Cannabinoids Attenuate Cancer Pain and Proliferation in a Mouse Model

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“Oral cancer represents 3% of all cancers and its overall survival rate of 50% places it among the worst of all cancers

For many years cannabinoids have been used for medicinal and recreational purposes.

Recently, studies have focused on the therapeutic effects of cannabinoids on different cancers. The current study was the first to investigate the therapeutic effects of synthetic cannabinoids on oral cancer.

We investigated the effects of cannabinoid receptor agonists on (1) oral cancer cell viability in vitro and (2) oral cancer pain and tumor growth in a mouse cancer model.

Here we demonstrate the anti-nociceptive and anti-proliferative effects of systemic administration of cannabinoid receptor agonists on human oral cancer cells.

Our results suggest that systemic administration of cannabinoids decease oral cancer pain.

Our findings suggest a direct role for cannabinoid mechanisms in oral cancer pain and proliferation.

The systemic administration of cannabinoid receptor agonists may have important therapeutic implications wherein cannabinoid receptor agonists may reduce morbidity and mortality of oral cancer.

The present findings suggest that cannabinoid treatment may be a promising alternative therapy for oral cancer pain management. Furthermore, CBr2 agonism is not only palliative, but it may also be effective in inhibiting oral cancer growth, making the agonist a particularly desirable therapeutic agent.”

Full Text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3099480/

Evidence: Cannabinoid Therapy Reduces Breast Cancer Tumors

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“Warning: Many alternative treatments are shams with zero proof. Most alternatives make claims that are not backed up by any evidence or hard empirical medical studies, are are not peer-reviewed. 
 
Peer review means your study and its claims will be vetted by a panel of the best doctors and other medical professionals in that field, for critical review. They will try to find fault in its methodology before publication and its recommendations for possible human treatment.
 
For any cannabis-based study strong enough to stand up to this critical review, and for it to be published in a major journal within such a field as cancer research, is incredible. That’s exactly how strong the evidence for cannabis medicine is starting to become.
 
Imagine that. This plant, this “great friend of humanity” which has helped us survive by giving early humans food, fuel, fiber and medicine, and who ancient healers wrote about in 6000 B.C., more than 8,000 years ago, is now coming back to prove itself and to help save us again.
 
And this time we are starting to find the evidence to back up the claims made for this plant over the centuries…”
 

Tommy Chong is cancer-free

“Comedian and stoner icon TOMMY CHONG is celebrating after he was declared cancer-free. The Cheech & Chong star revealed last June (12) that he was suffering with stage one prostate cancer, but he decided against traditional medicine to treat the disease and instead opted to overhaul his diet and lifestyle.”

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 “Chong has now told fans he has overcome the cancer, and opened up about how he treated the condition.

In a blog post on CelebStoner.com, he writes, “After I came out with the news last June that a cancer doctor told me I had prostrate cancer and suggested a high frequency treatment that is not approved in America and could only be done in Mexico at the cost of $25,000, I immediately looked at alternatives. I contacted my nephew in Vancouver, who was about to become a doctor, and he suggested I meet with a Dr. McKinnon in Victoria, BC (British Columbia).

“That doctor changed my diet and put me on supplements, and within a year I brought my PSA (Prostate-Specific Antigen) numbers down drastically and eliminated the cancer threat. I also treated the condition with hemp oil (hash oil). With the diet, the supplements and the hash oil, plus a session with a world-renowned healer, Adam Dreamhealer, I’m cancer-free. That’s right, I kicked cancer’s a**! So the magic plant does cure cancer with the right diet and supplements. I’m due for another blood test, MRI, etc., but I feel the best I’ve felt in years.””

http://www.wptv.com/dpp/entertainment/celebrity/Tommy-Chong-is-cancerfree_42071723

Tommy Chong: ‘I’m Cancer-Free!’

Tommy Chong

“After I came out with the news last June that a cancer doctor told me I had prostrate cancer and suggested a high frequency treatment that is not approved in America and could only be done in Mexico at the cost of $25,000, I immediately looked at alternatives.

 I contacted my nephew in Vancouver, who was about to become a doctor, and he suggested I meet with a Dr. McKinnon in Victoria, BC. That doctor changed my diet and put me on supplements, and within a year I brought my PSA numbers down drastically and eliminated the cancer threat.

I also treated the condition with hemp oil (hash oil). With the diet, the supplements and the hash oil, plus a session with a world-renowned healer, Adam Dreamhealer, I’m cancer-free.

That’s right, I kicked cancer’s ass!

So the magic plant does cure cancer with the right diet and supplements. I’m due for another blood test, MRI, etc., but I feel the best I’ve felt in years. And now for a celebration joint of the finest Kush…”

http://www.celebstoner.com/blogs/tommy-chong/2013/05/06/tommy-chong-im-cancer-free!/

Tommy Chong Credits Marijuana For Cancer Cure, ‘I Kicked Cancer’s Ass!’ With ‘Hash Oil’

“A comedian who based his career off the reefer says it saved his life. Tommy Chong from the comedy duo “Cheech and Chong” says marijuana cured his prostate cancer.”

Chong

“Last week, Tommy Chong posted on CelebStoner that hemp oil helped him beat prostate cancer. The 74-year-old comedian added that the marijuana-based product used in conjunction with a supplemental diet and a session with a “world-renowned” healer brought his cancer threat down.

“That’s right, I kicked cancer’s ass! So the magic plant does cure cancer with the right diet and supplements,” Chong wrote.

Chong was diagnosed with prostate cancer last June. According to his post, Chong said he was recommended an intense treatment in Mexico, which cost $25,000. He sought an alternative and found a Canadian doctor who recommended a different diet and “hash oil.”

“I’m due for another blood test, MRI, etc., but I feel the best I’ve felt in years. And now for a celebration joint of the finest Kush,” Chong wrote.

Chong has advocated for the legalization of marijuana in the United States. He thinks that legalizing pot on a federal level would alleviate the country’s economic woes.”

More: http://www.ibtimes.com/tommy-chong-credits-marijuana-cancer-cure-i-kicked-cancers-ass-hash-oil-1264243

Marijuana mouth spray for cancer patients tough to abuse – NBC

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“The medical marijuana drug Sativex, which could be approved in the United States in the coming years as a treatment for pain relief, has little potential for abuse, experts say.

The British pharmaceutical company GW Pharmaceuticals is currently testing the drug, which is delivered as a mouth spray and called Sativex, in clinical trials. The company plans to seek U.S. Food and Drug Administration approval for the drug as a treatment for cancer pain when the trials are completed, likely sometime in 2014, a spokesperson for GW Pharmaceuticals told MyHealthNewsDaily.

The active ingredients in Sativex, known as cannabinoids, are derived from the cannabis plant. It is the first marijuana-based drug to be made by extracting the compounds from the plant, rather than synthesizing them. Two other drugs, Marinol and Cesamet, based on synthetic cannabinoids, were approved by the FDA in the 1980s.”

More: http://vitals.nbcnews.com/_news/2012/01/31/10280678-marijuana-mouth-spray-for-cancer-patients-tough-to-abuse?lite

Medical Cannabis Treatment for Cancer and HIV/AIDS ?

“Benefits of Medical Cannabis”

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“Today, there are at least 17 states, including the District of Colombia, where cannabis is legal. Ohio, South Carolina, Colorado, New Jersey, California, and Michigan are just a few states that garnered strong support in the legalization of  medical cannabis. In Illinois, a bill legalizing the use of  cannabis needed the signature of Gov Pat Quinn. The legislation was approved by House and Senate, permitting doctors to prescribe cannabis for cancer and patients with HIV/AIDS and other diseases…

There is now quantifiable evidence that cannabis is beneficial in treating many disorders…

Moreover, the Medical Cannabis Research and the University of California found out that cannabis can treat HIV/AIDS and multiple sclerosis symptoms. It can even benefit cancer patients to mitigate the unpleasant side effects of chemotherapy or as an alternative treatment for cervical cancer, breast cancer, prostate cancer, lung cancer, colorectal cancer, brain cancer, and leukemia.”

More: http://guardianlv.com/2013/05/medical-cannabis-treatment-for-cancer-and-hivaids/

Cannabis Science Reports Cancer Tumors Continues to Shrink and Die as Apparent Pieces of the Dying Cancer Tumors Begin to Fall off as Evidenced in Newest Photos of the 3rd Squamous Cell Carcinoma Patient

“Cannabis Science, Inc. a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is pleased to release new updated photos from the 3rd cancer patient self-administering cannabis extracts. This patient has severe squamous cell carcinoma on their head that was resistant to chemo and radiation therapy, which left the patient with large tumor masses on their head. With these new photo updates you can see the drastic change in appearance of the tumors and how the topical cannabis extract is killing them. 

Cannabis Science has been working very closely with this patient and is continuing to see vast improvement to his treatment resistant squamous cell carcinoma. Prior to using cannabis-based extracts this patient had received radiation and chemotherapy for his condition. This patient notices a huge difference between the treatments and had stated, “While on radiation treatments, each day was stressful and after each treatment I felt horrible as if my entire body was dying organ by organ. While using the Oil, I have noticed that my overall health seems much better. I sleep the recommended hours, unlike the insomnia I suffered while on radiation, and unlike the radiation that caused the restless sleep and nightmares, on the Oil I sleep like a baby.” The patient also mentioned that while showering they would see bits and pieces of the tumor falling off with the water as he was cleaning his head.

This patient is very pleased with the results of the topical cannabis extract so far and said he enjoyed absolutely nothing about radiation and felt constantly sick and just overall unhealthy, but with using the oil he said, “I feel myself being restored, not tortured.””

More: http://www.drugs.com/clinical_trials/cannabis-science-reports-cancer-tumors-continues-shrink-die-apparent-pieces-dying-cancer-tumors-13168.html

Cannabis says success in 4th brand new self-administering cancer patient

“Cannabis Science Inc., a pioneering US biotech company developing pharmaceutical cannabis (marijuana) products, has introduced 4th cancer patient with basal cell carcinoma (skin cancer) on his left nostril, who is self-administering a topical cannabis extract and having noticeable results.

Cannabis Science has received images and documented information from this 4th patient who has basal cell carcinoma on his left nostril. The patient is enrolled in a photographic mole-mapping programme at the University of Colorado Hospital and is examined annually. The last time he was examined was in October of 2011, where his doctors found a small bump on his left nostril that was less and 1/8″ in diameter, and believed it to be basal cell carcinoma. At that time it was too early to be certain if it was in-fact basal cell carcinoma.

By January 2012 the small bump on his left nostril had grown slightly and had developed a rough scaly texture similar to his previous episodes of basal cell carcinoma. The patient began self-administering cannabis extract oil (CT-1) topically to the spot on his left nostril in the middle of January. The patient immediately reported minor irritation of the spot but that the surrounding healthy skin was not irritated. The rough scaly texture and the minor irritation disappeared by day four of treatment and by day nine of treatment the bump had shrunk considerably and was almost imperceptible to the touch. In these three images you can notice a significant reduction in the lesion.

This patient has a history of having five different episodes of basal cell carcinoma starting at the age of 27, and had one malignant melanoma at age 35. He is now 46, and has suffered from numerous severe sunburns which caused blistering and peeling. This patient was diagnosed with dysplastic nevus syndrome (over 100 atypical moles) and has been told that he is certain to have additional melanomas at some point in the future. Doctors have already confirmed that he has had basal cell carcinoma on his right jaw line, which resulted to Mohs procedure that was performed in December of 2011.

Cannabis Science, Inc. is at the forefront of pharmaceutical grade medical marijuana research and development. The second formulations will address the needs of patients choosing to use concentrated cannabis extracts to treat their ailments.

 Eventually, all Americans will have access to a safe and effective FDA approved medicine regardless of which state they live in.”

http://pharmabiz.com/NewsDetails.aspx?aid=67354&sid=2 

Physician’s documentation confirms successful treatment of basal cell carcinoma with topical cannabis extract

“We are pleased to announce that we have physician’s documentation that confirms the successful treatment of basal cell carcinoma that resulted from the application of a topical cannabis extract.” 

Currently, there is a tremendous amount of controversy with respect to the effects that cannabinoids have on cancers. Endocannabinoids, phytocannabinoids, and synthetic cannabinoids have demonstrated cancer killing and anti-metastatic properties in tissue culture and in animal models.

While formal, proper, FDA approved clinical trials that would prove or disprove the therapeutic potential of cannabis extracts for treating cancers; trials have not been carried out. Nevertheless, a significant number of anecdotal observations have accumulated that suggest people suffering from a variety of cancers appear to have been cured by ingesting what is known as “Rick Simpson’s hemp oil”.”

More: http://www.news-medical.net/news/20110407/Physicians-documentation-confirms-successful-treatment-of-basal-cell-carcinoma-with-topical-cannabis-extract.aspx