“Limited efficacy for current pharmacotherapy for PTSD indicates that improved pharmacological treatments are needed. Neurobiological research points to cannabinoids as possible therapeutic agents of interest. Moreover, observational reports indicate that there is growing popular interest in therapeutic use of cannabinoids for the alleviation of trauma symptoms. The aim of this review was to present an up-to-date look at current research on the possible therapeutic value of cannabinoids for PTSD. Experimental, preclinical, and clinical findings are discussed.
Highlights
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Neurobiological research indicates cannabis as possible pharmacological intervention for PTSD.
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CBD and THC + CBD modulate fear memory in rodents.
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Experimental data suggest CBD has acute anti-depressive and anxiolytic effects.
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Data suggest THC reduces nightmares and OSA, while THC + CBD could reduce insomnia.
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Randomized placebo-controlled human trials of cannabinoids for PTSD are underway.”
http://www.sciencedirect.com/science/article/pii/S2352250X16302342 https://www.researchgate.net/publication/311949481_Cannabinoids_as_therapeutic_for_PTSD
“Despite its controversial nature, the use of medical marijuana and cannabis-derived medicinal products grows more popular with each passing year. As of November 2016, over 40 states have passed legislation regarding the use of either medical marijuana or cannabidiol products. Many providers have started encountering patients experimenting with cannabis products for a wide range of conditions. While the debate continues regarding these agents for both medicinal and recreational use in the general population, special consideration needs to be made for pediatric use. This review will deliver the history of marijuana use and legislation in the United States in addition to the currently available medical literature to equip pediatric health care providers with resources to provide patients and their parents the best recommendation for safe and appropriate use of cannabis-containing compounds.”