Curing addiction with cannabis medicines

“Smokers trying to quit in the future could do it with the help of cannabis based medicines, according to research from The University of Nottingham.

Teams of pharmacologists, studying the cannabis-like compounds which exist naturally in our bodies (endocannabinoids), are exploring the potential for medical treatment. This includes treating conditions as diverse as obesity, diabetes, depression and addiction to substances like nicotine.

Scientists have known about endocannabinoids since the mid-1990s. This led to an explosion in the number of researchers looking into the future medical uses of cannabinoids and cannabis compounds.

Dr Steve Alexander, Associate Professor in the School of Biomedical Sciences, focused on a number of these projects in editing the first themed podcast for the British Journal of Pharmacology.

Dr Alexander said: “It is clear that there is very realistic potential for cannabinoids as medicines. Scientists are looking at a range of possible applications.”

One of these researchers is Professor David Kendall, a cellular pharmacologist at the University: “The brain is full of cannabinoid receptors. And so, not surprisingly with diseases like depression and anxiety, there’s a great deal of interest in exploiting these receptors and in doing so, developing anti-depressant compounds.”

Addiction is a real target – researchers like Professor Kendall believe the endocannabinoids could be a crucial link to addictive behaviour: “We know that the endocannabinoid system is intimately involved in reward pathways and drug seeking behaviour. So this tends to indicate that that if the link involving endocannabinoids and the reward pathway, using inhibitors, can be interrupted, it could turn down the drive to seek addictive agents like nicotine.”

Because cannabinoids have also been shown to bring down blood pressure, it is hoped that related compounds can be used in patients with conditions like hypertension.

Dr Michael Randall, a cardiovascular pharmacologist at the University has looked at how endocannabinoids cause blood vessels to relax. “This could have many implications,” Dr Randall said. “The endocannabinoids appear to lower blood pressure under certain conditions; states of shock for example. If the endocannabinoids are of physiological importance, this could have real therapeutic possibilities.”

“In terms of getting better medicines the endocannabinoid system has a lot to offer,” said Dr Alexander. “The range of cannabis-related medicines is currently limited, but by increasing our knowledge in this area we can increase our stock.”

The University of Nottingham”

http://www.brightsurf.com/news/headlines/36296/Curing_addiction_with_cannabis_medicines.html

Medical Marijuana as Treatment for Alcoholism & Addiction

Medical marijuana is frequently in the news, and hopefully the growing awareness of the benefits of medical marijuana will lead to more sensible regulations and deeper research into why cannabis is so helpful in treating so many different conditions. Among the conditions that medical marijuana can treatis addiction, whether to drugs or alcohol.”

“Medical Marijuana as a Recovery Treatment”

“Marijuana as a recovery treatment is controversial, not least because there is conflicting research about whether medical marijuana is or is not addictive. However, many studies have found that medical marijuana is not addictive, or as harmful, as other drugs such as alcohol and opiates. Additionally, several studies have shown that marijuana can be an effective treatment for recovery from other substances.”

Read more: http://www.unitedpatientsgroup.com/blog/2012/07/26/medical-marijuana-as-treatment-for-alcoholism-addiction/

Marijuana To Control Alcohol Abuse

By Senior News Editor
Reviewed by John M. Grohol, Psy.D. on December 1, 2009

New Strategy Uses Pot To Control Alcohol Abuse “A new research effort has a provocative outcome as University of California-Berkeley researchers suggest substituting cannabis for treatment of heavy alcohol abuse.

Research published in BioMed Central’s open access Harm Reduction Journal features a poll of 350 cannabis users, finding that 40 percent used cannabis to control their alcohol cravings, 66 percent as a replacement for prescription drugs and 26 percent for other, more potent illegal drugs.

Amanda Reiman carried out the study at the UC-Berkeley Patient’s Group, a medical cannabis dispensary.

She said, “Substituting cannabis for alcohol has been described as a radical alcohol treatment protocol. This approach could be used to address heavy alcohol use in the British Isles – people might substitute cannabis, a potentially safer drug than alcohol with less negative side effects, if it were socially acceptable and available.”

Reiman found that 65 percent of people reported using cannabis as a substitute because it has fewer adverse side effects than alcohol, illicit or prescription drugs, 34 percent because it has less withdrawal potential and 57.4 percent because cannabis provides better symptom management.

Reiman believes this discovery brings up two important points.

“First, self-determination, the right of an individual to decide which treatment or substance is most effective and least harmful for them. Secondly, the recognition that substitution might be a viable alternative to abstinence for those who can’t or won’t completely stop using psychoactive substances.”

Speaking about legalization of cannabis, Reiman added, “The economic hardship of the Great Depression helped bring about the end of alcohol prohibition. Now, as we are again faced with economic struggles, the U.S. is looking to marijuana as a potential revenue generator.

“Public support is rising for the legalization of recreational use and remains high for the use of marijuana as a medicine. The hope is that this interest will translate into increased research support and the removal of current barriers to conducting such research, such as the Schedule I/Class B status of marijuana.””

http://psychcentral.com/news/2009/12/01/marijuana-to-control-alcohol-abuse/9863.html

Major Health Benefits of Medical Cannabis

“The benefits of medical marijuana plant are extensive, pervasive, and long-standing. Because of the way the cannabis impacts the Autonomic Nervous System which develops the breath and relaxes the body, prospective for health and curative characteristics are huge. Some of the major health benefits of medical cannabis are explained below:

Treats Migraines

Cannabis healing has been very effective in the treatment of migraine headaches. Migraine headaches are vascular in source and are often preceded by an air characterized by nausea, flashes of light, faintness or photosensitivity.

Slows Down Tumor Growth

Studies have shown that cannabis help in slow down the facsimile and slow down the production of cancer cells in body. It is also a natural antiemetic, which makes it effectual in plummeting the nausea and vomiting related with chemo and radiation therapies. So taking marijuana slows down the tumor growth too.

Relieves Symptoms of Chronic Diseases

Marijuana is one of the best natural pain relievers that can help sufferers of chronic pain live more relaxed lives. The side effects are often much less severe than the other common pain medications.

Prevents Alzheimer’s

Cannabis reduces the occurrence of depression in Alzheimer’s patients, which can help patients to keep up a higher level of brain function. That is a powerful way to keep patients performance for a longer time after the first onset of Alzheimer’s disease.

Treats Glaucoma

Some strains of this medicinal plant have been shown that, they are potentially decreasing the force that glaucoma can place on the optic nerve; thereby the patients can easily cut the critical condition by smoking or taking the marijuana edibles or medicines.

Prevents Seizures

Seizure is a kind of epilepsy which almost affects more than 2 millions of Americans and 30 millions of people worldwide. Epilepsy is a condition when some of the brain cells become abnormally excitable. People using marijuana to control epilepsy should be alert when there is any removal of any tablets which controls seizures may leave you more susceptible to the patient. Marijuana is no exception. Patients with epilepsy are advised to exercise caution when using oral THC because there is no enough sufficient knowledge about the convulsive or anti-convulsive properties of the single compound.

For ADD and ADHD

Many people who endure with ADD and/or ADHD find that medical cannabis recovers their knack to hub and their level of recital with definite tasks. There are no clinical studies on humans but there are some beginner studies have done on animals that point to less hyperactivity and impulsivity with the use of cannabinoids (the active medicines in cannabis).

Relieve PMS

Millions of women have an illness on Premenstrual Syndrome (PMS). PMS includes the symptoms of headaches, abdominal cramps, bloating and fluid retention. Many women report that they have tried several different medications but none as give any significant relief like Medical Marijuana. Cannabis medicine has shown to give symptomatic relief from all the unpleasant symptoms of PMS.

Calm Those With Tourette’s and OCD

Several psychological disorders have been known to be related with the medical benefits of marijuana as well. Taking weed of prescribed amount on regular basis can slow down the tics for those who are suffering from Tourette’s syndrome and Obsessive Compulsive Disorder (OCD). Yes some of the qualities in marijuana plant help the patient to calm themselves when any creation of intrusive thoughts which produces fear, uneasiness and abnormal behaviors.”

http://www.herbalmission.org/major-health-benefits-of-medical-cannabis.php

Endometriosis: Marijuana Treatment

“Dr. Phillip Leveque has spent his life as a Combat Infantryman, Physician, Toxicologist and Pharmacologist.

(MOLALLA, Ore.) – I don’t think I have to explain what this is to anybody. If you have it, you know it. Endometriosis is graded in stages I,II, III & IV, with stage I being “minimized” inconvenience while stage IV is severe and usually requires surgery.

As a physician, I had known about endometriosis for years and that some women become narcotic addicts because of it. Pre Menstrual Tension (PMS) may be concurrent though different and I had many PMS patients as well. Some of them became addicts also. I was not surprised when lady patients came to our clinics offering chart notes that they had been prescribed every conceivable analgesic and other medications but they also told me marijuana works better than any regular prescription.

I have a severe pain problem myself caused by too high of a concentration of spinal anesthesia. I got disgusted by the anesthesiologist telling me he didn’t cause it but I got a new understanding for patients in pain.

If the patient says marijuana works for pain, I believe them. Actually in Oregon about sixty percent of patients have some chronic pain syndrome of nerve, muscle, joint, bone, intestinal or genitourinary. It doesn’t seem to matter whatever the source of pain, the bottom line is that MJ gives relief.

I presume stage I endometriosis and minor PMS are effectively treated with aspirin-like drugs, but when the pain etc. is in the moderate/severe level, the ladies have found out by themselves that marijuana/cannabis is effective without the hazard of narcotic addiction or alcoholism.

The U.S. government publicizes that as many as 77 million Americans have used marijuana and perhaps ten million use it frequently.

Marijuana as folk medicine has been used in the U.S. since the middle 1800’s and probably in Mexico and Latin America since the Spanish introduced it in the late 1500’s.

It is no longer amazing to me when a patient tells me of some new disease for which they have discovered marijuana treatment is beneficial.

It is time the DEA and its hoodlums backed off and allow the therapeutic use of medical marijuana, as more and more people are reverting to this tried and true “folk medicine” everyday.”

http://www.salem-news.com/articles/january032008/endo_med_1308.php

Marijuana Compound Effective In Treating Tourette’s Syndrome, Study Says

“Thursday, 15 May 2003

Hanover, Germany: A primary compound in marijuana, delta-9-tetrahydrocannabinol (THC), is effective in reducing “tics” in patients suffering from Tourette’s Syndrome (TS), according to clinical trail data published in a recent edition of the Journal of Clinical Psychiatry. Tourette’s Syndrome is a complex neuropsychiatric disorder characterized by motor tics (sudden spasms especially in the facial muscles, neck and shoulders) and one or more vocal tics.

Twenty-four patients participated in the double-blind placebo-controlled trial over a period of six weeks. Treatment with up to 10 mg of THC resulted in significant improvement of tic severity, authors wrote. No serious adverse effects to the treatment were reported.

In a separate article published in Neuropsychopharmacology, authors elaborated, “No detrimental effect was seen on learning curve, interference, recall and recognition of word lists, immediate visual memory span, and divided attention” from THC during or after the treatment.

The 24-patient study confirmed previous smaller patient trials that also found THC to be effective in the treatment of tics and behavioral problems in patients with Tourette’s Syndrome.”

http://norml.org/news/2003/05/15/marijuana-compound-effective-in-treating-tourette-s-syndrome-study-says

Marijuana Successfully Treats Tourette’s Syndrome, Study Shows

“Thursday, 11 March 1999

German researchers report that the consumption of the marijuana compound THC alleviates symptoms of Tourette’s Syndrome. The researchers published their findings in this month’s issue of the American Journal of Psychiatry.

“Earlier reports suggested beneficial effects in Tourette’s syndrome when smoking marijuana,” the German research team wrote. “We report a successful treatment of Tourette’s syndrome with delta-9-tetrahydocannabinol, the major psychoactive ingredient of marijuana.”

Tourette’s syndrome is a complex neuropsychiatric disorder that is characterized by sudden spasms, so called “tics,” that occur especially in the face, neck, and shoulders.

The researchers found that a 25-year-old patient treated with 10 mg of THC experienced marked improvement of both vocal and motor tics associated with behavioral disorders. “The improvement began 30 minutes after treatment and lasted for about seven hours,” the researchers reported. “No adverse effects occurred.”

Researchers stated, “This is the first report of a successful treatment of Tourette’s syndrome with delta-9-THC.” They said they are planning to confirm their preliminary results in an upcoming double-blind, placebo controlled, crossover study.

NORML board member Dr. Lester Grinspoon of Harvard Medical School called inhaled marijuana’s effects on patients suffering from Tourette’s “impressive,” and said that the drug holds tremendous potential as a course of treatment for the disease.

For more information, please contact either Allen St. Pierre of The NORML Foundation @ (202) 483-8751 or NORML board member Dr. Lester Grinspoon of Harvard Medical School @ (617) 277-3621.”

http://norml.org/news/1999/03/11/marijuana-successfully-treats-tourette-s-syndrome-study-shows

The therapeutic potential of novel cannabinoid receptors.

Cover image

“Cannabinoids produce a plethora of biological effects, including the modulation of neuronal activity through the activation of CB(1) receptors and of immune responses through the activation of CB(2) receptors. The selective targeting of either of these two receptor subtypes has clear therapeutic value. Recent evidence indicates that some of the cannabinomimetic effects previously thought to be produced through CB(1) and/or CB(2) receptors, be they on neuronal activity, on the vasculature tone or immune responses, still persist despite the pharmacological blockade or genetic ablation of CB(1) and/or CB(2) receptors. This suggests that additional cannabinoid and cannabinoid-like receptors exist. Here we will review this evidence in the context of their therapeutic value and discuss their true belonging to the endocannabinoid signaling system.”  http://www.ncbi.nlm.nih.gov/pubmed/19248809

“The therapeutic potential of novel cannabinoid receptors”  http://www.sciencedirect.com/science/article/pii/S0163725809000266

Is The NFL’s Campaign For Breast Cancer Awareness Really A Scam?

“October is breast cancer awareness month, and with that, the NFL has decided to pitch in to raise both money and awareness for breast cancer research.

But how much of that money is actually going to find a cure for breast cancer? According to a report, not very much.

Every October, NFL teams sport pink shoes, gloves, towels, hats and shirts, all designed to raise money and awareness. The NFL’s fundraising effort is multifaceted: There’s the off-field auction of autographed NFL paraphernalia and there’s the NFL online store that entices shoppers to purchase officially licensed NFL breast cancer gear.

A report from Business Insider revealed that 5% of purchases of officially licensed gear go back to the American Cancer Society. The rest of the cash goes directly into the NFL’s pockets.

Through four seasons of this pink initiative, the NFL has raised just $3 million for breast cancer research. To put that into perspective, the NFL made $9.5 billion last year.”

http://chicago.cbslocal.com/2012/10/11/is-the-nfls-campaign-against-breast-cancer-really-a-scam/

The NFL’s Campaign Against Breast Cancer Is a Total Scam

 

The NFL's Campaign Against Breast Cancer Is a Total Scam“Have you noticed that during the month of October, the NFL suddenly becomes intensely concerned with making sure you’re aware of breast cancer? Pink jerseys! Huge Ass Pink Ribbons at midfield! Pink motherfucking cleats! Fans interested in aware-ing on their own can even click on over to the NFL’s store and purchase ugly pink crap of their own under the assumption that their good intentions will actually contribute to the fight against cancer. Well, I hate to burst your Pepto Bismo Pink bubble, wearers of dangly earrings that contain both ribbons and tiny footballs, but you’ve been had — the NFL’s Breast Cancer Awareness Month campaign does raise itsy bitsy amounts of money for the fight against cancer, but the amount of money it raises pales in comparison to the amount of money it raises for billionaire NFL owners.

The NFL claims that its pink philanthropy efforts “support the fight against breast cancer” by “promoting awareness” and providing funds to the American Cancer Society. But what they’re mostly promoting is, uh, buying NFL gear, the profits from which are overwhelmingly pocketed by the NFL.

According to Business Insider, the NFL’s October Breast Cancer Awareness Month fundraising effort is multi-pronged. There’s the on-field onslaught of pink (AWARENESS), the off-field auction of autographed or otherwise noteworthy NFL paraphernalia (MONEY FOR THE CURE!), and the part of the NFL store that entices shoppers to purchase officially licensed NFL breast cancer gear, a portion of which goes to FINDING A CURE. According to the League, 100% of the proceeds from the specialty auction go to the American Cancer Society, but the total percentage of purchases of officially licensed gear that actually goes to FINDING A CURE is actually kind of pathetic — 5%. If you want to look at this cynically, in a way, the on-field wearin’ o’ the pink serves as an ad to direct consumers to purchase pink fan items.

BUT WAIT, you might say, AT LEAST THEY’RE DOING SOMETHING. And 5% is still something! Well, kind of. As BI pointed out, if NFL products are sold at a 100% markup and only 5% of sale proceeds go to the American Cancer Society, then the NFL is pocketing 90% of sales of Breast Cancer Awareness products, many of which would not be purchased if they didn’t come with a promise that consumers were “helping.” And, more perspective: while the American Cancer Society isn’t, say, Komen, they still don’t use 100% of the money they receive to “fight” breast cancer. Only 70% of donations taken in by the organization go toward cancer research. So, if you spend $10 on pink stink from the NFL, only about 35 cents is going to finding a cure for breast cancer. And $4.50 goes right back to the NFL, where I like to imagine that it’s spent on gas for a Lake Minnetonka pleasure cruise. For the cure.

But what about awareness?! Surely the NFL is helping keep people aware and alert and vigilant that at any moment, breast cancer could be lurking around a corner in a dark alley waiting with a hot pink switchblade to steal your purse and boobs. The thing about awareness is that it’s all but impossible to quantify — and everyone knows about breast cancer. If you asked 100 people if they’re aware that breast cancer is a thing and that it’s almost impossible to predict and most often affects women, I’d bet that most of them would nod before slowly backing away from you. Breast cancer awareness is so ubiquitous that if deadly diseases attended the same high school, breast cancer would probably be voted prom queen. The “awareness” that comes from the NFL’s sales of pink branded items doesn’t justify the extent to which the league is taking advantage of consumers’ good intentions to pad their wallets. Even if no NFL player ever touched another pink thing again, Americans would go right on being aware of the disease. Unless the Buffalo Jills or New Orleans Saintsations cheerleaders are holding up signs that show women how to give themselves breast self-exams or tickets come with 5 page printouts of places low income women can obtain breast health screening for low or no cost, the type of awareness the NFL is providing is useless, vague garbage.

Since the program’s inception four years ago, the NFL has raised $3 million for breast cancer. In 2009, the League made $8.5 billion. Last year, they made $9.5 billion. Commissioner Roger Goodell has set a revenue goal of $25 billion per year by the year 2027. A million per year out of between $8.5 and $9.5 billion in revenues? Pardon me while I don’t slobber all over the NFL’s pink-drenched marketing campaign.

Want to cure breast cancer? Give directly to an organization that cures breast cancer, or to an advocacy group that seeks actual cures, not marketing and corporate profits. Besides, wearing those horrid pink NFL breast cancer rain boots actually causes cancer. Of the eyes.”

http://jezebel.com/5950971/the-nfls-campaign-against-breast-cancer-is-a-total-scam