“Recent research found that a liquid form of therapeutic marijuana can provide cure to children with treatment-resistant epilepsy.
The said study will be presented at the American Academy of Neurology’s 67th Annual Meeting in Washington, DC in late April.”
http://au.ibtimes.com/medicinal-marijuana-may-help-cure-children-severe-epilepsy-1440398
“Pinene (or α-pinene) is an aromatic compound commonly found in cannabis that smells a lot like – you guessed it – a forest of pine trees.” http://www.leafly.com/news/cannabis-101/what-is-pinene-and-what-are-the-benefits-of-this-cannabis-terpene
“Anti-inflammatory and chondroprotective activity of (+)-α-pinene: structural and enantiomeric selectivity. Previous studies have suggested that α-pinene, a common volatile plant metabolite, may have anti-inflammatory effects in human chondrocytes, thus exhibiting potential antiosteoarthritic activity… The data obtained show isomer- and enantiomer-selective anti-inflammatory and anticatabolic effects of α-pinene in human chondrocytes, (+)-α-pinene being the most promising for further studies to determine its potential value as an antiosteoarthritic drug.” http://www.ncbi.nlm.nih.gov/pubmed/24455984
“The therapeutic efficacy of α-pinene in an experimental mouse model of allergic rhinitis. In the present study, the therapeutic effect and underlying mechanism of α-pinene (α-PN) in the ovalbumin (OVA)-sensitized allergic rhinitis (AR) model were investigated… Taken together, we suggest that α-PN is a promising anti-allergic agent and may be useful in the clinical management of AR.” http://www.ncbi.nlm.nih.gov/pubmed/25242385
“Structural and Thermodynamic Basis of (+)-α-Pinene Binding to Human Cytochrome P450 2B6… (+)-α-Pinene is a monoterpene hydrocarbon that is widely distributed in the environment and a potent P450 2B inhibitor. “ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3754432/
“Inhibitory effects of α-pinene on hepatoma carcinoma cell proliferation… Taken together, these findings indicate that α-pinene may be useful as a potential anti-tumor drug.” http://www.ncbi.nlm.nih.gov/pubmed/24815485
“Synergistic Antitumor Effect of α-pinene and β-pinene with Paclitaxel against Non-small-cell Lung Carcinoma (NSCLC).” http://www.ncbi.nlm.nih.gov/pubmed/25188609
“Biological activities of α-pinene and β-pinene enantiomers. The antimicrobial activities of the isomers and enantiomers of pinene were evaluated against bacterial and fungal cells.” http://www.ncbi.nlm.nih.gov/pubmed/23442885
“Microbial Synthesis of Pinene” http://pubs.acs.org/doi/abs/10.1021/sb4001382
“Effect of alpha-pinene on nuclear translocation of NF-kappa B in THP-1 cells.” http://www.ncbi.nlm.nih.gov/pubmed/15066217
“Protective effects of alpha-pinene in mice with cerulein-induced acute pancreatitis. Acute pancreatitis (AP) is a complicated inflammatory disease that has an unknown underlying pathogenesis. Because alpha-pinene can modulate inflammation, we examined whether alpha-pinene plays a role in AP… These findings suggest that alpha-pinene has an anti-inflammatory effect during cerulein-induced AP.” http://www.ncbi.nlm.nih.gov/pubmed/22982349
“You’ve heard about using marijuana and drugs derived from it to keep some of the side effects of toxic cancer chemotherapy in check. But what if smoking marijuana for 10 to 20 years could actually protect against certain tumors?
In a study, researchers have found that long-term pot smokers were roughly 62 percent less likely to develop head and neck cancers than people who did not smoke pot.”
“Researchers at Hebrew University have found that extracts from the cannabis plant can help strengthen human bones, preventing osteoporosis, according to an Israel21c report.”
http://www.israelnationalnews.com/News/News.aspx/96146#.VPH1lE33-ix
“Peripheral cannabinoid receptor, CB2, regulates bone mass… These results demonstrate that the endocannabinoid system is essential for the maintenance of normal bone mass by osteoblastic and osteoclastic CB2 signaling. Hence, CB2 offers a molecular target for the diagnosis and treatment of osteoporosis, the most prevalent degenerative disease in developed countries.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1334629/
“A LAKE Macquarie woman whose ‘‘aggressive’’ breast cancer spread to various parts of her body including her spine and lungs credits her remarkable recovery to cannabis oil.
Awaba woman Susannah Patch, 44, is one of a growing number of Hunter people who have treated themselves using an underground network of cannabis oil suppliers.
Although she had surgery, radiotherapy and chemotherapy, Ms Patch says most of her improvement has come since stopping chemotherapy against the advice of the cancer specialists and continuing with cannabis oil…
‘It is a distinct possibility that the cannabinoids may have ‘‘a place in the future treatment of cancer,’’
http://www.theherald.com.au/story/2587931/cannabis-oil-stopped-my-cancer/?cs=12
“It’s breast cancer awareness month. Please, BE AWARE:” http://www.thctotalhealthcare.com/its-breast-cancer-awareness-month-please-be-aware/
“A laboratory study of cannabidiol in estrogen receptor positive and estrogen receptor negative breast cancer cells showed that it caused cancer cell death while having little effect on normal breast cells.” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page2
“Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells… In summary, we showed that CBD, a plant-derived cannabinoid, preferentially kills breast cancer cells…” http://mct.aacrjournals.org/content/10/7/1161.full
“Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa,” http://www.ncbi.nlm.nih.gov/pubmed/19690824
“Cannabidiol (CBD) Shown To Kill Breast Cancer Cells” http://www.cafemom.com/group/99198/forums/read/19190923/Cannabidiol_CBD_Shown_To_Kill_Breast_Cancer_Cells
“Here, we show that Δ9-tetrahydrocannabinol (THC), reduces human breast cancer cell proliferation by blocking the progression of the cell cycle and by inducing apoptosis.” http://www.ncbi.nlm.nih.gov/pubmed/16818634
“Programmed Cell Death (Apoptosis)” http://www.ncbi.nlm.nih.gov/books/NBK26873/
“Cannabis has been shown to kill cancer cells…”
http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page1
“…cannabinoids may be able to kill cancer cells while protecting normal cells… A laboratory study of delta-9-THC… showed that it damaged or killed the cancer cells… A laboratory study of cannabidiol… showed that it caused cancer cell death…” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page2
“Cannabinoids appear to kill tumor cells but do not effect their nontransformed counterparts and may even protect them from cell death.” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4
“Cannabis oil stopped my cancer says Lake Macquarie’s Susannah Patch” http://www.theherald.com.au/story/2587931/cannabis-oil-stopped-my-cancer/?cs=12
“Smoking marijuana doesn’t have to be a bad thing – Especially if you have HD.
The idea that THC can be used to relieve disease symptoms isn’t a new thing – Glaucoma, HIV, and cancer patients have all benefited from the use of CB1 agonists whether in the form of marijuana leaves or a pharmacologically similar product (like dronabinol).
Nevertheless, the idea of using THC or other CB1 agonists for the treatment of HD is pretty new…
The results of this study suggest that THC and other CB1 compounds may not only be able to improve symptoms in already symptomatic HD patients, but also slow down the progression of such a devestating disease.
Good news all around and a great use of THC as far as I’m concerned (medical use and removal from schedule-1 anyone?!).”
“Guillermo Velasco and colleagues, at Complutense University, Spain, have provided evidence that suggests that cannabinoids such as the main active component of marijuana (THC) have anticancer effects on human brain cancer cells.
In the study, THC was found to induce the death of various human brain cancer cell lines and primary cultured human brain cancer cells by a process known as autophagy. Consistent with the in vitro data, administration of THC to mice with human tumors decreased tumor growth and induced the tumor cells to undergo autophagy.
As analysis of tumors from two patients with recurrent glioblastoma multiforme (a highly aggressive brain tumor) receiving intracranial THC administration showed signs of autophagy, the authors suggest that cannabinoid administration may provide a new approach to targeting human cancers.”
http://www.medicalnewstoday.com/releases/144770.php
“Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673842/
“Advocates for medical marijuana can take heart over the findings of two Canadian research teams.
A synthetic cannabinoid — similar to the compounds found in marijuana, but substantially stronger — causes the growth of new neurons and reduces anxiety and depression, investigators at the University of Saskatchewan here reported.
And researchers at the University of Calgary said they’ve found evidence that the brain contains so-called CB2 cannabinoid receptors, previously seen in immune tissue but thought not to exist in brain tissue. The discovery, they added, could lead to new drugs to treat nausea associated with cancer or AIDS.
Most so-called drugs of abuse — such as alcohol or cocaine — inhibit the growth of new neurons, according to Xia Zhang, M.D., Ph.D., of the University of Saskatchewan.
“Only marijuana promotes neurogenesis,” Dr. Zhang said.”
http://www.medpagetoday.com/Psychiatry/AnxietyStress/1934
“A synthetic substance similar to ones found in marijuana stimulates cell growth in regions of the brain associated with anxiety and depression, pointing the way for new treatments for these diseases, according to University of Saskatchewan medical research published today in The Journal of Clinical Investigation.
Xia Zhang, an associate professor in the U of S neuropsychiatry research unit, led the team that tested the effects of HU-210, a potent synthetic cannabinoid similar to a group of compounds found in marijuana. The synthetic version is about 100 times as powerful as THC, the compound responsible for the high experienced by recreational users.
The team found that rats treated with HU-210 on a regular basis showed neurogenesis – the growth of new brain cells in the hippocampus. This region of the brain is associated with learning and memory, as well as anxiety and depression.
The effect is the opposite of most legal and illicit drugs such as alcohol, nicotine, heroin, and cocaine.
“Most ‘drugs of abuse’ suppress neurogenesis,” Zhang says. “Only marijuana promotes neurogenesis.””
http://www.sciencedaily.com/releases/2005/10/051016083817.htm
“Veteran Matt Kahl has claimed that marijuana is the only drug that allows him to get over his PTSD, the side effect after two tours in the Afghanistan war.
Kbzk reported that in an interview with CBS News’ Barry Peterson (video below), Matt Kahl shared his experience with marijuana as a cure for his PTSD (post-traumatic stress disorder).
War veteran Matt Kahl came home to America after two tours in Afghanistan, a wounded soldier, physically and mentally. Kahl’s physical injuries wracked him with pain, and the mental anguish was overwhelming he had to take 15 different medications. The medication seemed short of helpful that Khal attempted suicide ten months after his return to America.
“About ten months after I got back, I attempted suicide. I was completely hopeless,” he said.
But then he discovered the “healing” effects of marijuana which had probably saved his life.
“Suddenly, my extremely overactive, hyper-vigilant mind started to calm down, and my pain gradually started to go away, too. I needed less of these other medications,” he revealed.
Shortly afterwards, Kahl was determined to move to another state where marijuana is legal so that he could “get his life back.” So he moved his family to Colorado.
Inquisitr reported that ever since the marijuana legalisation bill went into effect in Colorado, Denver’s crime rates have dropped by 10.6 percent compared to January of this year.
Matt Kahl now works with a support group called Grow4Vets in Colorado. He and other volunteers reportedly recently spent a day putting together bags of marijuana products to give away on holidays, like Memorial Day.
Current treatments of PTSD range from therapy to prescription drugs, but according to Grow4Vets founder Roger Martin, the group wants to replace the pills with marijuana.
“Anybody that’s been on narcotic medication especially wants to get off of it,” he said, adding that he really hasn’t met anybody who “just enjoys being in a drug stupor.”
Kbzk cited another veteran, marijuana shop owner Toni Fox’s father, who came home from Vietman suffering PTSD. Fox recalled her father struggled with PTSD his whole life that he eventually committed suicide when she was 14.
“I believe in my heart of hearts that, if he would have had access to cannabis, he would be alive today,” she said.
Despite Matt Kahl’s testimony, critics are still doubtful on the “healing” effects of marijuana, considering the fact that there is little or no scientific proof that it actually helps with PTSD.”
http://au.ibtimes.com/articles/557139/20140627/marijuana-cure-ptsd-matt-kahl.htm#.U64Y-5RX-uY
http://www.thctotalhealthcare.com/category/post-traumatic-stress-disorder-ptsd/