Cannabinoid receptor activation correlates with the pro-apoptotic action of the β2-adrenergic agonist, (R,R’)-4-methoxy-1-naphthylfenoterol, in HepG2 hepatocarcinoma cells

“In the last several years, development of new CBR ligands has become an intense area in cancer research because of the role of the endocannabinoid system in the regulation of cell proliferation and apoptosis…

The therapeutic potential for synthetic small bivalent ligands holds great promise as new lead compounds in a wide range of disparate diseases.”

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464034/