Category Archives: News Stories

Chemicals in Marijuana Could Help Treat MS

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TAU researchers have found that chemicals in marijuana could help treat multiple sclerosis. (Source: AFTAU)

“TAU researchers have found that chemicals in marijuana could help treat multiple sclerosis.

Multiple sclerosis is an inflammatory disease in which the immune system attacks the nervous system. The result can be a wide range of debilitating motor, physical, and mental problems. No one knows why people get the disease or how to treat it. 

In a new study published in the Journal of Neuroimmune Pharmacology, Drs. Ewa Kozela, Ana Juknat, Neta Rimmerman and Zvi Vogel of Tel Aviv University’s Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases and Sackler Faculty of Medicine demonstrate that some chemical compounds found in marijuana can help treat MS-like diseases in mice by preventing inflammation in the brain and spinal cord…”
 
 

“Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype” http://link.springer.com/article/10.1007/s11481-013-9493-1 

Sending Multiple Sclerosis Up in Smoke

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The illustration is of the cannabis sativa plant.

 “TAU researchers find chemicals in marijuana could help treat MS.

Multiple sclerosis is an inflammatory disease in which the immune system attacks the nervous system. The result can be a wide range of debilitating motor, physical, and mental problems. No one knows why people get the disease or how to treat it.

In a new study published in the Journal of Neuroimmune Pharmacology, Drs. Ewa Kozela, Ana Juknat, Neta Rimmerman and Zvi Vogel of Tel Aviv University’s Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases and Sackler Faculty of Medicine demonstrate that some chemical compounds found in marijuana can help treat MS-like diseases in mice by preventing inflammation in the brain and spinal cord.

“Inflammation is part of the body’s natural immune response, but in cases like MS it gets out of hand,” says Kozela. “Our study looks at how compounds isolated from marijuana can be used to regulate inflammation to protect the nervous system and its functions.” Researchers from the Weizmann Institute of Science co-authored the study…”

More: http://neurosciencenews.com/neurology-thc-cbd-multiple-sclerosis-482/

 “Sending Multiple Sclerosis Up in Smoke” http://www.sciencedaily.com/releases/2013/10/131007132253.htm

“Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype” http://link.springer.com/article/10.1007/s11481-013-9493-1

Researchers find chemicals in marijuana could help treat MS

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Researchers find chemicals in marijuana could help treat MS

“In a new study published in the Journal of Neuroimmune Pharmacology, Drs. Ewa Kozela, Ana Juknat, Neta Rimmerman and Zvi Vogel of Tel Aviv University’s Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases and Sackler Faculty of Medicine demonstrate that some chemical compounds found in marijuana can help treat MS-like diseases in mice by preventing inflammation in the brain and spinal cord.

“Inflammation is part of the body’s natural immune response, but in cases like MS it gets out of hand,” says Kozela. “Our study looks at how compounds isolated from marijuana can be used to regulate inflammation to protect the nervous system and its functions.” Researchers from the Weizmann Institute of Science co-authored the study.”

More: http://medicalxpress.com/news/2013-10-chemicals-marijuana-ms.html

“Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype” http://link.springer.com/article/10.1007/s11481-013-9493-1

Tel Aviv University researchers find chemicals in marijuana could help treat MS

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“Multiple sclerosis is an inflammatory disease in which the immune system attacks the nervous system. The result can be a wide range of debilitating motor, physical, and mental problems. No one knows why people get the disease or how to treat it.

In a new study published in the Journal of Neuroimmune Pharmacology, Drs. Ewa Kozela, Ana Juknat, Neta Rimmerman and Zvi Vogel of Tel Aviv University’s Dr. Miriam and Sheldon G. Adelson Center for the Biology of Addictive Diseases and Sackler Faculty of Medicine demonstrate that some chemical compounds found in marijuana can help treat MS-like diseases in mice by preventing inflammation in the brain and spinal cord…”

More: http://www.news-medical.net/news/20131008/Tel-Aviv-University-researchers-find-chemicals-in-marijuana-could-help-treat-MS.aspx

“Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype” http://link.springer.com/article/10.1007/s11481-013-9493-1

Want Leukemia “awareness”? Please, BE AWARE:

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“Increase in rare childhood cancers linked to air pollution exposure” http://in.news.yahoo.com/increase-rare-childhood-cancers-linked-air-pollution-exposure-063414538.html
“Air Pollution and Childhood Cancer. A new study finds a link between air pollution exposure during pregnancy and childhood leukemia.”
http://health.yahoo.net/videos/healthday/air-pollution-and-childhood-cancer
“UCLA researchers find potential link between auto pollution, some childhood cancers” http://newsroom.ucla.edu/portal/ucla/ucla-researchers-link-auto-pollution-244911.aspx
“UCLA Researchers Find Potential Link Between Air Pollution And Childhood Cancer” http://losangeles.cbslocal.com/2013/04/09/ucla-researchers-find-potential-link-between-air-pollution-and-childhood-cancer/
“Leukemia, Other Pediatric Cancers Linked to Air Pollution”
http://www.empr.com/leukemia-other-pediatric-cancers-linked-to-air-pollution/article/288041/

“Air Pollution From Traffic Linked With Childhood Cancer” http://www.huffingtonpost.com/2013/04/09/air-pollution-traffic-childhood-cancer_n_3039048.html

“Leukemia, Other Pediatric Cancers Linked to Air Pollution” http://www.empr.com/leukemia-other-pediatric-cancers-linked-to-air-pollution/article/288041/

“NIH study finds childhood CT scans linked to leukemia and brain cancer later in life” http://nih.gov/news/health/jun2012/nci-07.htm
“NIH study finds childhood CT scans linked to leukemia and brain cancer later in life” http://www.cancer.gov/newscenter/newsfromnci/2012/CTpediatricLancet
“Childhood CT Scans Linked to Leukemia and Brain Cancer Later in Life” http://news.cancerconnect.com/childhood-ct-scans-linked-to-leukemia-and-brain-cancer-later-in-life/
“Childhood CT Scans Linked to Later Leukemia, Brain Cancer” http://www.medscape.com/viewarticle/765223

“Multiple CT scans in kids linked to later cancer risk” http://www.nbcnews.com/health/multiple-ct-scans-kids-linked-later-cancer-risk-6C10272110

“Link Between X-Rays And Increased Childhood Leukemia Risk”
http://www.medicalnewstoday.com/articles/203521.php
“X-rays can cause childhood leukemia”
http://www.naturalnews.com/029961_X-rays_leukemia.html

“X-Rays Linked to Increased Childhood Leukemia Risk” http://www.sciencedaily.com/releases/2010/10/101004101324.htm

“Survival at a Cost: Common Cancer Treatment Carries Huge Risks” http://abcnews.go.com/Health/radiation-therapy-linked-development-secondary-cancers-heart-disease/story?id=15864706

“Treatments linked to the development of second cancers”
http://www.cancer.org/cancer/cancercauses/othercarcinogens/medicaltreatments/secondcancerscausedbycancertreatment/second-cancers-caused-by-cancer-treatment-treatments-linked-to-second-cancers

“Decades Later, Chernobyl Accident Yields Clues to Leukemia Risk”
http://www.cancer.gov/ncicancerbulletin/111312/page5
“Exposure to low-level radiation can cause leukemia, U.S.-Ukraine study of Chernobyl cleanup workers finds” http://www.japantimes.co.jp/news/2012/11/09/national/exposure-to-low-level-radiation-can-cause-leukemia-u-s-ukraine-study-of-chernobyl-cleanup-workers-finds/
“Risk for Acute Myeloid Leukemia Linked to Chemotherapy”
http://www.medscape.com/viewarticle/779653
“Cancer Chemotherapy Tied to Slight Rise in Risk for Leukemia” http://www.drugs.com/news/cancer-chemotherapy-tied-slight-rise-risk-leukemia-43125.html
“Chemo Raises Leukemia Risk Slightly in Older Women”
http://www.breastcancer.org/research-news/20070924b
“Woops! Study Accidentally Finds Chemotherapy Makes Cancer Far Worse” http://naturalsociety.com/chemotherapy-makes-cancer-far-worse/
“Shock study: Chemotherapy can backfire, make cancer worse by triggering tumor growth” http://www.nydailynews.com/life-style/health/shock-study-chemotherapy-backfire-cancer-worse-triggering-tumor-growth-article-1.1129897
“Immunity Boosters Linked to Leukemia”
http://www.cbsnews.com/2100-500368_162-2441362.html
“Drugs That Boost Immunity During Cancer Chemo May Carry Leukemia Risk” http://www.webmd.com/breast-cancer/news/20070206/immunity-boosters-linked-leukemia
“Study: GMOs linked to leukemia and anemia”
http://www.digitaljournal.com/article/350126
“Agent Orange Linked to Childhood Cancer”
http://abcnews.go.com/Health/story?id=117503&page=1
“Agent Orange, Leukemia Linked”
http://www.cbsnews.com/2100-204_162-537775.html
“Insecticides: Potential Leukemia Risk. Study Examines Possible Link Between Head Lice Shampoo and Childhood Leukemia”
http://www.webmd.com/cancer/news/20060118/insecticides-potential-leukemia-risk
“Bug Spray Use Linked to Childhood Leukemia” http://www.medpagetoday.com/HematologyOncology/Leukemia/2503
“Fertility drugs linked to leukaemia”
http://news.uk.msn.com/uk/fertility-drugs-linked-to-leukaemia
“High blood sugar ups mortality in leukemia patients”
http://www.reuters.com/article/2007/08/30/us-high-blood-sugar-idUSKUA07460320070830
“NutraSweet Linked to Leukemia and Lymphoma”
http://www.naturalnews.com/026656_aspartame_leukemia_formaldehyde.html
“Sucralose Causes Cancer Concern” http://www.medicalnewstoday.com/articles/244603.php
“Splenda May Not Be So Splendid After All” http://news.yahoo.com/splenda-may-not-splendid-194239789.html
“Sweetener ‘linked’ to leukaemias” http://news.bbc.co.uk/2/hi/health/4683371.stm
“Diet Soft Drinks, Sodas can cause leukemia and lymphoma” http://www.agoracosmopolitan.com/news/headline_news/2012/11/02/4720.html
“Aspartame is linked to leukemia and lymphoma in new landmark study on humans” http://www.naturalnews.com/037772_aspartame_leukemia_lymphoma.html
“Doctors find link between obesity, leukemia” http://abclocal.go.com/kabc/story?id=7670509
“Obesity and Leukemia: Fat May Offer Sanctuary to Cancer Cells”
http://www.usnews.com/science/articles/2009/09/23/linking-obesity-with-leukemia-relapses
“Tea Ingredient Fights Leukemia. Lab Study: Green, Black, and Oolong Tea Boosts Immune Responses”
http://www.webmd.com/cancer/news/20050404/tea-ingredient-fights-leukemia

“Higher lymphoma risk for those living close to benzene-releasing sites, Georgia study finds” http://medcitynews.com/2013/07/higher-lymphoma-risk-for-those-living-close-to-benzene-releasing-sites-georgia-study-finds/

“Home distance from benzene sites linked to lymphoma risk”
http://www.nlm.nih.gov/medlineplus/news/fullstory_139158.html

“Benzene Exposure Linked to Increased Rate of NHL”
http://www.medscape.com/viewarticle/808573
“Samsung Chip Factory Causes Cancer, South Korea Government Finds” http://www.huffingtonpost.com/2012/12/14/samsung-chip-factory-cancer_n_2298294.html
“China’s Cancer-Causing Factories”
http://www.cbsnews.com/8301-18563_162-5237961.html
“Formaldehyde and Leukemia: Epidemiology, Potential Mechanisms and Implications for Risk Assessment” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839060/
“Formaldehyde Exposure among Industrial Workers Is Associated with Increased Risk of Cancers of the Blood and Lymphatic System” http://www.cancer.gov/newscenter/newsfromnci/2009/formaldehyde
“Hexavalent Chromium, Cancer-Causing Toxin, Common in Tap Water: What to Do” http://www.cbsnews.com/8301-504763_162-20026157-10391704.html
“Chromium in Drinking Water Causes Cancer”
http://www.scientificamerican.com/article.cfm?id=chromium-water-cancer
“Lack of vitamin D in patients with leukemia “ups death risk””
http://www.dailyindia.com/show/406851.php
“The Vitamin D and Cancer Connection: Research Shows the Link”
http://news.cancerconnect.com/the-vitamin-d-and-cancer-connection-research-shows-the-link/

“Insufficient Vitamin D Levels in Chronic Lymphocytic Leukemia Patients Linked to Cancer Progression and Death”
http://www.sciencedaily.com/releases/2010/11/101104094038.htm

“Mayo Clinic Finds Insufficient Vitamin D Levels in CLL Patients Linked to Cancer Progression and Death”
http://www.mayoclinic.org/news2010-rst/6033.html

Be aware:  http://www.thctotalhealthcare.com/category/leukemia/

 ferrando stock child

Cannabidiol (CBD) Shown To Kill Breast Cancer Cells

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 “Cannabidiol (CBD) has been on the receiving end of a lot of attention from the scientific community for several decades now. However, it is only now that we are really starting to begin to get a grasp on how wonderful this cannabinoid truly is.

 

A study from 2011 states that cannabidiol is considered an antineoplastic agent on the basis of its in vitro and in vivo activity against tumor cells. However, the exact molecular mechanism through which CBD works in this capacity is yet to be understood. The study, titled “Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy,” focuses on how CBD can kill breast cancer cells. Breast cancer is the second leading cause of cancer-related death in women in the United States.

What the scientists found was that CBD influences apoptosis by interacting with a key protein, called beclin-1, found within the cancerous cell. Beclin-1 is also known to play a key role in autophagy, or cellular self-degradation of non-vital components, which may lead to programmed cell death. This causes a distortion of the electrical signals between the outer mitochondrial membrane and the rest of the cell, disrupting the transfer to the cell interior of certain molecules that are necessary for metabolism. What this means is that the cell cannot transfer energy, and the cell starves to death, and in doing so activates the self-destruction process of apoptosis.

The study concludes by stating, “In summary, we showed that CBD, a plant-derived cannabinoid, preferentially kills breast cancer cells by inducing ER stress, inhibiting mTOR signaling, enhancing ROS generation, and mediating a complex balance between autophagy and mitochondria-mediated apoptosis in MDA-MB-231 breast cancer cells. These findings support the continued exploration of CBD as an alternative agent for breast cancer treatment.””

http://cbdgum.networkofhemp.com/cannabidiol-cbd-shown-to-kill-breast-cancer-cells/

“Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy… In summary, we showed that CBD, a plant-derived cannabinoid, preferentially kills breast cancer cells…” http://mct.aacrjournals.org/content/10/7/1161.full

THC Gives Cancer Cells the Munchies Too

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“…THC and other cannabinoids are actively being investigated for various useful clinical purposes, including the treatment of cancer through the inhibition of tumor growth.

A new study by Salazar et al. in The Journal of Clinical Investigation demonstrates that THC causes tumor cells to begin to degrade themselves from the inside (a process called autophagy, i.e. “self-eating”). Although autophagy has been shown to promote cell survival in some cases and cell death in others, the authors show that in this case it causes cancer cells to undergo programmed cell death (apoptosis). Thus, THC activates a series of events within cancer cells, inhibiting tumor growth.”

More: http://scienceblogs.com/scientificactivist/2009/04/02/thc-gives-cancer-cells-the-mun/

“Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673842/

No Association Between Frequency of Marijuana Use and Health or Healthcare Utilization

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“Researchers from Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) have found frequency of marijuana use was not significantly associated with health services utilization or health status. These findings currently appear online in the Journal of General Internal Medicine.

As marijuana’s legal status changes across the US, its impact on health has become of great interest. Marijuana is the most commonly used illicit drug, yet its impact on health and healthcare utilization has not been studied extensively.

The researchers studied 589 adults who screened positive for drug use at a primary care visit. Those patients were asked about their drug use, their emergency room use and hospitalizations, and their overall health status. In addition, information about other medical diagnoses was obtained from their medical records. They found the vast majority of the study sample (84 percent) used marijuana, 25 percent used cocaine, 23 percent opioids and eight percent used other drugs; 58 percent reported using marijuana but no other drugs. They also found no differences between daily marijuana users and those using no marijuana in their use of the emergency room, in hospitalizations, medical diagnoses or their health status.

According to the researchers it is common for users of illicit drugs to use both marijuana and another drug; therefore, knowing the incremental effects of marijuana on health in that circumstance is important.

“Even though we could not compare marijuana users to those who used no drugs at all, our findings suggest that marijuana use has little measurable effect on self-reported health or healthcare utilization in adults using drugs identified in a primary care clinic,” said lead author Daniel Fuster, MD, a postdoctoral scholar from the Clinical Addiction Research and Education Unit at BMC and BUSM.”

http://www.sciencedaily.com/releases/2013/09/130923143638.htm

“No Detectable Association Between Frequency of Marijuana Use and Health or Healthcare Utilization Among Primary Care Patients Who Screen Positive for Drug Use.” http://www.ncbi.nlm.nih.gov/pubmed/24048656

 “Cannabis Consumption Has No Negative Effect on Health, According to New Study” https://thejointblog.com/cannabis-consumption-negative-effect-health-according-new-study/

Marijuana’s Active Ingredient Targets Deadly Brain Cancer – WebMD

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“If results of a recent rat study hold true in human trials, marijuana could be the treatment of choice for patients with malignant glioma — an especially aggressive and often fatal form of brain cancer.

 No, rats haven’t started smoking pot. But when researchers injected tumorous animals with cannabinoids — the drug’s active ingredient — about a third of them went into remission, and another third lived significantly longer than untreated rats.

The findings appear in the March issue of the journal Nature Medicine…

According to lead researcher Manuel Guzmán, PhD, his team’s previous studies showed that cannabinoids could stop growth and kill cancer cells but did not harm normal cells. The current work examined the action behind this effect and whether it would also work in living animals…

The researchers first caused tumors in the brains of 18 rats. They then injected the animals over the course of seven days with either a natural or artificial cannabinoid, or a placebo for comparison. Additional groups of healthy, tumor-free rats also received the various treatments…

All of the untreated animals with tumors died between days 12 and 18, but those treated with the cannabinoids lived much longer, and had significantly smaller tumors…

There were no negative side effects at all in the healthy animals receiving treatment.”

More:http://www.webmd.com/cancer/news/20000228/marijuanas-active-ingredient-targets-deadly-brain-cancer

“Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation” http://www.nature.com/nm/journal/v6/n3/abs/nm0300_313.html

Marijuana May Stall Brain Tumor Growth – WebMD

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“Active Ingredient in Marijuana Inhibits Cancer Growth in Early Study.
 
The active ingredient in marijuana may help fight brain tumors, a new study suggests.
 

Researchers say the cannabinoids found in marijuana may aid in brain tumor treatment by targeting the genes needed for the tumors to sprout blood vessels and grow.

Their study showed that cannabinoids inhibited genes needed for the production of vascular growth factor (VEGF) in laboratory mice with glioma brain tumors and two patients with late-stage glioblastoma multiforme, a form of brain cancer.

VEGF is a protein that stimulates blood vessels to grow. Tumors need an abundant blood supply because they generally grow rapidly. So when VEGF is blocked, tumors starve from lack of blood supply and nutrients.

Blocking of VEGF constitutes one of the most promising tumor-fighting approaches currently available, says researcher Manuel Guzman, professor of biochemistry and molecular biology, at the Complutense University in Madrid, Spain, in a news release.”

More:http://www.webmd.com/cancer/news/20040815/marijuana-stall-brain-tumor-growth 

“Cannabinoids Inhibit the Vascular Endothelial Growth Factor Pathway in Gliomas”:  http://cancerres.aacrjournals.org/content/64/16/5617.long

 

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