Tag Archives: cannabis

Low Doses of THC (Cannabis) Can Halt Brain Damage, Study Suggests – ScienceDaily

Posted on by

“The use of THC can prevent long-term cognitive damage that results from brain injury, the researchers conclude.

Preventative and long-term use

According to Prof. Sarne, there are several practical benefits to this treatment plan. Due to the long therapeutic time window, this treatment can be used not only to treat injury after the fact, but also to prevent injury that might occur in the future. For example, cardiopulmonary heart-lung machines used in open heart surgery carry the risk of interrupting the blood supply to the brain, and the drug can be delivered beforehand as a preventive measure. In addition, the low dosage makes it safe for regular use in patients at constant risk of brain injury, such as epileptics or people at a high risk of heart attack.

Prof. Sarne is now working in collaboration with Prof. Edith Hochhauser of the Rabin Medical Center to test the ability of low doses of THC to prevent damage to the heart. Preliminary results indicate that they will find the same protective phenomenon in relation to cardiac ischemia, in which the heart muscle receives insufficient blood flow.”

More: http://www.sciencedaily.com/releases/2013/05/130530132531.htm

THC Can Prevent Brain Damage – Study

Posted on by

“Marijuana became popular as a recreational drug and as its legalization movement became more popular, studies were conducted on its therapeutic properties. Medical cannabis is often used by sufferers of chronic ailments, including cancer and post-traumatic stress disorder, to combat pain, insomnia, lack of appetite, and other symptoms. But self-reported milder symptoms often claim that only marijuana helps…

Prof. Yosef Sarne in the Department of Physiology and Pharmacology at Tel Aviv University says that the drug can go beyond symptoms – it also has neuroprotective qualities. He has found that extremely low doses of THC — the psychoactive component of marijuana — protects the brain from long-term cognitive damage in the wake of injury from hypoxia (lack of oxygen), seizures, or toxic drugs…

The use of THC can prevent long-term cognitive damage that results from brain injury, the researchers conclude…

According to Sarne, there are several practical benefits to this treatment plan. Due to the long therapeutic time window, this treatment can be used not only to treat injury after the fact, but also to prevent injury that might occur in the future. For example, cardiopulmonary heart-lung machines used in open heart surgery carry the risk of interrupting the blood supply to the brain, and the drug can be delivered beforehand as a preventive measure. In addition, the low dosage makes it safe for regular use in patients at constant risk of brain injury, such as epileptics or people at a high risk of heart attack.

Sarne is now working with Prof. Edith Hochhauser of the Rabin Medical Center to test the ability of low doses of THC to prevent damage to the heart. Preliminary results indicate that they will find the same protective phenomenon in relation to cardiac ischemia, in which the heart muscle receives insufficient blood flow.”

More: http://www.science20.com/news_articles/thc_can_prevent_brain_damage_study-113512

Extremely low doses of THC protect the brain from long-term cognitive damage

Posted on by

“Conditioning the brain. Extremely low doses of marijuana’s psychoactive component protect brain before and after injury, says Tel Aviv University researcher.

While performing experiments on the biology of cannabis, Prof. Sarne and his fellow researchers discovered that low doses of the drug had a big impact on cell signalling, preventing cell death and promoting growth factors. This finding led to a series of experiments designed to test the neuroprotective ability of THC in response to various brain injuries.

In the lab, the researchers injected mice with a single low dose of THC either before or after exposing them to brain trauma. A control group of mice sustained brain injury but did not receive the THC treatment. When the mice were examined 3 to 7 weeks after initial injury, recipients of the THC treatment performed better in behavioral tests measuring learning and memory. Additionally, biochemical studies showed heightened amounts of neuroprotective chemicals in the treatment group compared to the control group.”

More: http://www.news-medical.net/news/20130531/Extremely-low-doses-of-THC-protect-the-brain-from-long-term-cognitive-damage.aspx

Cognitive damage halted by THC in marijuana, Israeli reseachers discover

Posted on by
“Marijuana is a well-known recreational drug with much of its notoriety and controversy arise from its use as a psychoactive drug, however, scientific research into the therapeutic value has increased within the last 10 years revealing cannabis’ remarkable capability to combat disease.”
 
Medical Marijuana  
 
 

Marijuana component can halt brain damage

Posted on by

“Extremely low doses of THC, the psychoactive component of marijuana, protects the brain from long-term cognitive damage in case of injury from hypoxia (lack of oxygen), seizures, or toxic drugs, a new study has claimed.

Medical cannabis is often used by sufferers of chronic ailments, including cancer and post-traumatic stress disorder, to combat pain, insomnia, lack of appetite, and other symptoms.

Now, Professor Yosef Sarne of Tel Aviv University’s Adelson Center for the Biology of Addictive Diseases at the Sackler Faculty of Medicine in US found the drug has neuroprotective qualities as well.

Previous studies focused on injecting high doses of THC within a very short time frame approximately 30 minutes before or after injury.

Sarne’s current research, published in the journals Behavioural Brain Research and Experimental Brain Research, demonstrates that even extremely low doses of THC around 1,000 to 10,000 times less than that in a conventional marijuana cigarette administered over a wide window of 1 to 7 days before or 1 to 3 days after injury can jump start biochemical processes which protect brain cells and preserve cognitive function over time.

This treatment, especially in light of the long time frame for administration and the low dosage, could be applicable to many cases of brain injury and be safer over time, Sarne said.

While performing experiments on the biology of cannabis, researchers found that low doses of the drug had a big impact on cell signalling, preventing cell death and promoting growth factors.

This finding led to a series of experiments designed to test the neuroprotective ability of THC in response to various brain injuries.

In the lab, the researchers injected mice with a single low dose of THC either before or after exposing them to brain trauma. A control group of mice sustained brain injury but did not receive the THC treatment.”

http://www.indianexpress.com/news/marijuana-component-can-halt-brain-damage/1123274/

Low doses of marijuana component can protect brain against injury

Posted on by

Low doses of marijuana component can protect brain against injury

 

 

 

 

 

 

“Though marijuana is a well-known recreational drug, extensive scientific research has been conducted on the therapeutic properties of marijuana in the last decade. Medical cannabis is often used by sufferers of chronic ailments, including cancer and post-traumatic stress disorder, to combat pain, insomnia, lack of appetite, and other symptoms.

Now Prof. Yosef Sarne of Tel Aviv University’s Adelson Center for the Biology of Addictive Diseases at the Sackler Faculty of Medicine says that the drug has neuroprotective qualities as well. He has found that extremely low doses of THC—the psychoactive component of marijuana—protects the brain from long-term cognitive damage in the wake of injury from hypoxia (lack of oxygen), seizures, or toxic drugs. Brain damage can have consequences ranging from mild cognitive deficits to severe neurological damage.

Previous studies focused on injecting high doses of THC within a very short time frame—approximately 30 minutes—before or after injury. Prof. Sarne’s current research, published in the journals Behavioural Brain Research and Experimental Brain Research, demonstrates that even extremely low doses of THC—around 1,000 to 10,000 times less than that in a conventional marijuana cigarette—administered over a wide window of 1 to 7 days before or 1 to 3 days after injury can jumpstart biochemical processes which protect brain cells and preserve cognitive function over time.

This treatment, especially in light of the long time frame for administration and the low dosage, could be applicable to many cases of brain injury and be safer over time…”

More: http://medicalxpress.com/news/2013-05-doses-marijuana-component-brain-injury.html

Marijuana’s THC Can Halt Brain Damage

Posted on by

Cannabis. Image: Hupu2, Wikimedia

“Though marijuana is a well-known recreational drug, extensive scientific research has been conducted on the therapeutic properties of marijuana in the last decade. Medical cannabis is often used by sufferers of chronic ailments, including cancer and post-traumatic stress disorder, to combat pain, insomnia, lack of appetite and other symptoms.

Now Prof. Yosef Sarne of Tel Aviv Univ.’s Adelson Center for the Biology of Addictive Diseases at the Sackler Faculty of Medicine says that the drug has neuroprotective qualities as well. He has found that extremely low doses of THC — the psychoactive component of marijuana — protects the brain from long-term cognitive damage in the wake of injury from hypoxia (lack of oxygen), seizures or toxic drugs. Brain damage can have consequences ranging from mild cognitive deficits to severe neurological damage.

Previous studies focused on injecting high doses of THC within a very short time frame — approximately 30 minutes — before or after injury. Sarne’s current research, published in the journals Behavioural Brain Research and Experimental Brain Research, demonstrates that even extremely low doses of THC — around 1,000 to 10,000 times less than that in a conventional marijuana cigarette — administered over a wide window of one to seven days before or one to three days after injury can jumpstart biochemical processes which protect brain cells and preserve cognitive function over time.

This treatment, especially in light of the long time frame for administration and the low dosage, could be applicable to many cases of brain injury and be safer over time, Sarne says.”

More: http://www.laboratoryequipment.com/news/2013/05/marijuanas-thc-can-halt-brain-damage

Is marijuana bad for you?

Posted on by

“Hasn’t pot always been considered harmful?
Not at all. Marijuana, the dried form of the plant Cannabis sativa, was used as an herbal remedy for centuries in China, the Middle East, and Asia. William O’Shaughnessy, a physician for the East India Tea Company, brought it west in the 1830s as a treatment for rheumatism, tetanus, and rabies. It was commonly prescribed as a pain reliever in the U.S. until the 1930s, when its growing popularity caused such concern that the newly founded Federal Bureau of Narcotics reclassified it as a narcotic. The bureau soon launched a decidedly unscientific campaign claiming that marijuana use provoked insanity, homicidal tendencies, and uncontrollable lust. The marijuana user, the bureau asserted, “becomes a fiend with savage or ‘caveman’ tendencies. His sex desires are aroused, and some of the most horrible crimes result.””

Adolescents who smoked marijuana at least four times a week, lost an average of 8 IQ points between the ages of 13 and 38, according to a study from New Zealand.

“Was there any evidence for such claims?
None; in fact, the American Medical Association argued against marijuana prohibition in the 1930s, citing its therapeutic potential. But the bureau made its case that marijuana was “dangerous for the mind and the body,” and the federal government outlawed its use in 1937. It wasn’t until the 1970s that a campaign began to restore marijuana’s therapeutic reputation, and in 1996 California became the first state to legalize cannabis for medicinal purposes. Psychiatrist Tod Mikuriya, a founding father in the medical marijuana movement, claimed that cannabis has none of the adverse side effects of opiates. “In fact,” he said, “it really enhances both quality of life and rehabilitation.””

More: http://theweek.com/article/index/236671/is-marijuana-bad-for-you

Marijuana Vaporizer Provides Same Level Of THC, Fewer Toxins, Study Shows

Posted on by

“A smokeless cannabis-vaporizing device delivers the same level of active therapeutic chemical and produces the same biological effect as smoking cannabis…

…smoked cannabis can alleviate the chronic pain caused by HIV-related neuropathy, but a concern was expressed that smoking cannabis was not safe. This study demonstrates an alternative method that gives patients the same effects and allows controlled dosing but without inhalation of the toxic products in smoke,” said study lead author Donald I. Abrams, MD, UCSF professor of clinical medicine.

…pills tend to provide patients with more THC than they need for optimal therapeutic effect and increase side effects.

Patients rated the “high” they experienced from both smoking and vaporization and there was no difference between the two methods by patient self-report of the effect, according to study findings. In addition, patients were asked which method they preferred.

“By a significant majority, patients preferred vaporization to smoking, choosing the route of delivery with the fewest side effects and greatest efficiency,” said Benowitz.”

Read more: http://www.sciencedaily.com/releases/2007/05/070515151145.htm

Bogarting that joint might decrease oral hpv among cannabis users

Posted on by

Logo of curroncol

“The development of oral cancer is not a result of smoking cannabis per se; rather, it is hypothesized to be a result of contracting hpv through various forms of sharing and passing joints and other smoking apparatuses. Therefore, it is hypothesized that bogarting (and not passing) joints might decrease oral hpv among cannabis smokers.

It certainly may not be the cannabis smoke that causes oral cancers in heavy cannabis users. Most people who have ever smoked cannabis have most likely done so by sharing a rolled cigarette or pipe in a group setting. The sharing and passing of these smoking devices from an oral hpv-infected individual to an uninfected individual could easily provide a route of transmission for the virus between users. Frequency and setting should therefore be considered two major factors that might contribute to the likelihood of acquiring oral hpv.

Thus, the relationship between cannabis and various cancer types might not be from cannabis use itself, but rather from contracting high-risk types of oral hpv that lead to cancer in later life.”

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794675/