“The hemp plant Cannabis sativa produces unique compounds known as cannabinoids, of which Δ9-tetrahydrocannabinol (THC) is the most important… The present study was undertaken to investigate the antitumoral action of cannabinoids in pancreatic cancer and the molecular mechanisms involved in that effect… Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes…These findings may contribute to set the basis for a new therapeutic approach for the treatment of pancreatic cancer.”
Tag Archives: Cannabinoids
Harvard Study: Marijuana Cuts Lung Cancer Tumor Growth In Half
“The active ingredient in marijuana cuts tumor growth in common lung cancer in half and significantly reduces the ability of the cancer to spread, say researchers at Harvard University who tested the chemical in both lab and mouse studies.”
http://www.sciencedaily.com/releases/2007/04/070417193338.htm
CANNABINOIDS: POTENTIAL ANTICANCER AGENTS
The study by Manuel Guzmán of Madrid Spain found that cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals. They do so by modulating key cell-signalling pathways, thereby inducing direct growth arrest and death of tumor cells, as well as by inhibiting the growth of blood vessels that supply the tumor.
The emerging role of the endocannabinoid system in cardiovascular disease
“… the EndoCannabinoid System has been implicated in a growing number of physiological functions of the nervous system and various peripheral organs, and its modulation turned out to hold tremendous therapeutic promise in a wide range of disparate diseases and pathological conditions, ranging from mood and anxiety disorders, movement disorders, neuropathic pain, multiple sclerosis, and spinal cord injury to cancer, glaucoma, osteoporosis, atherosclerosis, myocardial infarction, stroke, hypertension, and obesity/ metabolic syndrome to name just a few…”
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791499/?tool=pubmed
The endocannabinoid system in prostate cancer
“Accumulating evidence indicate that the endocannabinoid system is dysregulated in prostate cancer… Overexpression of several components of the endocannabinoid system correlate with prostate cancer grade and progression, potentially providing a new therapeutic target for prostate cancer… several cannabinoids exert antitumoral properties against prostate cancer, reducing xenograft prostate tumor growth, prostate cancer cell proliferation and cell migration… the therapeutic potential of cannabinoids against prostate cancer is very promising…”
Alzheimer’s disease; taking the edge off with cannabinoids?
“Thus, cannabinoids offer a multi-faceted approach for the treatment of Alzheimer’s disease by providing neuroprotection and reducing neuroinflammation, whilst simultaneously supporting the brain’s intrinsic repair mechanisms by augmenting neurotrophin expression and enhancing neurogenesis. The evidence supporting a potential role for the cannabinoid system as a therapeutic target for the treatment of Alzheimer’s disease will be reviewed herewith.”
http://www.medicalmarijuanainc.com/index.php/alzheimer-s-disease
Cannabidiol and other cannabinoids reduce microglial activation in vitro and in vivo: relevance to Alzheimer’s disease
“CBD is able to modulate microglial cell function in vitro and induce beneficial effects in an in vivo model of AD. Given that CBD lacks psychoactivity, it may represent a novel therapeutic approach for this neurological disease.”
http://www.medicalmarijuanainc.com/index.php/alzheimer-s-disease
Cannabis Science Presents Newest Photographs From 3rd Cancer Patient That Show Cancer Tumors Dying and Areas That Are Now Pain Free
January 30, 2012
“DENVER–(BUSINESS WIRE)– Cannabis Science, Inc. (OTCBB:CBIS.OB) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is pleased to share new photographs from this cancer patient with severe squamous cell carcinoma. These pictures clearly show that this patient, with previously treatment-resistant tumors, continues to make obvious improvement. The tumors appear to be dying and then healing after treatment with cannabis-based extracts.”
Cannabis Science Reports Apparent Success For 3rd Self-Medicated Cancer Patient
“Cannabis Science, Inc., a pioneering US biotech company developing pharmaceutical cannabis products, is happy to report an additional, apparently successful, self-medicated cannabis treatment for a cancer patient.
This case is very graphic in nature. One of the patient’s physicians said it was the worst case of squamous cell carcinoma cancer he had ever seen, while another refused to continue tending to the patient.
While this patient’s self-administered treatment with cannabis extracts is still in progress, the results after just two weeks of treatment are dramatic. Some of the tumors have disappeared and others have significantly shrunk to a fraction of their original size. Simultaneously, the patient has had a significant decrease in pain, improved sleeping (the 1st full night of sleep in 3 years), as well as relief from the symptoms of multiple sclerosis that the patient also suffers from. This self-treatment is a work in progress.”
Cannabis Science Publishes List of Over 800 Peer-Reviewed Cannabis and Cancer References From Scientists Around the World
“This list of peer-reviewed manuscripts, provides support for the anecdotal observations of an increasing number of patients claiming successful cancer treatment using medical cannabis extracts.”
“The scientific documentation of the anti-cancer and anti-metastatic properties of cannabinoids is a driving force behind behind our long-term goal, to make high quality, effective, reliable and safe cannabis extracts available to the public beyond the borders of current medical marijuana states.”