Marijuana May Fight Lung Tumors – CBSNews

“the active ingredient in marijuana may help combat lung cancer, new research suggests.

Moreover, other early research suggests the cannabis compound could help fight brain, prostate, and skin cancers as well, Preet says.

The finding builds on the recent discovery of the body’s own cannabinoid system, Preet says. Known as endocannabinoids, the natural cannabinoids stimulate appetite and control pain and inflammation.

THC seeks out, attaches to, and activates two specific endocannabinoids that are present in high amounts on lung cancer cells, Preet says. This revs up their natural anti-inflammatory properties. Inflammation can promote the growth and spread of cancer.

In the new study, the researchers first demonstrated that THC inhibited the growth and spread of cells from two different lung cancer cell lines and from patient lung tumors. Then, they injected THC into mice that had been implanted with human lung cancer cells. After three weeks, tumors shrank by about 50 percent, compared with tumors in untreated mice.”

 http://www.cbsnews.com/2100-500368_162-2696726.html

Cannabinoid receptor 1 is a potential drug target for treatment of translocation-positive rhabdomyosarcoma

“Because cannabinoid receptor agonists are capable of reducing proliferation and inducing apoptosis (cell death) in diverse cancer cells such as glioma, breast cancer, and melanoma, we evaluated whether CB1 is a potential drug target in rhabdomyosarcoma.

Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma in children…

 Our study shows that treatment with the cannabinoid receptor agonists HU210 (cloned THC from Hebrew University) and Delta(9)-tetrahydrocannabinol (THC from cannabis) lowers the viability of translocation-positive rhabdomyosarcoma cells through the induction of apoptosis…

These results support the notion that cannabinoid receptor agonists could represent a novel targeted approach for treatment of translocation-positive rhabdomyosarcoma.”

Full text: http://mct.aacrjournals.org/content/8/7/1838.long

Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis

“Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis…The endocannabinoid system and cannabimimetic compounds protect against effects of allergic inflammatory disorders in various species of mammals. Results of the present study contributed to knowledge of the endocannabinoid system and indicated this system may be a target for treatment of immune-mediated and inflammatory disorders such as allergic skin diseases in dogs.”

http://www.ncbi.nlm.nih.gov/pubmed/22738050

Cannabis and tobacco smoke are not equally carcinogenic

“Cannabis and tobacco smoke are not equally carcinogenic… Cannabis smoke contains cannabinoids whereas tobacco smoke contains nicotine (plus added carcinogens). Available scientific data, that examines the carcinogenic properties of inhaling smoke and its biological consequences, suggests reasons why tobacco smoke, but not cannabis smoke, may result in lung cancer… Furthermore, compounds found in cannabis have been shown to kill numerous cancer types including: lung cancer, breast and prostate, leukemia and lymphoma, glioma, skin cancer, and pheochromocytoma…”-

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1277837/?tool=pubmed

Cannabis Science Receives New Photos and Positive Feedback from Patient Three and an Oncologist about his Severe Squamous Cell Carcinoma

April 11, 2012

“COLORADO SPRING, Colo.–(BUSINESS WIRE)–Cannabis Science, Inc. (OTCBB: CBIS.OB) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is pleased to provide new photographs of the existing treatment for patient three who has a “worst case” of treatment resistant, Squamous Cell Carcinoma. Cannabis Science has received positive feedback from both the patient and his Oncologist. These photos show the progressive reduction of the tumor masses that has occurred within the months of treatment.”

http://www.cannabisscience.com/news-a-media/press-releases/285-cannabis-science-receives-new-photos-and-positive-feedback-from-patient-three-and-an-oncologist-about-his-severe-squamous-cell-carcinoma.html

Cannabis Science Reports Second Cancer Patient Receives Clean Biopsy Report Confirming the Biopsy is Free of Cancer Cells

“Cannabis Science, Inc. a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products is happy to report that patient #2, who had a Squamous cell carcinoma on her arm, has received her biopsy report. It confirms what was visually apparent from the photo-documentation on our website. Her biopsy was free of cancer cells and she will not need any surgical procedure. Nevertheless, the patient will continue with her self-administered topical application of extracts for a while longer to minimize any chance of any surviving cancer cells in areas beyond what was biopsied.”

More: http://www.tradershuddle.com/20120404422008/Press-Releases/cannabis-science-reports-second-cancer-patient-receives-clean-biopsy-report-confirming-the-biopsy-is-free-of-cancer-cells.html

Cannabis Science Reports Success For 4th Brand New Self-Administering Cancer Patient

February 2, 2012

“DENVER–(BUSINESS WIRE)– Cannabis Science, Inc. (OTCBB:CBIS.OB – News) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is pleased to introduce a 4th cancer patient with basal cell carcinoma (skin cancer) on his left nostril, who is self-administering a topical cannabis extract and having noticeable results.”

http://www.cannabisscience.com/news-a-media/press-releases/264-cannabis-science-reports-success-for-4th-brand-new-self-administering-cancer-patient.html

Cannabis Science Presents Newest Photographs From 3rd Cancer Patient That Show Cancer Tumors Dying and Areas That Are Now Pain Free

January 30, 2012

“DENVER–(BUSINESS WIRE)– Cannabis Science, Inc. (OTCBB:CBIS.OB) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is pleased to share new photographs from this cancer patient with severe squamous cell carcinoma. These pictures clearly show that this patient, with previously treatment-resistant tumors, continues to make obvious improvement. The tumors appear to be dying and then healing after treatment with cannabis-based extracts.”

http://www.cannabisscience.com/news-a-media/press-releases/262-cannabis-science-presents-newest-photographs-from-3rd-cancer-patient-that-show-cancer-tumors-dying-and-areas-that-are-now-pain-free.html

Cannabis Science Updates Second Medical Cannabis Cancer Patient Suffering from Squamous Cell Carcinoma Photo-documents Cannabis Extracts Killing Cancerous Tumor

“Cannabis Science, Inc. (OTCBB: CBIS) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is very pleased to announce that the second patient suffering from basal cell carcinoma (skin cancer) has self-administered cannabis extracts that appear to have eradicated the cancer.”

“Currently it appears that the aforementioned patient will be able to avoid any surgical procedures such as, standard surgical excision (Mohs Surgery), and other various types of treatment for skin cancer, like chemotherapy, radiation, and cryosurgery, by using the cannabis extracts…”

More: http://www.drugs.com/clinical_trials/cannabis-science-updates-second-medical-cannabis-cancer-patient-suffering-squamous-cell-carcinoma-12967.html

Cannabis Science Reports Apparent Success For 3rd Self-Medicated Cancer Patient

“Cannabis Science, Inc., a pioneering US biotech company developing pharmaceutical cannabis products, is happy to report an additional, apparently successful, self-medicated cannabis treatment for a cancer patient.

This case is very graphic in nature. One of the patient’s physicians said it was the worst case of squamous cell carcinoma cancer he had ever seen, while another refused to continue tending to the patient. 

While this patient’s self-administered treatment with cannabis extracts is still in progress, the results after just two weeks of treatment are dramatic. Some of the tumors have disappeared and others have significantly shrunk to a fraction of their original size. Simultaneously, the patient has had a significant decrease in pain, improved sleeping (the 1st full night of sleep in 3 years), as well as relief from the symptoms of multiple sclerosis that the patient also suffers from. This self-treatment is a work in progress.”

More: http://www.prnewswire.com/news-releases/cannabis-science-reports-apparent-success-for-3rd-self-medicated-cancer-patient-137111868.html