscience Letters.

Dr John Ashton says the CB2 receptor is a protein produced as part of the body’s immune response system.

“This response is triggered by stroke and causes the inflammation that leads to damage in the area of the brain around where the stroke has occurred.

“If the inflammation can be stopped or reduced then it offers the hope of reducing the extent of the damage caused by stroke – and CB2 offers a potential target for such a drug.””

http://www.sciencealert.com.au/news/20071404-15007.html

“Cerebral hypoxia-ischemia and middle cerebral artery occlusion induce expression of the cannabinoid CB2 receptor in the brain. The presence of CB2-positive cells in the brain following stroke may provide a novel strategy for cannabinoid-mediated intervention into stroke induced neurodegeneration without the psychoactive effects of CB1 receptor stimulation.” https://www.ncbi.nlm.nih.gov/pubmed/17123706

Cannabis may help stroke recovery

“CANNABIS may help to reduce brain damage after a stroke, new research suggests.

Chemical compounds found in the plant could help shrink the area of the brain affected by stroke, the study says.

Cannabinoids in the plant, as well as those that can be made artificially and those found naturally in the body, can also help improve brain function after a stroke attack, the authors said.

The study, which is to be presented to the annual UK Stroke Forum, examined previous studies conducted on the effect of the compound.

The authors, from the University of Nottingham, examined 94 studies evaluating the effects of cannabinoids on 1022 male rats, mice or monkeys.

They say the chemical “shows promise as a neuroprotective treatment for stroke”.

“This meta-analysis of pre-clinical stroke studies provides valuable information on the existing, and importantly, missing data on the use of cannabinoids as a potential treatment for stroke patients,” said lead author Dr Tim England, honorary consultant stroke physician at the University of Nottingham and Royal Derby Hospital.

Dr Dale Webb, director of research and information at the Stroke Association, added: “Stroke is the leading cause of adult disability in the UK, with more than half of all stroke survivors left dependent on others for everyday activities. With more people in the UK surviving a stroke, it’s never been more important to find new treatments to help more stroke patients make better recoveries.

“This new research is an example of the many new developments in the field of stroke which are being presented at this year’s UK Stroke Forum.

“The findings have identified the potential for cannabinoids to reduce brain damage caused by stroke.”

http://www.news.com.au/world/breaking-news/cannabis-may-help-stroke-recovery/story-e6frfkui-1226774100340