Marijuana Smokers Found to Have Lower Risk of Diabetes, Research

Marijuana Smokers Found to Have Lower Risk of Diabetes, Research

“A new research has found that the people who smoke cannabis are having lower risk of suffering from diabetes. The researchers have said that the reason behind the same is that the people using marijuana have lower levels of insulin in blood.

This means that the blood sugar control is better in them. The link between cannabis and diabetes control is yet to be established. If it happens, a new development can be expected to treat the patients with the condition using the plant’s compound active ingredient, tetrahydrocannabinol, or THC.

The study was published in the American Journal of Medicine. It asserted that the people who consumed cannabis had 16% lower fasting of the insulin levels in comparison to those who had never smoked marijuana.

Also, the people using the drug were found to have lower waist circumference. Studies have found large waist circumference linked to diabetes risk.

Usually, marijuana is consumed by the cancer patients and others with conditions like multiple sclerosis. Medical form of the drug is legal for use in the 18 US states and most of the Americans want it to be legalized.

The findings were based on questionnaire answered by about 4,657 patients and the data derived from the National Health and Nutrition Survey between 2005 and 2010.”

http://frenchtribune.com/teneur/1318085-marijuana-smokers-found-have-lower-risk-diabetes-research

Scientist: Marijuana May Treat Diabetes – Fox News

“Cannabis plant extracts could potentially form the basic ingredients for a market-leading diabetes drug, the scientist who developed a former world-beating treatment for the condition believes…

“There really have been relatively few developments in finding new diabetes drug treatments… This new approach might be more productive in answering the unmet clinical need.””

Read more: http://www.foxnews.com/story/0,2933,526853,00.html

 

Marijuana Users Have Better Blood Sugar Control: Study

“Regular marijuana use has a positive effect on diabetic control, say researchers. They found that current marijuana users had significantly lower fasting insulin and were less likely to be insulin resistant, even after excluding patients with a diagnosis of diabetes mellitus. Their findings are reported in the current issue of The American Journal of Medicine.
 
Marijuana (Cannabis sativa) has been used for centuries to relieve pain, improve mood, and increase appetite. Outlawed in the United States in 1937, its social use continues to increase and public opinion is swinging in favor of the medicinal use of marijuana…”
 

Cannabis linked to prevention of diabetes

“Regular users of the drug found to have lower levels of insulin after fasting, research shows. Smoking cannabis may prevent the development of diabetes, one of the most rapidly rising chronic disorders in the world.

If the link is proved, it could lead to the development of treatments based on the active ingredient of cannabis, tetrahydrocannabinol (THC), without its intoxicating effects.”

Read more: http://www.independent.co.uk/life-style/health-and-families/health-news/cannabis-linked-to-prevention-of-diabetes-8616314.html

Marijuana Can Help Prevent Suicide, Study Suggests

“Marijuana does many magical things, not the least of which is make dubstep listenable. In Los Angeles, we use it pretty much legally for back pain, nausea and hot tubbing.

But a new study from Germany says that, in U.S. states like California where marijuana has become medically legit, rates of suicide have gone down.

The researchers note that suicide is often triggered by “stressful life events.” And you know what can take away the pain?

No. Not Enrique Iglesias. Stress! Or rather, chronic. Depending.

The academics note that “California includes anxiety as a qualifying condition” to obtain medical pot, “while Delaware and New Mexico both allow the use of medical marijuana for post traumatic stress disorder … ”

The Institute for the Study of Labor (IZA) in Bonn, with the help of American researchers such as Daniel I. Rees of the University of Colorado’s Department of Economics, recently published their findings in a paper called High on Life? Medical Marijuana Laws and Suicide (PDF):

Our results suggest that the passage of a medical marijuana law is associated with an almost 5 percent reduction in the total suicide rate, an 11 percent reduction in the suicide rate of 20- through 29-year-old males, and a 9 percent reduction in the suicide rate of 30- through 39-year-old males.

The study takes some wild guesses, and one of them is that maybe medical marijuana users are cutting out the alcohol, which can be depressive:

The strong association between alcohol consumption and suicide related outcomes found by previous researchers (Markowitz et al. 2003; Carpenter 2004; Sullivan et al. 2004; Rodriguez Andres 2005; Carpenter and Dobkin 2009) raises the possibility that medical marijuana laws reduce the risk of suicide by decreasing alcohol consumption.

The academics cite research on animals where there was “a potent anti-depressant effect” when they were injected with low doses of synthetic cannabinoid.

Of course this flies in the face of tons of research — not to mention what Dr. Drew Pinsky has said several times — that cannabis and depression go together like milk and cookies.

And, it seems clear to us, the only solid argument to be made here is there might be a correlation between medical marijuana states and lower rates of suicides.

Hmm. National suicide rates have been decreasing across the board.

Researchers say they focused mostly on young men because most medical marijuana patients in states like Arizona, Colorado and Montana are males, and roughly half are under 40. Data on women, apparently, was weak. (Women are four times less likely to commit successful suicide in general).

The German study’s rosy conclusion:

… The legalization of medical marijuana leads to an improvement in the psychological well being of young adult males, an improvement that is reflected in fewer suicides.

Believe that. Or not.”

By Dennis Romero

http://blogs.laweekly.com/informer/2012/02/marijuana_suicide_medical_states_california.php

Cannabis-based drugs could offer new hope for inflammatory bowel disease patients

“Researchers investigating anecdotal evidence that cannabis relieves some of the symptoms of inflammatory bowel disease (IBD) have discovered a potential new target for cannabis-derived drugs for treatment of the disease.

This finding, published in the journal Gastroenterology… could bring new hope for… sufferers of diseases like Crohn’s and ulcerative colitis1 with the possibility that cannabis-derived drugs may help to heal the gut lining, which is damaged during the course of disease. ”

Read more: http://www.medicalnewstoday.com/releases/28584.php

Cannabis for Ulcerative Colitis and Crohn’s Disease treatment

“Chemicals found in cannabis could prove an effective treatment for the inflammatory bowel diseases Ulcerative Colitis and Crohn’s Disease, say scientists.

Laboratory tests have shown that two compounds found in the cannabis plant – the cannabinoids THC and cannabidiol – interact with the body’s system that controls gut function.

Crohn’s Disease and Ulcerative Colitis, which affect about one in every 250 people in Northern Europe, are caused by both genetic and environmental factors. The researchers believe that a genetic susceptibility coupled with other triggers, such as diet, stress or bacterial imbalance, leads to a defective immune response.

Dr Karen Wright, Peel Trust Lecturer in Biomedicine at Lancaster University, will be presenting her soon-to-be published work at The British Pharmacological Society’s Winter Meeting in London today (Thursday).

She said: “The lining of the intestines provides a barrier against the contents of the gut but in people with Crohn’s Disease this barrier leaks and bacteria can escape into the intestinal tissue leading to an inappropriate immune response.

“If we could find a way to restore barrier integrity in patients we may be able to curb the inflammatory immune response that causes these chronic conditions.”

Dr Wright, working with colleagues at the School of Graduate Entry Medicine and Health in Derby, has shown that cells that react to cannabinoid compounds play an important role in normal gut function as well as the immune system’s inflammatory response.

“The body produces its own cannabinoid molecules, called endocannabinoids, which we have shown increase the permeability of the epithelium during inflammation, implying that overproduction may be detrimental,” said Dr Wright.

“However, we were able to reverse this process using plant-derived cannabinoids, which appeared to allow the epithelial cells to form tighter bonds with each other and restore the membrane barrier.”

The research was carried out using cell cultures in a dish but, interestingly, when the team attempted to mimic the conditions of the gut by reducing the amount of oxygen in the cells’ environment, much lower concentrations of cannabinoid were needed to produce the same effect.

Dr Wright added: “What is also encouraging is that while THC has psychoactive properties and is responsible for the ‘high’ people experience when using cannabis, cannabidiol, which has also proved effective in restoring membrane integrity, does not possess such properties.”

The British Pharmacological Society (BPS) – the primary UK learned society concerned with research into drugs and the way they work – is hosting its annual Winter Meeting in London, attracting experts from across the world.

The three-day conference, running from 15 to 17 December 2009, will hear presentations on the latest pharmacological developments to tackle a range of conditions and diseases.”

http://www.news-medical.net/news/20091217/Cannabis-for-Ulcerative-Colitis-and-Crohns-Disease-treatment.aspx

Cannabis Induces a Clinical Response in Patients with Crohn’s Disease: a Prospective Placebo-Controlled Study.

“The marijuana plant Cannabis sativa has been reported to produce beneficial effects for patients with inflammatory bowel diseases, but these have not been investigated in controlled trials. We performed a prospective trial to determine whether cannabis can induce remission in patients with Crohn’s disease…

Complete remission was achieved by 5/11 subjects in the cannabis group (45%)… Three patients in the cannabis group were weaned from steroid dependency. Subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.

CONCLUSION:

Although the primary endpoint of the study (induction of remission) was not achieved, a short course (8 week) of THC-rich cannabis produced significant clinical, steroid-free benefits to 11 patients with active CD, compared to placebo, without side effects.

Further studies, with larger patient groups and a non-smoking mode of intake, are warranted. ClinicalTrials.gov NCT01040910.”

http://www.ncbi.nlm.nih.gov/pubmed/23648372

Treatment of Crohn’s Disease with Cannabis: An Observational Study

“The marijuana plant cannabis is known to have therapeutic effects, including improvement of inflammatory processes. However, no report of patients using cannabis for Crohn’s disease (CD) was ever published.

OBJECTIVES:

To describe the effects of cannabis use in patients suffering from CD.

RESULTS:

Of the 30 patients 21 improved significantly after treatment with cannabis… The need for other medication was significantly reduced. Fifteen of the patients had 19 surgeries during an average period of 9 years before cannabis use, but only 2 required surgery during an average period of 3 years of cannabis use.

CONCLUSIONS:

This is the first report of cannabis use in Crohn’s disease in humans. The results indicate that cannabis may have a positive effect on disease activity, as reflected by reduction in disease activity index and in the need for other drugs and surgery. Prospective placebo-controlled studies are warranted to fully evaluate the efficacy and side effects of cannabis in CD.”

Full Text: http://www.ima.org.il/IMAJ/ViewArticle.aspx?year=2011&month=08&page=455

Cannabis use amongst patients with inflammatory bowel disease.

“Experimental evidence suggests the endogenous cannabinoid system may protect against colonic inflammation, leading to the possibility that activation of this system may have a therapeutic role in inflammatory bowel disease (IBD).

Medicinal use of cannabis for chronic pain and other symptoms has been reported in a number of medical conditions.

We aimed to evaluate cannabis use in patients with IBD…

CONCLUSION:

Cannabis use is common amongst patients with IBD for symptom relief, particularly amongst those with a history of abdominal surgery, chronic abdominal pain and/or a low quality of life index.

The therapeutic benefits of cannabinoid derivatives in IBD may warrant further exploration.”

http://www.ncbi.nlm.nih.gov/pubmed/21795981