“Our results indicate that cannabidiol exerts a combination of neuroprotective, anti-oxidative and anti-apoptotic effects against beta-amyloid peptide toxicity, and that inhibition of caspase 3 appearance from its inactive precursor, pro-caspase 3, by cannabidiol is involved in the signalling pathway for this neuroprotection.”
Tag Archives: endocannabinoid system
Cannabis Science Presents Newest Photographs From 3rd Cancer Patient That Show Cancer Tumors Dying and Areas That Are Now Pain Free
January 30, 2012
“DENVER–(BUSINESS WIRE)– Cannabis Science, Inc. (OTCBB:CBIS.OB) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is pleased to share new photographs from this cancer patient with severe squamous cell carcinoma. These pictures clearly show that this patient, with previously treatment-resistant tumors, continues to make obvious improvement. The tumors appear to be dying and then healing after treatment with cannabis-based extracts.”
Cannabis Science Updates Second Medical Cannabis Cancer Patient Suffering from Squamous Cell Carcinoma Photo-documents Cannabis Extracts Killing Cancerous Tumor
“Cannabis Science, Inc. (OTCBB: CBIS) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is very pleased to announce that the second patient suffering from basal cell carcinoma (skin cancer) has self-administered cannabis extracts that appear to have eradicated the cancer.”
“Currently it appears that the aforementioned patient will be able to avoid any surgical procedures such as, standard surgical excision (Mohs Surgery), and other various types of treatment for skin cancer, like chemotherapy, radiation, and cryosurgery, by using the cannabis extracts…”
Cannabis Science Reports Apparent Success For 3rd Self-Medicated Cancer Patient
“Cannabis Science, Inc., a pioneering US biotech company developing pharmaceutical cannabis products, is happy to report an additional, apparently successful, self-medicated cannabis treatment for a cancer patient.
This case is very graphic in nature. One of the patient’s physicians said it was the worst case of squamous cell carcinoma cancer he had ever seen, while another refused to continue tending to the patient.
While this patient’s self-administered treatment with cannabis extracts is still in progress, the results after just two weeks of treatment are dramatic. Some of the tumors have disappeared and others have significantly shrunk to a fraction of their original size. Simultaneously, the patient has had a significant decrease in pain, improved sleeping (the 1st full night of sleep in 3 years), as well as relief from the symptoms of multiple sclerosis that the patient also suffers from. This self-treatment is a work in progress.”
Cannabis Science Publishes List of Over 800 Peer-Reviewed Cannabis and Cancer References From Scientists Around the World
“This list of peer-reviewed manuscripts, provides support for the anecdotal observations of an increasing number of patients claiming successful cancer treatment using medical cannabis extracts.”
“The scientific documentation of the anti-cancer and anti-metastatic properties of cannabinoids is a driving force behind behind our long-term goal, to make high quality, effective, reliable and safe cannabis extracts available to the public beyond the borders of current medical marijuana states.”
Cannabis Science Provides Physician’s Documentation That Confirms Successful Treatment of Skin Cancer
April 6, 2011 “We are pleased to announce that we have physician’s documentation that confirms the successful treatment of basal cell carcinoma that resulted from the application of a topical cannabis extract.”
Cannabis and amyotrophic lateral sclerosis: hypothetical and practical applications, and a call for clinical trials
“Cannabis and amyotrophic lateral sclerosis… Significant advances have increased our understanding of the molecular mechanisms of amyotrophic lateral sclerosis (ALS)… It appears that a number of abnormal physiological processes occur simultaneously in this devastating disease. Ideally, a multidrug regimen… would be required to comprehensively address the known pathophysiology of ALS.REMARKABLY, CANNABIS APPEARS to have activity in all of those areas. Preclinical data indicate that cannabis has POWERFUL antioxidative, anti-inflammatory, and neuroprotective effects… Based on the currently available scientific data, it is reasonable to think that cannabis might significantly slow the progression of ALS, potentially extending LIFE expectancy and substantially reducing the overall burden of the disease.”
The Cannabinergic System as a Target for Anti-inflammatory Therapies
“Cell-based experiments or in vivo animal testing suggest that regulation of the endocannabinoid circuitry can impact almost every major function associated with the immune system. These studies were assisted by the development of numerous novel molecules that exert their biological effects through the endocannabinoid system. Several of these compounds were tested for their effects on immune function, and the results suggest therapeutic opportunities for a variety of inflammatory diseases such as multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, allergic asthma, and autoimmune diabetes through modulation of the endocannabinoid system.”
http://www.ingentaconnect.com/content/ben/ctmc/2006/00000006/00000013/art00008
THC inhibits primary marker of Alzheimer’s disease
“With its strong inhibitory abilities, the study said, THC “may provide an improved therapeutic for Alzheimer’s disease” that would treat “both the symptoms and progression” of the disease.”
Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
TRUTH: “Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors… nonpsychoactive cannabinoids can potentiate glycine receptors (GlyRs), an important target for nociceptive regulation at the spinal level… We report that systemic and intrathecal administration of cannabidiol (CBD), a major nonpsychoactive component of marijuana, and its modified derivatives significantly suppress chronic inflammatory and neuropathic pain without causing apparent analgesic tolerance… These cannabinoids may represent a novel class of therapeutic agents for the treatment of chronic pain and other diseases involving GlyR dysfunction.”