Marijuana May Smoke Out Crohn’s Disease Symptoms

“Crohn’s Disease treatment in the form of medical marijuana may result in a complete remission of symptoms in some people. A new study researched the effects of marijuana on this chronic condition that affects the digestive tract.”

Medical marijuana products are displayed at a medical dispensary
 
“Symptoms of the bowel condition include persistent diarrhea, rectal bleeding, abdominal cramps and pain. Crohn’s Disease can also cause severe vomiting, weight loss and arthritis. The feeling of low energy and fatigue is also common among people who suffer from Crohn’s Disease.
 
 Medical marijuana used as treatment has a significant effect on the symptoms of Crohn’s Disease, according to a new study.
 

In the very first placebo-controlled trial, researchers found that medical marijuana can reduce the symptoms of Crohn’s disease or eliminate them all together. Results of the study were published in the journal Clinical Gastroenterology and Hepatology.”

Read more: http://www.itechpost.com/articles/9298/20130516/marijuana-smoke-out-crohns-disease-symptoms.htm

Marijuana may help patients with Crohn’s disease, study says

“New research published earlier this month might have more patients with Crohn’s disease turning to medical marijuana for relief.”
 
Crohn’s disease is an inflammatory bowel disease that affects around 500,000 people in North America.

 

In a first-of-its-kind clinical trial, an 8-week treatment regimen involving daily smoking of marijuana ‘cigarettes’ resulted in a reduction in overall disease severity in 10 of the 11 patients that were studied. 5 of these patients experienced complete remission of their disease.

 

The results were published online in the journal Clinical Gastroenterology and Hepatology and authored by scientists at the Meir Medical Clinical in Israel. Israel has one of the most fastest growing medical marijuana programs in the world, with over 11,000 registered patients as of today — up from just 400 in 2009.

 

While the researchers say that their study was the first placebo-controlled trial — the “gold standard” when it comes to medical research — to investigate the effects of marijuana use on patients with Crohn’s disease, other studies have produced similar results.

 

Based on findings from both animal and human research, experts suggest that cannabis could play a role in the treatment of Crohn’s and other inflammatory bowel diseases by regulating intestinal hyperactivity, inflammation and pain.

 

Marijuana’s medical properties come directly from compounds known as cannabinoids, including the well-known tetrahydrocannabinol (THC) molecule. Interestingly, the cannabinoids found in the cannabis plant have been shown to mimic the activity of endocannabinoids – cannabinoids that are produced naturally by the human body.

 

Similarly, studies have identified a variety of digestive functions that can be modulated by cannabinoid activity, especially in inflammatory disease states.

 

Although the findings of the current study provide considerable support for the use of marijuana as a Crohn’s disease treatment, the authors call for more studies to “look into the role of cannabinoids in controlling inflammation and symptoms in inflammatory bowel disease.”

 

Indeed, larger studies may be able to provide stronger confirmation or perhaps refute the findings of the newest study, which failed to demonstrate complete remission of Crohn’s in the majority of the treatment group.

 

Still, the authors concluded their research by stating, “a short course of THC-rich cannabis produced significant clinical, steroid-free benefits to 11 patients with active Crohn’s disease, compared to placebo, without side effects.””

http://www.digitaljournal.com/article/350495

Smoking Marijuana Causes ‘Complete Remission’ of Crohn’s Disease, No Side Effects, New Study Shows

“Marijuana – scientific name “cannabis” – performed like a champ in the first-ever placebo-controlled trial of the drug to treat Crohn’s Disease, also known as inflammatory bowel disease.”

 

“The disease of the digestive tract afflicts 400,000 – 600,000 people in North America alone causing abdominal pain, diarrhea (which can be bloody), severe vomiting, weight loss, as well as secondary skin rashes, arthritis, inflammation of the eye, tiredness, and lack of concentration.

Smoking pot caused a “complete remission” of Crohn’s disease compared to placebo in half the patients who lit up for eight weeks, according to clinical trial data to be published the journal Clinical Gastroenterology and Hepatology.

Researchers at Israel’s Meir Medical Center took 21 people with intractable, severe Crohn’s disease and gave 11 of them two joints a day for eight weeks. “The standardized cannabis cigarettes” contained 23 percent THC and 0.5 percent CBD (cannabidiol). (Such marijuana is available on dispensary shelves in San Francisco, Oakland, and other cities that have regulated access to the drug.) The other ten subjects smoked placebo cigarettes containing no active cannabinoids.

Investigators reported that smoking weed caused a “complete remission” of Crohn’s Disease in five of the 11 subjects. Another five of the eleven test subjects saw their Crohn’s Disease symptoms cut in half. Furthermore, “subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.”

The study is the first placebo-controlled clinical trial to assess the consumption of cannabis for the treatment of Crohn’s, notes NORML. All of the patients had intractable forms of the disease and did not respond to conventional treatments. Still, the United States government claims that marijuana is as dangerous as heroin and has no medical use. U.S. Attorney Melinda Haag is waging a war on safe access to medical cannabis in the Bay Area.”

http://blog.sfgate.com/smellthetruth/2013/05/14/smoking-marijuana-cured-crohns-disease-with-no-side-effects-new-study-shows/

Marijuana Put My Crohn’s Disease Into Remission and It’s Not A Joke

Marijuana Put My Crohn’s Disease Into Remission and It’s Not A Joke

Choosing pot over pills may be the way to go for Crohn’s sufferers – MSN

A man smokes medical marijuana (© Rick Bowmer/AP)

“A new study published in the Clinical Gastroenterology and Hepatology journal shows that marijuana reduces the symptoms of Crohn’s disease, a condition affecting the bowel. Researchers at the Meir Medical Center in Israel rounded up 21 sufferers, 11 were instructed to smoke marijuana twice a day, while the other 10 were given placebo pot. Although that’s a fairly small test group, the results were pretty miraculous: Eight weeks later the stoners showed significant improvement and five had gone into remission. Unlike ingesting an endless stream of pills, researchers also revealed that partaking in a little ganja had “no significant side effects,” other than helping the group to sleep better and increasing their appetites.”

http://now.msn.com/marijuana-reduces-crohns-disease-symptoms-in-meir-medical-center-study#scpshrjp2

Study Adds to Evidence That Cigarettes Are Gateway to Marijuana

“Teen smokers who rationalize their use of cigarettes by saying, “At least, I’m not doing drugs,” may not always be able to use that line.

New research to be presented Sunday, May 5, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC, supports the theory that cigarettes are a gateway drug to marijuana.

“Contrary to what we would expect, we also found that students who smoked both tobacco and marijuana were more likely to smoke more tobacco than those who smoked only tobacco,” said study author Megan Moreno, MD, MSEd, MPH, FAAP, an investigator at Seattle Children’s Research Institute and associate professor of pediatrics at the University of Washington.

Dr. Moreno and her colleagues randomly selected incoming college students from two universities — one in the Northwest and one in the Midwest — to participate in the longitudinal study. Students were interviewed prior to entering college and again at the end of their freshman year regarding their attitudes, intentions and experiences with substances.

Specifically, students were asked if they had used tobacco or marijuana ever in their lives and in the past 28 days. Researchers also assessed the quantity and frequency of marijuana and tobacco use in the past 28 days.

Results showed that prior to entering college, 33 percent of the 315 participants reported lifetime tobacco use, and 43 percent of lifetime users were current users. In addition, tobacco users were more likely to have used marijuana than those who did not use tobacco.

By the end of their freshman year, 66 percent of participants who reported tobacco use prior to entering college remained current users with an average of 34 tobacco episodes per month. Of these, 53 percent reported concurrent marijuana use. Overall, users of both substances averaged significantly more tobacco episodes per month than current users of tobacco only (42 vs. 24).

“These findings are significant because in the past year we have seen legislation passed that legalizes marijuana in two states,” Dr. Moreno said. “While the impact of these laws on marijuana use is a critical issue, our findings suggest that we should also consider whether increased marijuana use will impact tobacco use among older adolescents.”

Future work should involve designing educational campaigns highlighting the increased risks of using these substances together, Dr. Moreno concluded.”

http://www.sciencedaily.com/releases/2013/05/130505073742.htm

Marijuana as a Gateway Drug: The Myth That Will Not Die – TIME

307_Marijuana

 

“Of all the arguments that have been used to demonize marijuana, few have been more powerful than that of the “gateway effect”: the notion that while marijuana itself may not be especially dangerous, it ineluctably leads to harder drugs like heroin and cocaine…” 

“The problem here is that correlation isn’t cause. Hell’s Angels motorcycle gang members are probably more 104 times more likely to have ridden a bicycle as a kid than those who don’t become Hell’s Angels, but that doesn’t mean that riding a two-wheeler is a “gateway” to joining a motorcycle gang. It simply means that most people ride bikes and the kind of people who don’t are highly unlikely to ever ride a motorcycle…”

“Scientists long ago abandoned the idea that marijuana causes users to try other drugs: as far back as 1999, in a report commissioned by Congress to look at the possible dangers of medical marijuana, the Institute of Medicine of the National Academy of Sciences wrote:

Patterns in progression of drug use from adolescence to adulthood are strikingly regular. Because it is the most widely used illicit drug, marijuana is predictably the first illicit drug most people encounter. Not surprisingly, most users of other illicit drugs have used marijuana first. In fact, most drug users begin with alcohol and nicotine before marijuana — usually before they are of legal age.

In the sense that marijuana use typically precedes rather than follows initiation of other illicit drug use, it is indeed a “gateway” drug. But because underage smoking and alcohol use typically precede marijuana use, marijuana is not the most common, and is rarely the first, “gateway” to illicit drug use. There is no conclusive evidence that the drug effects of marijuana are causally linked to the subsequent abuse of other illicit drugs.”

“Since then, numerous other studies have failed to support the gateway idea…”

Read more: http://healthland.time.com/2010/10/29/marijuna-as-a-gateway-drug-the-myth-that-will-not-die/

No ‘Smoking’ Gun: Research Indicates Teen Marijuana Use Does Not Predict Drug, Alcohol Abuse

“Marijuana is not a “gateway” drug that predicts or eventually leads to substance abuse, suggests a 12-year University of Pittsburgh study. Moreover, the study’s findings call into question the long-held belief that has shaped prevention efforts and governmental policy for six decades and caused many a parent to panic upon discovering a bag of pot in their child’s bedroom.

The Pitt researchers tracked 214 boys beginning at ages 10-12, all of whom eventually used either legal or illegal drugs. When the boys reached age 22, they were categorized into three groups: those who used only alcohol or tobacco, those who started with alcohol and tobacco and then used marijuana (gateway sequence) and those who used marijuana prior to alcohol or tobacco (reverse sequence).

Nearly a quarter of the study population who used both legal and illegal drugs at some point — 28 boys — exhibited the reverse pattern of using marijuana prior to alcohol or tobacco, and those individuals were no more likely to develop a substance use disorder than those who followed the traditional succession of alcohol and tobacco before illegal drugs, according to the study, which appears in this month’s issue of the American Journal of Psychiatry.

“The gateway progression may be the most common pattern, but it’s certainly not the only order of drug use,” said Ralph E. Tarter, Ph.D., professor of pharmaceutical sciences at the University of Pittsburgh School of Pharmacy and lead author of the study. “In fact, the reverse pattern is just as accurate for predicting who might be at risk for developing a drug dependence disorder.”

In addition to determining whether the gateway hypothesis was a better predictor of substance abuse than competing theories, the investigators sought to identify characteristics that distinguished users in the gateway sequence from those who took the reverse path. Out of the 35 variables they examined, only three emerged to be differentiating factors: Reverse pattern users were more likely to have lived in poor physical neighborhood environments, had more exposure to drugs in their neighborhoods and had less parental involvement as young children. Most importantly, a general inclination for deviance from sanctioned behaviors, which can become evident early in childhood, was strongly associated with all illicit drug use, whether it came in the gateway sequence, or the reverse.

While the gateway theory posits that each type of drug is associated with certain specific risk factors that cause the use of subsequent drugs, such as cigarettes or alcohol leading to marijuana, this study’s findings indicate that environmental aspects have stronger influence on which type of substance is used. That is, if it’s easier for a teen to get his hands on marijuana than beer, then he’ll be more likely to smoke pot. This evidence supports what’s known as the common liability model, an emerging theory that states the likelihood that someone will transition to the use of illegal drugs is determined not by the preceding use of a particular drug but instead by the user’s individual tendencies and environmental circumstances.

“The emphasis on the drugs themselves, rather than other, more important factors that shape a person’s behavior, has been detrimental to drug policy and prevention programs,” Dr. Tarter said. “To become more effective in our efforts to fight drug abuse, we should devote more attention to interventions that address these issues, particularly to parenting skills that shape the child’s behavior as well as peer and neighborhood environments.”

Indeed, according to the study, interventions focusing on behavior modification may be more effective prevention tactics than current anti-drug initiatives. For example, providing guidance to parents — particularly those in high-risk neighborhoods — on how to boost their caregiving skills and foster bonding with their children, could have a measurable effect on a child’s likelihood to smoke marijuana. Also, early identification of children who exhibit antisocial tendencies could allow for interventions before drug use even begins.

Although this research has significant implications for drug abuse prevention approaches, Dr. Tarter notes that the study has some limitations. First, as only male behaviors were studied, further investigation should explore if the results apply to women as well. Also, the examination of behaviors in phases beyond alcohol and marijuana consumption in the gateway series will be necessary.

Other study authors include Michael Vanyukov, Ph.D., and Maureen Reynolds, Ph.D., and Levent Kirisci, Ph.D., also of the University of Pittsburgh School of Pharmacy; and Duncan Clark, M.D., Ph.D., of the University of Pittsburgh School of Medicine. The research was funded by the National Institute on Drug Abuse.”

http://www.sciencedaily.com/releases/2006/12/061204123422.htm

Can Marijuana really be used to treat obesity?

“Some of you may read that title and are subconsciously checking off another reason why pot is fucking awesome. Good for you, the perception of marijuana as  an illicit substance has been changing steadily over the course of the decades. Several opinion polls now indicate that a majority of Americans now support the legalization of marijuana, conclusively proving that people like to get high.

Aside from getting high and playing Xbox live, it now appears that marijuana use may actually reduce the likelihood of obesity in individuals who smoke pot regularly. According to a study recently published in the American Journal of Epidemiology, regular users of cannabis have a much lower prevalence of obesity than non users. Even when the researchers adjusted for other factors that can contribute to body fat such as tobacco use, age or gender, the correlation remained strong.”

Read more:http://scallywagandvagabond.com/2013/05/can-marijuana-really-be-used-to-treat-obesity/

Study: Why Pot Smokers Are Skinnier

“Marijuana users had smaller waists and scored higher across several measures of blood sugar regulation.”
 
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“”Marijuana use is associated with an acute increase in caloric intake,” goes the clinical jargon for popular lore. Still despite eating more while high (by some measures, over 600 extra calories per day), marijuana users’ extra intake doesn’t seem to be reflected in increased BMI. Indeed, studies have identified a reduced prevalence of obesity in the pot smoking community…
 

IMPLICATIONS: Although they’re not sure exactly how it happens, write the authors, these findings suggest that marijuana somehow works to improve insulin control, regulating body weight and perhaps explaining why marijuana users have a lower incidence of diabetes. Adding to the big questions — “can weed can treat obesity?” and “marijuana makes you skinny?!” — is the possibility that marijuana might be useful in helping people to manage their blood sugar.”

Read more: http://www.theatlantic.com/health/archive/2013/05/study-why-pot-smokers-are-skinnier/275846/