Marijuana Saves Child With Seizures; Others Must Wait

“Parents of a 5-yr-old Colorado girl who suffered from severe seizures say medical marijuana has saved their child’s life.  Footage of the child before and after she was given cannabis was shown Sunday in a documentary, “Weed,” aired on CNN hosted by Sanjay Gupta, a neurosurgeon.
 

Buoyed by previously published reports and You-Tube videos of the child’s remarkable recovery, several New Jersey parents have been pushing for the opportunity to give cannabis to their seriously ill children.   They want Gov. Christie to sign a bill that would pave the way. 

Paige and Matt Figi said in the CNN interview that their daughter, Charlotte, had 300 seizures a week before she was administered drops of cannabis under her tongue a year ago.  She had been in a catatonic state, unable to eat, talk, or walk.  Now, after regularly using cannabis, she has only one seizure every seven days, the parents said.  Footage shows her talking, walking, laughing, riding a bicycle and also a horse. 

Forty-one other children had similar results, according to the documentary. 

Gupta traveled around the world, interviewing other seriously ill patients who got astonishing  results by using cannabis.  In Israel, some studies show the drug has helped sufferers of Crohn’s Disease, Post-Traumatic Stress Disorder and cancer. 

There also are detractors – doctors who say not enough research has been done, as interviewed by Gupta.  The American Academy of Pediatricians also oppose giving it to children.  

Meghan and Brian Wilson, the parents of two-year-old Vivian, who live in Scotch Plains, in North Jersey, have spent the last few months lobbying to get changes in New Jersey’s three-year-old marijuana law to make it easier for children to use cannabis.  It’s legal in the state for children to use it – in fact Vivian was issued a marijuana card in February because she too suffers from a severe type of epilepsy.  But cannabis is not allowed to be sold in edible form and requires three doctors to sign off on it before a child can obtain it. 

A bill that was overwhelming passed by the legislature is sitting on Gov. Christie’s desk.  He has said he is reluctant, but will consider it.  He has until Friday, Aug. 16, to decide.

It’s not known whether Christie watched the CNN documentary.” 

http://www.philly.com/philly/news/new_jersey/Marijuana-Saves-Child-With-Seizures-Others-Must-Wait–.html

Medical marijuana stopped girl’s seizures when nothing else would – msn

Photo of Charlotte Figi - Realm of Caring via Facebook

 

“Charlotte Figi had her first seizure in 2006, when she was 3 months old. Her parents, Matt and Paige Figi, had every test conducted, yet no cause could be found. Years passed, and the seizures continued. Charlotte took medications, but she stopped developing cognitively. She was finally diagnosed with a severe form of epilepsy, Dravet Syndrome. Matt discovered the case of a boy with Dravet who’d been helped by low-level THC medical marijuana. By that point, Charlotte couldn’t walk, talk or eat, and she was having up to 300 grand mal seizures a week.

Desperate to find a solution, Matt and Paige applied for a medical marijuana card, making Charlotte, then 5, the youngest applicant in Colorado. They gave her a small amount of cannabis oil. The seizures stopped. Now Charlotte takes the oil twice daily with food, has only a few seizures a week, and is walking, talking and riding her bike. “My thought now is why were we the ones that had to go out and find this cure? This natural cure?” says Matt. “How come [a doctor] didn’t make me aware of this?””

http://now.msn.com/charlotte-figi-colorado-girl-has-seizures-treated-by-medical-marijuana

“Meet the first 6-year-old medical marijuana user” http://fox2now.com/2013/08/12/meet-the-first-6-year-old-medical-marijuana-user/

Marijuana stops child’s severe seizures – CNN

“…Charlotte gets a dose of the cannabis oil twice a day in her food.

Gedde found three to four milligrams of oil per pound of the girl’s body weight stopped the seizures.

Today, Charlotte, 6, is thriving. Her seizures only happen two to three times per month, almost solely in her sleep. Not only is she walking, she can ride her bicycle. She feeds herself and is talking more and more each day.

“I literally see Charlotte’s brain making connections that haven’t been made in years,” Matt said. “My thought now is, why were we the ones that had to go out and find this cure? This natural cure? How come a doctor didn’t know about this? How come they didn’t make me aware of this?”

The marijuana strain Charlotte and now 41 other patients use to ease painful symptoms of diseases such as epilepsy and cancer has been named after the little girl who is getting her life back one day at a time.

It’s called Charlotte’s Web.”

More: http://www.cnn.com/2013/08/07/health/charlotte-child-medical-marijuana/index.html

Killing bacteria with cannabis

“Pharmacists and chemists have found another use for the multipurpose cannabis as a source of antibacterial chemicals for multidrug resistant bacteria.”

 

“All five cannabinoids (THC, CBD, CBG, CBC, and CBN) were potent against bacteria. Notably, they performed well against bacteria that were known to be multidrug resistant, like the strains of MRSA…

CBD and CBG have the most potential for consumer use because they are nonpsychotropic…”

More: http://arstechnica.com/science/2008/08/killing-bacteria-with-cannabis/

“Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.” http://www.ncbi.nlm.nih.gov/pubmed/18681481

Pot is good for you? Marijuana fights the superbugs

Fact: Cannabis Kills MRSA, Disrupts Prion Diseases

“Marijuana is a potent antibiotic that can kill methicillin-resistant Staphylococcus aureus and disrupt the progression of prion diseases such as Mad Cow disease and Creutzfeld-Jakob disease — just don’t expect the federal government to tell you any of this.”

A MRSA lesion

“Scientists from Italy and the United Kingdom reported in the August 2007 issue of the Journal of Natural Products that the main active ingredient in weed, THC, as well as four other pot molecules “showed potent antibacterial activity against six different strains of MRSA of clinical relevance.”

Pot also stops prions,  a type of protein that can cause neurodegenerative diseases that are invariably fatal. Once prions get into a brain they replicate rapidly and shred brain tissue “resulting in a ‘spongiform’ appearance on post-mortem histological examination of neural tissue.”

In 2007, American and French researchers reported that pot molecule cannabidiol “prevents prion accumulation and protects neurons against prion toxicity” in the Journal of Neuroscience.

Cannabidiol inhibited prion accumulation in mouse and sheep prion disease cell cultures and inhibited prion formation in the brain of infected mice given injections of CBD. “The authors conclude that CBD likely represents a new class of anti-prion drugs.””

More: http://www.eastbayexpress.com/LegalizationNation/archives/2013/07/29/fact-cannabis-kills-mrsa-disrupts-prion-diseases

“Antibacterial cannabinoids from Cannabis sativa: a structure-activity study.” http://www.ncbi.nlm.nih.gov/pubmed/18681481

“Nonpsychoactive Cannabidiol Prevents Prion Accumulation and Protects Neurons against Prion Toxicity” http://www.jneurosci.org/content/27/36/9537.full

Marijuana Kills MRSA and Inhibits Prions That Cause Neurodegenerative Disease; Still Recognized by Feds As a Dangerous Drug

“Research indicates that marijuana could effectively fight off MRSA, as well as prions — the proteins that cause mad cow disease and Creutzfeld-Jakob disease.”

(Photo : Flickr, "it was 3 a.m.") Pot's constituent molecules kill bacteria and inhibit the formation of prions, a protein that can cause neurodegenerative diseases.

“New research reveals that several marijuana ingredients exhibit a potent antibiotic capacity in cases of methicillin-resistant Staphylococcus aureus (MRSA) infections as well as the ability to fight off proteins called prions that can lead to Mad Cow disease and Creutzfeld-Jakob disease (CDJ).”

More: http://www.medicaldaily.com/articles/17941/20130730/marijuana-mrsa-prions-mad-cow-disease.htm

Cannabis abuse is associated with better emotional memory in schizophrenia: A functional magnetic resonance imaging study.

 “…we performed a functional magnetic resonance imaging study of emotional memory in schizophrenia patients with cannabis abuse…

  These results are consistent with previous findings showing that cannabis abuse is associated with fewer negative symptoms and better cognitive functioning in schizophrenia…”

http://www.ncbi.nlm.nih.gov/pubmed/23906663

Cannabidivarin-rich cannabis extracts are anticonvulsant in mouse and rat via a CB1 receptor-independent mechanism.

“Epilepsy is the most prevalent neurological disease and is characterised by recurrent seizures. Here we investigate: (i) the anticonvulsant profiles of cannabis-derived botanical drug substances (BDS) rich in cannabidivarin (CBDV) and containing cannabidiol (CBD) in acute in vivo seizure models and (ii) the binding of CBDV BDSs and their components at cannabinoid CB1 receptors.

CDBV BDSs exerted significant anticonvulsant effects… 

CONCLUSIONS AND IMPLICATIONS:

CBDV BDSs exerted significant anticonvulsant effects in three models of seizure that were not mediated by the CB1 cannabinoid receptor, and were of comparable efficacy to purified CBDV.

These findings strongly support the further clinical development of CBDV BDSs for treatment of epilepsy.”

http://www.ncbi.nlm.nih.gov/pubmed/23902406

“Cannabidivarin is anticonvulsant in mouse and rat… These results indicate that CBDV is an effective anticonvulsant in a broad range of seizure models.”  http://www.ncbi.nlm.nih.gov/pubmed/22970845

THC, found in cannabis, shown to be effective in the treatment of brain tumors

“In 2000, scientists at the Complutense University of Madrid carried out an extensive experiment, testing the effects of THC on cancerous brain cells in laboratory rats. Their discoveries were nothing short of amazing, as THC had effectively managed to destroy all cancer cells, while leaving healthy cells unaffected.
 
 Research into the effects of THC on glioblastoma would have had the potential to revolutionize available cancer treatments, yet due to insufficient funding and poor public exposure, the science team was unable to further their research.Manuel Guzman explained that “cannabinoids are selective antitumor compounds, as they can kill tumor cells without affecting their non-transformed counterparts.” In contrast to this, chemotherapy, the prevalent anticancer treatment of today, consists of a combination of antineoplastic drugs that have devastating physical and psychological side-effects… 
 
THC works by triggering the build-up of a chemical messenger known as ceramide, which in turn induces apoptosis (or programmed cell death) in mutated tumor cells.
Subsequent research into the properties of THC has revealed that it is among the very few naturally occurring, harmless substances that are capable of inducing programmed cell death in cancerous cells. Other substances with this property include anandamide, other cannabinoids and tumor necrosis factors produced by the immune system in its attempt to fight cancer.
 
After months of effort to obtain funding for testing the medical effects of THC on human tissues, the Madrid science team was forced to abandon this project, although there is currently no effective treatment available for malignant brain tumors.”