“Recent research found that a liquid form of therapeutic marijuana can provide cure to children with treatment-resistant epilepsy.
The said study will be presented at the American Academy of Neurology’s 67th Annual Meeting in Washington, DC in late April.”
http://au.ibtimes.com/medicinal-marijuana-may-help-cure-children-severe-epilepsy-1440398
“Parkinson’s disease (PD) is a slow insidious neurological disorder characterized by a loss of dopaminergic neurons in the midbrain. Although several recent preclinical advances have proposed to treat PD, there is hardly any clinically proved new therapeutic for its cure.
Increasing evidence suggests a prominent modulatory function of the cannabinoid signaling system in the basal ganglia. Hence, use of cannabinoids as a new therapeutic target has been recommended as a promising therapy for PD.
The elements of the endocannabinoid system are highly expressed in the neural circuit of basal ganglia wherein they bidirectionally interact with dopaminergic, glutamatergic, and GABAergic signaling systems.
As the cannabinoid signaling system undergoes a biphasic pattern of change during progression of PD, it explains the motor inhibition typically observed in patients with PD.
Cannabinoid agonists such as WIN-55,212-2 have been demonstrated experimentally as neuroprotective agents in PD, with respect to their ability to suppress excitotoxicity, glial activation, and oxidative injury that causes degeneration of dopaminergic neurons.
Additional benefits provided by cannabinoid related compounds including CE-178253, oleoylethanolamide, nabilone and HU-210 have been reported to possess efficacy against bradykinesia and levodopa-induced dyskinesia in PD.
Despite promising preclinical studies for PD, use of cannabinoids has not been studied extensively at the clinical level. In this review, we reassess the existing evidence suggesting involvement of the endocannabinoid system in the cause, symptomatology, and treatment of PD. We will try to identify future threads of research that will help in the understanding of the potential therapeutic benefits of the cannabinoid system for treating PD.”
http://www.ncbi.nlm.nih.gov/pubmed/25888232
“To conclude, development of safe, effective cannabis-based medicines targeting different mechanisms may have a significant impact in PD therapy.”
Full-text: http://www.molecularneurodegeneration.com/content/10/1/17
http://www.thctotalhealthcare.com/category/parkinsons-disease/
“Cannabigerol (CBG) is a safe non-psychotropic Cannabis-derived cannabinoid which interacts with specific targets involved in carcinogenesis…
Here, we investigated whether CBG protects against colon tumorigenesis.
In vivo, CBG inhibited the growth of xenograft tumors as well as chemically-induced colon carcinogenesis.
CBG hampers colon cancer progression in vivo and selectively inhibits the growth of colorectal cancer cells, an effect shared by other TRPM8 antagonists.
CBG should be considered translationally in colorectal cancer prevention and cure.”
“Can Medical Cannabis Help to Cure SCD?”
“Sickle cell disease (SCD) is a hereditary condition caused by a mutation in the haemoglobin gene, which leads to symptoms of anaemia, extreme pain, and organ damage if unmanaged.”
“Individuals suffering from SCD are far more likely to use cannabis than the general population, potentially for its analgesic properties.
In 2010, researchers at the University of Minnesota found that the synthetic THC analogue CP 55,940 was as effective as morphine sulphate in treating SCD-related severe pain in transgenic mice expressing human sickle haemoglobin, and that it was effective at smaller doses than the opioid.
In 2011, a further paper submitted by the same researchers to Blood (the Journal of the American Association of Hematology) indicated that CP 55,940 ameliorated severe pain associated with the hypoxia/reoxygenation cycle. CP 55,940 is a full agonist of both CB receptors, and is thought to act as an antagonist at the GPR55 receptor.
As well as this, cannabis has been repeatedly shown to act as a vasodilator, which could in itself assist in easing the blockages caused by build-up of sickle cells…
SCD is a painful and debilitating disease, and the overall inefficacy of opioid treatments and resultant poor quality of life for many sufferers is an indication that our approach to it is far from perfect.
If cannabis is a good candidate to replace opioids, it should be implemented forthwith to prevent ongoing suffering for existing patients.”
http://sensiseeds.com/en/blog/sickle-cell-pain-may-managed-cannabis/
“Shona Banda was diagnosed with Crohn’s disease… She underwent several surgeries and was put on several pharmaceuticals, but her condition worsened progressively until she was considered terminal. She was bedridden… wasting away… She was waiting to die.
She managed to see Rick Simpson’s Run from the Cure…”
“Although she had been smoking marijuana to ease pain and help her sleep and eat, she had no way of making the oil, which required a pound of marijuana to produce the two ounces of cannabis oil she would need to heal.
Shona was in a funk about the lack of enough hemp to make her own oil when her husband noticed specks of oil residue in the inside of the vaporizer’s glass globe cover.
So she took the inhalation tube out of the vaporizer and sealed it, then simply collected those little blobs of oil from the inside of the glass globe with a spatula.
She did this three times a day, putting the collected oil residue into a capsule and taking it. After a very few days, Shona could walk without a cane. Soon she began eating and sleeping better and putting on weight. It wasn’t long before she was completely weened off all her pharmaceuticals.
She started a journal as she began getting better. The journal has become a book called Live Free or Die. The title is a reference to health freedom. Now she is very healthy and active.”
http://www.naturalnews.com/043718_chrons_disease_cannabis_shona_banda.html
“Ben Swann Radio: Shona Banda Explains Her Remarkable Story On How Cannabis Oil Saved Her Life. After being diagnosed with Crohn’s disease in 2002, Shona Banda went through the struggles that many suffer with when battling the autoimmune disease. On the Ben Swann Radio Show, Ben and Shona discussed her tribulations while suffering from the disease and her immediate experiences after finding the cure to her disease.”
http://benswann.com/ben-swann-radio-shona-banda-explains-her-remarkable-story-on-how-cannabis-oil-saved-her-life/#ixzz32d6WqrPM
https://www.facebook.com/shona.banda
https://www.facebook.com/pages/Shona-Bandas-Live-Free-or-Die/146496222049591
http://www.thctotalhealthcare.com/category/crohns-disease/
“Scientists are looking at the potential use of cannabis to treat and potentially cure severe forms of epilepsy.
The medical benefits of medical marijuana for neurological conditions like epilepsy are highly debated.
Examining the potential use of the drug, a series of articles in the journal Epilepsia, a journal of the International League Against Epilepsy, looks at its potential use for treating the syndrome.
Edward Maa, from the Comprehensive Epilepsy Program at Denver Health in Denver, Colorado, looks at a case study of a child with Dravet syndrome – a very severe form of epilepsy.
In the case, a mother provided her child with a strain of medical marijuana high in Cannabidiol (CBD) and tetrahydrocannabinol (THC) known as Charlotte’s Web.
When used with the child’s normal drug regime, seizures dropped from 50 convulsions per day to just two or three per month.”
http://www.thctotalhealthcare.com/category/dravet-syndome/
“Only until recently has medical marijuana received its deserved accolades by the mainstream media as a miracle drug; however, many in the medical industry are still leaving pot on the back-burner….until NOW.
A Canadian mother named Sarah Wilkinson has tangible claims about how cannabis has saved her disabled and once terminally ill daughter’s life.”
During an interview with the Toronto Sun, Wilkinson said “I assumed people who wanted it just wanted to get high” prior to her daughter’s marijuana use. However, once administering marijuana to her daughter with no other options from the pharmaceutical industry, Mia’s seizures went from 100 a day to 8 at most, changing her stance about the drug overnight. Results upon using the herb were immediate. Mia’s seizures ended within 24 hours of using the herb and now the Wilkinson’s don’t hesitate to call the drug a miracle.”
http://www.prweb.com/releases/2014/05/prweb11808330.htm
“Medical marijuana gives epileptic child new lease on life” http://www.torontosun.com/2014/04/26/medical-marijuana-gives-epileptic-child-new-lease-on-life
“It is even more evidence of our need for the government to stop punishing patients for using this relatively safe and non-toxic treatment method … ”
“For years, many Americans with HIV/AIDS have used medical marijuana to relieve some common symptoms associated with the illness such as nausea, vomiting and appetite loss.
Now, a new study published last week in the journal AIDS Researcher and Human Retroviruses found that a daily dosage of marijuana’s psychoactive ingredient tetrahydrocannabinol, or THC, may actually fight the HIV/AIDS virus itself.”
More: http://www.mintpressnews.com/hivaids-cure-may-be-found-in-marijuana-study/179398/
“Recently a 5-year-old child was administered a medical marijuana card, the youngest person to ever receive one. Her parents are nothing less than ecstatic, as this drug has worked wonders to reduce the amount and severity of her chronic, life-threatening epileptic seizures. This new found use for the highly controversial drug has been the reason for much debate, as well as hundreds of families deciding to relocate to Colorado, where marijuana is accessible to children to cure epileptic seizures…”
More: http://guardianlv.com/2014/02/marijuana-accessible-to-children-as-a-cure-for-epileptic-siezures/
“Kaercher said no matter what treatments Grace is on, the seizures continue. She has tried every option except medical marijuana, which isn’t legal in Pennsylvania,
Kaercher said. “Marijuana isn’t that extreme compared to all these other things we have done,” Kaercher said. Kaercher, 45, has watched her daughter suffer from seizures since Grace was a baby. Kaercher said Grave is so brave for going out into the world every day and her heart breaks every time Grace has a seizure.“It’s been a long road for us,” Kaercher said. “We hope medical marijuana will be a viable option for her.””