Marijuana Ingredient Inhibits VEGF Pathway Required For Brain Tumor Blood Vessels

“Cannabinoids, the active ingredients in marijuana, restrict the sprouting of blood vessels to brain tumors by inhibiting the expression of genes needed for the production of vascular endothelial growth factor (VEGF).

“Blockade of the VEGF pathway constitutes one of the most promising antitumoral approaches currently available,” said Manuel Guzmán, professor of biochemistry and molecular biology, with the Complutense University in Madrid, Spain, and the study’s principal investigator.

“The present findings provide a novel pharmacological target for cannabinoid-based therapies.””

More: http://www.sciencedaily.com/releases/2004/08/040816085401.htm

“Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas.” http://cancerres.aacrjournals.org/content/64/16/5617.long

Inhibition of tumor angiogenesis by cannabinoids

“Cannabinoids, the active components of marijuana and their derivatives, inhibit tumor growth in animal models… Because the generation of a new vascular supply (angiogenesis) is causally involved in the progression of the majority of solid tumors, the aim of this study was to test whether cannabinoids inhibit tumor angiogenesis.”

Figure 1.

“PRINCIPAL FINDINGS

1. Cannabinoid administration inhibits tumor angiogenesis

2. Cannabinoid administration inhibits vascular endothelial cell migration and survival

3. Cannabinoid administration inhibits tumor expression of proangiogenic factors and improves other markers of tumor malignancy

 

 …In the context of the renaissance in the study of the therapeutic effects of cannabinoids, our findings show that these compounds may be considered promising anti-tumoral agents as they inhibit tumor angiogenesis and growth in vivo with no significant side effects.

 This report provides a mechanistic basis for the anti-tumoral action of cannabinoids and a novel pharmacological target for cannabinoid-based anti-tumoral therapies…”

Full text:  http://www.fasebj.org/content/17/3/529.full

The use of cannabinoids in chronic pain.

“We present the case of a 56-year-old man who developed chronic pain following the excision of a facial cancer that was poorly controlled despite multiple analgesic medications. Following the starting of nabilone (a synthetic cannabinoid) his pain control was greatly improved and this had a huge impact on his quality of life.

We also managed to significantly reduce his doses of opioid analgesia and ketamine.

We review the current literature regarding the medicinal use of cannabinoids, with an emphasis on chronic pain, in an attempt to clarify their role and how to select patients who may benefit from this treatment.”

http://www.ncbi.nlm.nih.gov/pubmed/23893276

From here to eternity – the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond

“From here to eternity – the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583426/

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“Anticarcinogenic effects of some Indian plant products.” http://www.ncbi.nlm.nih.gov/pubmed/1473788

“Plant products as protective agents against cancer.” http://www.ncbi.nlm.nih.gov/pubmed/2283166

“Potential of spice-derived phytochemicals for cancer prevention.” http://www.ncbi.nlm.nih.gov/pubmed/18612945

“Antimicrobial and chemopreventive properties of herbs and spices.” http://www.ncbi.nlm.nih.gov/pubmed/15180577

“Antioxidant activity and protecting health effects of common medicinal plants.” http://www.ncbi.nlm.nih.gov/pubmed/23034115

“Chemopreventive effects of Cuminum cyminum in chemically induced forestomach and uterine cervix tumors in murine model systems.” http://www.ncbi.nlm.nih.gov/pubmed/15087270

“Cancer cell signaling pathways targeted by spice-derived nutraceuticals.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645308/

“Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes with anti- hepatocarcinogenic effects.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364896/

“A long-term investigation of the anti-hepatocarcinogenic potential of an indigenous medicine comprised of Nigella sativa, Hemidesmus indicus and Smilax glabra” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475831/

“[Anti-metastasis effect of thymoquinone on human pancreatic cancer]… thymoquinone (TQ), a component derived from the medicinal spice Nigella sativa (also called black cumin)” http://www.ncbi.nlm.nih.gov/pubmed/22007514

“Thymoquinone suppresses metastasis of melanoma cells by inhibition of NLRP3 inflammasome… our results indicate that thymoquinone can be a potential immunotherapeutic agent not only as an adjuvant therapy for melanoma, but also, in the control and prevention of metastatic melanoma.” http://www.ncbi.nlm.nih.gov/pubmed/23583630

“Anti-inflammatory effects of the Nigella sativa seed extract, thymoquinone, in pancreatic cancer cells” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742606/

“Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.” http://www.ncbi.nlm.nih.gov/pubmed/15375533

“Structure-Activity Studies on Therapeutic Potential of Thymoquinone Analogs in Pancreatic Cancer” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093961/

“Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and ERK signaling pathways” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587125/

“Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909169/

“Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and thymoquinone on colon cancer cells.”  http://www.ncbi.nlm.nih.gov/pubmed/16817633

“Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein.” http://www.ncbi.nlm.nih.gov/pubmed/21609759

“Thymoquinone: potential cure for inflammatory disorders and cancer.” http://www.ncbi.nlm.nih.gov/pubmed/22005518

“Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma.” http://www.ncbi.nlm.nih.gov/pubmed/21215312

“Anti-cancer effects of thymoquinone in mouse neuroblastoma (Neuro-2a) cells through caspase-3 activation with down-regulation of XIAP.” http://www.ncbi.nlm.nih.gov/pubmed/22732633

“Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.” http://www.ncbi.nlm.nih.gov/pubmed/21679698

“Antineoplastic and apoptotic potential of traditional medicines thymoquinone and diosgenin in squamous cell carcinoma.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471895/

“Antineoplastic effects of bee honey and Nigella sativa on hepatocellular carcinoma cells.” http://www.ncbi.nlm.nih.gov/pubmed/21147814

“Antitumor and anti-angiogenesis effects of thymoquinone on osteosarcoma through the NF-κB pathway.” http://www.ncbi.nlm.nih.gov/pubmed/23232982

“Antiproliferative properties of methanolic extract of Nigella sativa against the MDA-MB-231 cancer cell line.” http://www.ncbi.nlm.nih.gov/pubmed/23317266

“Methanolic extract of Nigella sativa seed inhibits SiHa human cervical cancer cell proliferation through apoptosis… could potentially be an alternative source of medicine for cervical cancer therapy.”  http://www.ncbi.nlm.nih.gov/pubmed/23513732

“Plant crude extracts could be the solution: extracts showing in vivo antitumorigenic activity.” http://www.ncbi.nlm.nih.gov/pubmed/18390447

“Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carcinogenesis.” http://www.ncbi.nlm.nih.gov/pubmed/12881014

“Cancer chemopreventive potential of volatile oil from black cumin seeds, Nigella sativa L., in a rat multi-organ carcinogenesis bioassay.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436209/

“Effect of Nigella sativa (N. sativa L.) and oxidative stress on the survival pattern of MCF-7 breast cancer cells.” http://www.ncbi.nlm.nih.gov/pubmed/12724920

“The in vitro anti-tumor activity of some crude and purified components of blackseed, Nigella sativa L.” http://www.ncbi.nlm.nih.gov/pubmed/9673365

“Antitumour principles from Nigella sativa seeds.” http://www.ncbi.nlm.nih.gov/pubmed/1555206

“Anti-tumor properties of blackseed (Nigella sativa L.) extracts.” http://www.ncbi.nlm.nih.gov/pubmed/17581684

“Anticancer activity of Nigella sativa (black seed) – a review.” http://www.ncbi.nlm.nih.gov/pubmed/22083982

“Anticancer activities of Nigella sativa (black cumin).” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252704/

“ANTI-CANCER ACTIVITY OF NIGELLA SATIVA” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336718/

Curing With Curcumin – News

“Chemical in Tumeric, Popular in Curries, May Cut Colon Cancer”  http://www.foxnews.com/story/2006/08/02/chemical-in-tumeric-popular-in-curries-may-cut-colon-cancer/

“Curry may help in fight against bowel cancer, study finds” http://www.foxnews.com/health/2012/05/08/curry-may-help-in-fight-against-bowel-cancer-study-finds/

 “Researchers Uncover Why Turmeric Helps Heal” http://abcnews.go.com/Health/Healthday/story?id=7769316&page=1

“Healing powers of turmeric uncovered” http://abclocal.go.com/kabc/story?id=6854704

 “Curry spice used to fight bowel cancer” http://www.abc.net.au/news/2012-05-08/curry-may-fight-bowel-cancer/3997590

“Turmeric inhibits cancer’s spread in mice” http://www.abc.net.au/news/2005-06-10/turmeric-inhibits-cancers-spread-in-mice/1589900

“The Healing Power Of Curry?” http://www.cbsnews.com/video/watch/?id=2681428n

“Curry May Cut Down Colon Cancer” http://www.cbsnews.com/2100-500368_162-1860248.html

“Seasonings That Help Your Health” http://www.cbsnews.com/2100-500165_162-799082.html

“Curry chemical’s ability to fight cancer put to the test” http://www.bbc.co.uk/news/health-17959521

“Curry spice ‘kills cancer cells'” http://news.bbc.co.uk/2/hi/health/8328377.stm

“Turmeric ‘Kills Cancer Cells'” http://www.huffingtonpost.com/2009/10/28/turmeric-kills-cancer-cel_n_336850.html

“Turmeric component kills cancer cells.” http://www.thefreelibrary.com/Turmeric+component+kills+cancer+cells.-a0123580388

“Scientists say curry compound kills cancer cells” http://www.abs-cbnnews.com/technology/10/28/09/scientists-say-curry-compound-kills-cancer-cells 
“Primary component in turmeric kicks off cancer-killing mechanisms in human saliva” http://medicalxpress.com/news/2011-09-primary-component-turmeric-cancer-killing-mechanisms.html

“Curcumin halts spread of breast cancer in mice – Early study shows spice stunts deadly spread to lungs” http://www.medicalnewstoday.com/releases/32147.php 

“How Curcumin Helps Fight Cancer” http://www.medicalnewstoday.com/releases/72129.php

“Curcumin Inhibits Prostate Cancer Metastases” http://www.medicalnewstoday.com/articles/251461.php

“Cancer Doctor Explains How Cooking with Turmeric Leads to Amazing Health Benefits” http://naturalsociety.com/cancer-doctor-explains-how-cooking-turmeric-health-benefits/

“Curry Spice Kills Cancer Cells” http://www.newser.com/story/72704/curry-spice-kills-cancer-cells.html

“Scientists say curry compound kills cancer cells” http://www.reuters.com/article/2009/10/28/us-cancer-curry-idUSTRE59R1E020091028

“Curcumin and melanoma. Can a spice help fight cancer?” http://health.usnews.com/usnews/health/briefs/cancer/hb050711a.htm

“Curry Spice May Fight Skin Cancer. Ingredient in Curry May Kill Melanoma Cells” http://www.webmd.com/cancer/news/20050711/curry-spice-fight-skin-cancer

“Curry compound could fight cancer; Curcumin may kill bowel cancer cells” http://www.nydailynews.com/life-style/health/curry-india-holy-powder-subject-cancer-fighting-proven-spice-curcumin-kill-bowel-cancer-cells-article-1.1074477

“Curcumin vs. cancer: The scientific evidence continues to flow in” http://www.naturalnews.com/039304_curcumin_cancer_scientific_evidence.html

“Curcumin and black pepper combine to stop breast cancer tumor cells” http://www.naturalnews.com/028763_cancer_tumors_curcumin.html

“Groundbreaking study: Aronia, curcumin extracts effectively kill brain cancer cell line” http://www.naturalnews.com/037476_aronia_curcumin_brain_cancer.html

“Curcumin slays cancer cells in their tracks” http://www.naturalnews.com/037879_curcumin_cancer_cells_turmeric.html

“Primary Component in Curry Spice Kicks Off Cancer-Killing Mechanisms in Human Saliva” http://www.sciencedaily.com/releases/2011/09/110913092430.htm

“Study: Chewing curcumin activates cancer-killing mechanisms” http://www.digitaljournal.com/article/311514

“Curry compound kills cancer cells” http://www.health24.com/Medical/Cancer/News/Curry-compound-kills-cancer-cells-20120721

 

Anti-cancer effects of curcumin (CUR) and tetrahydrocurcumin (THC) – Science

Curry Powder.jpg
 

“Anticancer potential of curcumin: preclinical and clinical studies.” http://www.ncbi.nlm.nih.gov/pubmed/12680238

“Tetrahydrocurcumin is more effective than curcumin in preventing… colon carcinogenesis. Tetrahydrocurcumin (THC), a major metabolite of curcumin (CUR), has been demonstrated to be anti-cancerogenic and anti-angiogenic…these results demonstrated for the first time the in vivo chemopreventive efficacy and molecular mechanisms of dietary THC…”  http://www.ncbi.nlm.nih.gov/pubmed/21887819

“Tetrahydrocurcumin inhibits HT1080 cell migration and invasion via downregulation of MMPs and uPA.” http://www.ncbi.nlm.nih.gov/pubmed/18565284

“Plant-derived anticancer agents – curcumin in cancer prevention and treatment.”  http://www.ncbi.nlm.nih.gov/pubmed/23700916

“Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701520/

“Mechanisms of cancer chemoprevention by curcumin.” http://www.ncbi.nlm.nih.gov/pubmed/11370761 

“Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.” http://www.ncbi.nlm.nih.gov/pubmed/21928294

 “Synergistic anticancer activity of curcumin and catechin: an in vitro study using human cancer cell lines.” http://www.ncbi.nlm.nih.gov/pubmed/21780253 

“Synergistic anticancer effects of curcumin and resveratrol in Hepa1-6 hepatocellular carcinoma cells.” http://www.ncbi.nlm.nih.gov/pubmed/23446753

“Curcumin enhances the anticancer effects of trichostatin a in breast cancer cells.” http://www.ncbi.nlm.nih.gov/pubmed/22290509

 “Curcumin polymers as anticancer conjugates.” http://www.ncbi.nlm.nih.gov/pubmed/20591475

“Curcumin Potentiates The Ability of Sunitinib to Eliminate the VHL-lacking Renal Cancer Cells 786-O: Rapid Inhibition of Rb Phosphorylation as a Preamble to Cyclin D1 Inhibition.” http://www.ncbi.nlm.nih.gov/pubmed/23848205

 “RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ER‑negative breast cancer models.” http://www.ncbi.nlm.nih.gov/pubmed/22971638

“ApoE3 mediated polymeric nanoparticles containing curcumin: apoptosis induced in vitro anticancer activity against neuroblastoma cells.” http://www.ncbi.nlm.nih.gov/pubmed/22890189

 “Inclusion complex of novel curcumin analogue CDF and β-cyclodextrin (1:2) and its enhanced in vivo anticancer activity against pancreatic cancer.” http://www.ncbi.nlm.nih.gov/pubmed/22322899

“Water-soluble antioxidants improve the antioxidant and anticancer activity of low concentrations of curcumin in human leukemia cells.” http://www.ncbi.nlm.nih.gov/pubmed/15700780

“Superior anticancer efficacy of curcumin-loaded nanoparticles against lung cancer.” http://www.ncbi.nlm.nih.gov/pubmed/23786839

“Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers.” http://www.ncbi.nlm.nih.gov/pubmed/21603867

“Apigenin shows synergistic anticancer activity with curcumin by binding at different sites of tubulin.” http://www.ncbi.nlm.nih.gov/pubmed/23485682

 “Anticancer and carcinogenic properties of curcumin: considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent.” http://www.ncbi.nlm.nih.gov/pubmed/18496811

“Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric.” http://www.ncbi.nlm.nih.gov/pubmed/23847105

“Perspectives on new synthetic curcumin analogs and their potential anticancer properties.” http://www.ncbi.nlm.nih.gov/pubmed/23116312

“Synthesis and evaluation of curcumin-related compounds for anticancer activity.” http://www.ncbi.nlm.nih.gov/pubmed/22551677

 “Curcumin and its analogues: potential anticancer agents.” http://www.ncbi.nlm.nih.gov/pubmed/20027668

“Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665575/

“Highly active anticancer curcumin analogues.” http://www.ncbi.nlm.nih.gov/pubmed/17569206 

Kurkumina

Health Benefits of Cannabis Tea

Health Benefits of Cannabis Tea 

 

“Reduces Chronic Pain

Reduces Anxiety

Reduces Nausea

May Treat Autoimmune Diseases”

“Marijuana-Infused Tea… Mom always said a cup of tea at night makes it easier to sleep.. Kevin Reed, of The Green Cross medical marijuana dispensary in San Francisco, advises patients to add a little milk after brewing to get the full effect of the cannabis.”  http://www.cbsnews.com/2300-204_162-10004358-12.html

 

“Cannabis Tea… Other names: Pot Tea, Weed Tea…Translations: Kaņepes Tēja, Kanapių arbata, Ceai de canabis, Kanabis Tea, Cần sa trà, Cannabis urządzenia, कैनबिस चाय, Chá de Cannabis, Каннабис чай, Η κάνναβη Τσάι, القنب الشاي, 대마초 차, Cannabis Čaj, Cannabis Teh, 大麻茶, Cannabis para preparar té, Cannabis Čaj, קנאביס תה, Канабис чај, 大麻コーヒー, Cannabis Te, Cannabis per a preparar te, Каннабіс чай, Kannabis Tea, Канабис чай”     http://www.foodista.com/food/3HJ8KNK6/cannabis-tea#

“Cannabis tea revisited: a systematic evaluation of the cannabinoid composition of cannabis tea.”   http://www.ncbi.nlm.nih.gov/pubmed/17604926

25 Benefits to Drinking Green Tea

Medicinal Cannabis Does Not Influence the Clinical Pharmacokinetics of Irinotecan and Docetaxel

“For the past 4,000 years, patients and doctors of each era have resorted to cannabis when conventional treatments were ineffective or lacking. Indeed, in oncology beneficial effects have been reported for cancer-associated anorexia, chemotherapy-induced nausea and vomiting, and palliation…

The only U.S. Food and Drug Administration (FDA)-approved medicinal cannabis products are an oral formulation containing dronabinol (Marinol®)… the synthetic version of delta9-tetrahydrocannabinol (THC), the main pharmacologically active cannabinoid, and capsules containing nabilone, an analog of dronabinol (Cesamet®)…

…many patients claim (subjectively) that a whole or partially purified extract of Cannabis sativa L. offers advantages over a single isolated ingredient…

We anticipated an increased use of medicinal cannabis concurrent with anticancer drugs, and undertook a drug-interaction study to evaluate the effect of concomitant medicinal cannabis on the pharmacokinetics of irinotecan and docetaxel…

Conclusion. Coadministration of medicinal cannabis, as herbal tea, in cancer patients treated with irinotecan or docetaxel does not significantly influence the plasma pharmacokinetics of these drugs. The evaluated variety of medicinal cannabis can be administered concomitantly with both anticancer agents without dose adjustments.”

Full text: http://theoncologist.alphamedpress.org/content/12/3/291.long

Scientists find how green tea fights cancer – News

 

“Scientists find how green tea fights cancer.
 

“Cup of Herbal Tea Could Help Fight Breast Cancer” http://www.sciencedaily.com/releases/2012/08/120824082506.htm

 

“25 Benefits to Drinking Green Tea… #1. Green tea and cancer: Green tea helps reduce the risk of cancer.” http://www.authintmail.com/news/science/health/25-benefits-drinking-green-tea

 

“Green Tea May Fight Lung Cancer” http://www.cbsnews.com/2100-500368_162-2558663.html

“Green Tea May Ward Off Lung Cancer” http://abcnews.go.com/Health/Wellness/green-tea-ward-off-lung-cancer/story?id=9575951

“How Green Tea May Thwart Lung Cancer” http://www.foxnews.com/health/2011/10/10/how-green-tea-may-thwart-lung-cancer-247062392/

“Green Tea Could Modify the Effect of Cigarette Smoking On Lung Cancer Risk” http://www.sciencedaily.com/releases/2010/01/100112165108.htm

 “Tea Ingredient Fights Leukemia” http://www.webmd.com/cancer/news/20050404/tea-ingredient-fights-leukemia

“Tea Ingredient Fights Leukemia” http://www.foxnews.com/story/0,2933,152447,00.html 

“Green Tea’s Cancer-Fighting Allure Becomes More Potent” http://www.sciencedaily.com/releases/2003/08/030805072109.htm

“Green tea fights oral cancer” http://healthnewsreport.blogspot.com/2009/11/green-tea-fights-oral-cancer.html

“Green Tea Fights Prostate Cancer” http://healthnewsreport.blogspot.com/2012/10/green-tea-fights-prostate-cancer.html

“Green tea fights inflammation and cancer.” http://www.examiner.com/article/green-tea-fights-inflammation-and-cancer

“Green tea fights cancer”  http://www.foodconsumer.org/newsite/Nutrition/Food/green_tea_fights_cancer_0514120548.html

“Green tea fights ovarian cancer” http://www.foodconsumer.org/newsite/2/Cancer/green_tea_fights_ovarian_cancer_0508120840.html

Green Tea’s Record Against Cancer Grows. Green Tea Extract Targets Cancer Without Hurting Healthy Cells” http://www.webmd.com/food-recipes/news/20050215/green-teas-record-against-cancer-grows

“Green Tea, White Tea Fight Colon Cancer” http://www.webmd.com/colorectal-cancer/news/20030311/green-tea-white-tea-fight-colon-cancer

“Could Green Tea Help Fight Prostate Cancer?” http://healthyliving.msn.com/nutrition/could-green-tea-help-fight-prostate-cancer

“Could Green Tea Help Fight Prostate Cancer?” http://health.usnews.com/health-news/news/articles/2012/10/18/could-green-tea-help-fight-prostate-cancer

“Drinking green tea may fight prostate cancer” http://www.nbcnews.com/id/22325869/ns/health-cancer/t/drinking-green-tea-may-fight-prostate-cancer/

“Green Tea Extract ‘Made Cancer Disappear’, Study Shows” http://www.huffingtonpost.co.uk/2012/08/22/tea-extract-cancer-diasappear_n_1821570.html

“Green Tea Ingredient Fights Cancer” http://articles.mercola.com/sites/articles/archive/2008/01/02/green-tea.aspx#!

“Green tea ‘can block cancer'” http://news.bbc.co.uk/2/hi/health/3125469.stm
 

“Green tea can cure mouth cancer & Fight bad breath” http://24by7news.com/news/health/green-tea-can-cure-mouth-cancer-fight-bad-breath/ 

tea 

 “Cheap tea ‘may pose health risk'” http://uk.news.yahoo.com/cheap-tea-may-pose-health-risk-160304199.html?.tsrc=lgwn#w5HMWLW 

 

“Cheaper supermarket teas could cause fluoride related illnesses”   http://medicalxpress.com/news/2013-07-cheaper-supermarket-teas-fluoride-illnesses.html

“Cannabis tea revisited: a systematic evaluation of the cannabinoid composition of cannabis tea.” http://www.ncbi.nlm.nih.gov/pubmed/17604926

Prevention of carcinogenesis by tea polyphenols – Science

Green Tea
 

“Prevention of carcinogenesis by tea polyphenols… Tea has been considered a medicine and healthful beverage for ages. The beneficial effects of tea are thought to be due to its polyphenolic components….Tea is one of the few chemopreventive agents known to have protective effects at different stages of the carcinogenic process….” http://www.ncbi.nlm.nih.gov/pubmed/11768768

“Tea and tea polyphenols in cancer prevention… The inhibitory action of tea (Camellia sinensis) and tea components against cancer formation has been demonstrated in different animal models involving different organ sites in many laboratories… tea polyphenols affect signal transduction pathways, inhibit cell proliferation and induce apoptosis,”  http://www.ncbi.nlm.nih.gov/pubmed/10721932

“Polyphenols as cancer chemopreventive agents.” http://www.ncbi.nlm.nih.gov/pubmed/8538195

“Mechanisms of inhibition of carcinogenesis by tea.” http://www.ncbi.nlm.nih.gov/pubmed/11237203

“Antioxidative and anti-carcinogenic activities of tea polyphenols” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820244/ 

“Cancer chemopreventive activity and bioavailability of tea and tea polyphenols… Consumption of tea has been associated with many health benefits including the prevention of cancer.” http://www.ncbi.nlm.nih.gov/pubmed/12628518

“Chemopreventive and therapeutic potential of tea polyphenols in hepatocellular cancer.” http://www.ncbi.nlm.nih.gov/pubmed/23530632

“Cancer chemoprevention by tea polyphenols… Tea is one of the most widely consumed beverages, second only to water… inhibitory effects of tea against carcinogenesis… tea polyphenols function as cancer chemopreventive agents” http://www.ncbi.nlm.nih.gov/pubmed/10786933

“Tea antioxidants in cancer chemoprevention… properties of tea polyphenols make them effective chemopreventive agents against the initiation, promotion, and progression stages of multistage carcinogenesis.”  http://www.ncbi.nlm.nih.gov/pubmed/9591194 

“Chemopreventive potential of flavonoids in oral squamous cell carcinoma in human studies… These flavonoids, abundant in green tea and black raspberries, respectively, represent promising chemopreventive agents in human oral cancer.”  http://www.ncbi.nlm.nih.gov/pubmed/23857227 

Cancer prevention by tea: Evidence from laboratory studies… The cancer preventive activities of tea (Camellia sinensis Theaceae) have been studied extensively. Inhibition of tumorigenesis by green tea extracts and tea polyphenols has been demonstrated in different animal models, including those for cancers of the skin, lung, oral cavity, esophagus, stomach, small intestine, colon, bladder, liver, pancreas, prostate, and mammary glands.” http://www.ncbi.nlm.nih.gov/pubmed/21397027

“Comparative antimutagenic and anticancer activity of three fractions of black tea polyphenols thearubigins.” http://www.ncbi.nlm.nih.gov/pubmed/21919645

“Hepatoprotective and antioxidant activity of standardized herbal extracts.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3371432/

“[Anti-inflammatory effects of tea-flavonoids]… Tea flavonoids belong to the large group of polyphenols and display antioxidative, anti-inflammatory and anti-neoplastic activities… Dietary supplementation with specific tea-flavonoids… could ultimately lead to inhibition of carcinogenesis.” http://www.ncbi.nlm.nih.gov/pubmed/23233307

“Tea and health: Studies in humans.” http://www.ncbi.nlm.nih.gov/pubmed/23448443

“Prevention of chronic diseases by tea: possible mechanisms and human relevance.”  http://www.ncbi.nlm.nih.gov/pubmed/23642203

“Active extracts of black tea (Camellia Sinensis) induce apoptosis of PC-3 prostate cancer cells via mitochondrial dysfunction… Many studies have shown that black tea reduces the risk of several types of cancer… these findings suggest that black tea could act as an effective anti-proliferative agent…” http://www.ncbi.nlm.nih.gov/pubmed/23715786

“Epicatechins Purified from Green Tea (Camellia sinensis) Differentially Suppress Growth of Gender-Dependent Human Cancer Cell Lines.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475929/

“Effects of green tea, black tea, and coffee consumption on the risk of esophageal cancer: a systematic review and meta-analysis of observational studies.” http://www.ncbi.nlm.nih.gov/pubmed/23368908

“Protective effect of green tea on the risks of chronic gastritis and stomach cancer.” http://www.ncbi.nlm.nih.gov/pubmed/11304697

“The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946098/

“Growth inhibition of Walker carcinosarcoma 256 with alcoholic extract of green tea leaves (Camellia sinensis).” http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502012000900008&lng=en&nrm=iso&tlng=en

“Health-promoting effects of green tea… anti-cancer, anti-obesity, anti-atherosclerotic, anti-diabetic, anti-bacterial, and anti-viral…” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365247/

“Meta-analysis of Green Tea Drinking and the Prevalence of Gynecological Tumors in Women… Our analysis indicates that drinking green tea can significantly decrease the risk of ovarian cancer.” http://www.ncbi.nlm.nih.gov/pubmed/23858521

“Polyphenols in brewed green tea inhibit prostate tumor xenograft growth by localizing to the tumor and decreasing oxidative stress and angiogenesis… administration of green tea (GT) extracts in drinking water can inhibit tumor growth…” http://www.ncbi.nlm.nih.gov/pubmed/22405694

“Medicinal benefits of green tea: Part I. Review of noncancer health benefits.” http://www.ncbi.nlm.nih.gov/pubmed/15992239

“Medicinal benefits of green tea: part II. review of anticancer properties.” http://www.ncbi.nlm.nih.gov/pubmed/16131288

“Green tea (Camellia sinensis) extract and its possible role in the prevention of cancer.” http://www.ncbi.nlm.nih.gov/pubmed/10559550

“Green tea (Camellia sinensis) and cancer prevention: a systematic review of randomized trials and epidemiological studies” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577676/

“Green tea (Camellia sinensis) for the prevention of cancer.” http://www.ncbi.nlm.nih.gov/pubmed/19588362

“Green tea prevents non-melanoma skin cancer by enhancing DNA repair.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077767/

“Green tea inhibits cycolooxygenase-2 in non-small cell lung cancer cells through the induction of Annexin-1.” http://www.ncbi.nlm.nih.gov/pubmed/23036202

“Green tea for ovarian cancer prevention and treatment: a systematic review of the in vitro, in vivo and epidemiological studies.” http://www.ncbi.nlm.nih.gov/pubmed/22564714

“Green tea: an effective synergist with anticancer drugs for tertiary cancer prevention.” http://www.ncbi.nlm.nih.gov/pubmed/22626556

“Medicinal Cannabis Does Not Influence the Clinical Pharmacokinetics of Irinotecan and Docetaxel… Coadministration of medicinal cannabis, as herbal tea, in cancer patients treated with irinotecan or docetaxel does not significantly influence the plasma pharmacokinetics of these drugs… medicinal cannabis can be administered concomitantly with both anticancer agents without dose adjustments.”  http://theoncologist.alphamedpress.org/content/12/3/291.long