“The cultivation of four industrial hemp cultivars (Felina 32, Chamaeleon, Uso31, and Finola) was investigated for oil production in the north-east of Italy along two years. The oils of all cultivars resulted in rich amount of linoleic acid (ω-6) and α-linolenic acid (ω-3). Felina 32 and Chamaeleon oils exhibited the highest amount of linoleic acid (59%) and α-linolenic acid (18%). Finola and Uso31 oils resulted in the richest of γ-linolenic acid (5-6%). All hempseed oils presented high oxidation stability and an acceptable initial quality. It is suggested that these oils can be used to produce EFA dietary supplements high in ω-6 and ω-3 of vegetal origin.”
Tag Archives: cannabis
Effects of Hemp (Cannabis sativa L.) Seed Oil Press-Cake and Decaffeinated Green Tea Leaves (Camellia sinensis) on Functional Characteristics of Gluten-Free Crackers.
“A mixture, simplex centroid, 2 components experimental design was used to evaluate the addition of hemp seed oil press-cake and decaffeinated green tea leaves, as functional ingredients to assess nutritional characteristics and antioxidant properties of gluten-free crackers.
All samples with added hemp flour had much better nutritional qualities than the brown rice flour crackers in terms of higher protein, crude fibers, minerals, and essential fatty acids content. Likewise, all samples with added decaffeinated green tea leaves had much better antioxidant properties than crackers with no added green tea leaves. All crackers with added hemp flour had a significantly increased fiber content (39% to 249%) and decreased carbohydrate content (8.4% to 42.3%), compared to the brown rice flour crackers.
All samples had antioxidant properties, even without the addition of green tea leaves.
Optimization of the responses was conducted based on the maximized values for protein, fibers, omega-3 fatty acids content, as well as for the antioxidant activity and overall score. The suggested values for the addition of the hemp oil press-cake was 20% (total flour weight) with 4 g of decaffeinated green tea leaves that would provide protein content of 14.1 g/100 g; fibers content of 8.4 g/100 g; omega-3 fatty acids content of 3.2 g/100 g; antioxidant activity measured via 2,2-diphenyl-1-picrylhydrazyl value of 30.3 μmol TE/g d.w.; and an overall score of 8.9.
This formulation has demonstrated potential application in the baking industry and marketing of these gluten-free crackers as a value-added functional product.”
Anticoagulant effects of a Cannabis extract in an obese rat model.
“Blood coagulation studies were conducted to determine the possible anti-/prothrombotic effect of an organic cannabis extract and the three major cannabinoids, THC, CBD and CBN…
The study thus shows that Cannabis sativa and the cannabinoids, THC and CBN, display anticoagulant activity and may be useful in the treatment of diseases such as type 2 diabetes in which a hypercoagulable state exists.”
Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract.
“Cannabis is widely used for treating a number of gastrointestinal ailments…
In the present study, we tested the effects (in rats) of a simple extract of medicinal cannabis (called “MFF”) for its ability to promote resolution of colitis…
These results demonstrate that a simple extract of medicinal cannabis can significantly enhance resolution of inflammation and injury, as well as prevent injury, in the gastrointestinal tract. Interestingly, different cannabinoid receptors were involved in some of the effects. MFF may serve as the basis for a simple preparation of cannabis that would produce beneficial effects in the GI tract with reduced systemic toxicity.”
Mom looks to medical marijuana to cure daughter’s seizures
“Kaercher said no matter what treatments Grace is on, the seizures continue. She has tried every option except medical marijuana, which isn’t legal in Pennsylvania,
Kaercher said. “Marijuana isn’t that extreme compared to all these other things we have done,” Kaercher said. Kaercher, 45, has watched her daughter suffer from seizures since Grace was a baby. Kaercher said Grave is so brave for going out into the world every day and her heart breaks every time Grace has a seizure.“It’s been a long road for us,” Kaercher said. “We hope medical marijuana will be a viable option for her.””
The Neuroscience Of Munchies: Why The Scent Of A Burger Gives Us A High – npr
“From cinnamon buns in the morning to a burger after a long run, food never smells as good as when you’re superhungry.
Now scientists have uncovered a clue as to why that might be — and it lies in the munchies and marijuana.
Receptors in the brains of mice that light up when the animals are high are also activated when the critters are fasting, French scientists reported Sunday in the journal Nature Neuroscience.
In other words, skipping a meal triggered the same hunger-inducing brain receptors that marijuana does. And it works, at least in mice, by boosting the sense of smell, neuroscientist Giovanni Marsicano and his team at the Universite de Bordeaux report.
That’s because the receptors that get activated are located in the smelling center of the brain. And sense of smell is known to be a key factor driving appetite.
In case you’re wondering, the mice didn’t toke up. The researchers injected the rodents withTHC, the active ingredient in marijuana.”
“The endocannabinoid system controls food intake via olfactory processes.” http://www.ncbi.nlm.nih.gov/pubmed/24509429
Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling.
“Although pain is multifactorial at cellular and molecular levels, it is widely accepted that neurotrophin (TrkA, p75NTR, Ret and GFRs), cannabinoid (CB1 and CB2), and thermo-transient receptor potential (TRPs; TRPV1, TRPA1 and TRPM8) receptors play a pivotal role.
…the available information confirms that pharmacological modulation of this signalling triad is a highly valuable therapeutic strategy for effectively treating pain syndromes.”
Cannabis extract treatment for terminal acute lymphoblastic leukemia with a Philadelphia chromosome mutation.
” This case study is on a 14-year-old patient diagnosed with a very aggressive form of ALL (positive for the Philadelphia chromosome mutation). A standard bone marrow transplant, aggressive chemotherapy and radiation therapy were revoked, with treatment being deemed a failure after 34 months.
Without any other solutions provided by conventional approaches aside from palliation, the family administered cannabinoid extracts orally to the patient.
Cannabinoid resin extract is used as an effective treatment for ALL with a positive Philadelphia chromosome mutation and indications of dose-dependent disease control.
The clinical observation in this study revealed a rapid dose-dependent correlation.”
Effect of cannabinoid receptor activation on spreading depression.
“Cannabis has been used for centuries for both symptomatic and prophylactic treatment of different types of headaches including migraine…
Suppression of CSD (cortical spreading depression) by activation of CB1 receptors suggests the potential therapeutic effects of cannabinoids in migraine with aura as well as other CSD-related disorders.”
Using cannabis to help you sleep: Heightened frequency of medical cannabis use among those with PTSD.
“The use of cannabis for medical purposes is proliferating in the U.S., and PTSD is an explicitly approved condition for accessing medical cannabis in 5 states. Prior research suggests that people with PTSD often use cannabis to help cope with their condition…
Those with high PTSD scores were more likely to use cannabis to improve sleep, and for coping reasons more generally, compared with those with low PTSD scores. Cannabis use frequency was greater among those with high PTSD scores who used for sleep promoting purposes compared with those with low PTSD scores or those who did not use for sleep promoting purposes.
Consistent with prior research, this study found increased rates of coping-oriented use of cannabis and greater frequency of cannabis use among medical users with high PTSD scores compared with low PTSD scores. In addition, sleep improvement appears to be a primary motivator for coping-oriented use…”