Marijuana treatments for autoimmune disorders

“Researchers from the University of South Carolina say that tetrahydrocannabinol, the principal constituent of marijuana, may have another medical use – treating those with autoimmune disorders.

Tetrahydrocannabinol (THC) is known to have analgesic effects so can be used to treat pain. It also aids relaxation and can reduce feelings of nausea and stimulate appetite…

Now, a new study, published in the Journal of Biological Chemistry, explores how analgesicmicroRNAs are influenced by THC.

MicroRNAs (miRNAs) are small, single-stranded, non-coding RNAs that play a vital role in regulating gene expression. And the authors claim that the ability to alter miRNA expression may be the key to successful treatment for many autoimmune diseases, including multiple sclerosisarthritis and type 1 diabetes.”

More: http://www.medicalnewstoday.com/articles/269432.php

Harvard: Marijuana Doesn’t Cause Schizophrenia

Harvard: Marijuana Doesn't Cause Schizophrenia

“Good news for people who’ve worried that smoking too much marijuana (cannabis) — especially as a teenager — might lead to some dramatic problems in the future, even  schizophrenia.

New research from Harvard Medical School, in a comparison between families with a history of schizophrenia and those without, finds little support for marijuana use as a cause of schizophrenia.

“The results of the current study suggest that having an increased familial morbid risk for schizophrenia may be the underlying basis for schizophrenia in cannabis users and not cannabis use by itself,” note the researchers.”

More: http://psychcentral.com/news/2013/12/10/harvard-marijuana-doesnt-cause-schizophrenia/63148.html

“A controlled family study of cannabis users with and without psychosis.” http://www.ncbi.nlm.nih.gov/pubmed/24309013

Research Shows that Marijuana Kills Cancer Cells

The marijuana molecula cannabidiol. Cell studies show it to be an anti-cancer agent.

“New research published this month in the journal Anticancer Research concludes that certain non-psychoactive cannabinoids “resulted in dramatic reductions in [leukemia] cell viability” and “caused a simultaneous arrest at all phases of the [leukemia] cell cycle,” according to an abstract posted online.

Study author Wai Liu, a University of London – St. George’s medical school oncologist, tested six cannabinoids, together and independently, on leukemia cells.

Liu told US News the molecules had “potent anti-cancer activity” and, significantly, “target and switch off” chemical signals that promote cancer growth.

Liu’s research builds on what is now at least a decade of startling research showing marijuana molecules’ effects on cancer cells…

Drug law reform advocates note that the United States all but ceased medical research into the benefits of marijuana during the decades-long and ongoing drug war. Research, however, continues overseas.”

http://www.eastbayexpress.com/LegalizationNation/archives/2013/10/25/research-shows-that-marijuana-kills-cancer-cells

Marijuana Might Kill Cancer – Newsweek

“A new study suggests that several components of the cannabis plant slow or kill malignant cells.”
Pot

 “Recent research gives new hope and meaning to the phrase “medical marijuana.”

In a paper published in October’s Anticancer Research, Wai Liu, a senior research fellow at St. George’s University of London, reports that he found six cannabinoids – active components of the cannabis plant – that can slow or outright kill cancer cells.

Though THC is the main cannabinoid associated with marijuana and has been recognized to have a “really strong anti-cancer effect,” Liu says, “it’s not a good candidate for therapeutic use because of its psychoactive properties.”

He examined whether several lesser-known cannabinoids would impact the growth of leukemia cells both individually and in combination.

The result?

“They’re good at killing cancer cells,” he says. And “because they’re not psychoactive, you can actually have the benefits associated with anti-cancer technology but not have the feelings of high, which are associated with THC.””

More: http://www.newsweek.com/marijuana-might-kill-cancer-1289

Can Cannabis Cure Cancer? – Newsweek

“New study suggests that several cannabinoids slow or kill malignant cells.”

“Recent research gives new hope and meaning to the phrase “medical marijuana.”

In a paper published in October’s Anticancer Research, Wai Liu, a senior research fellow at St. George’s University of London, reports that he found six cannabinoids – active components of the cannabis plant – that can slow or outright kill cancer cells.”

More: http://mag.newsweek.com/2013/11/01/cannabis-cure-cancer.html

Marijuana & Brain Cancer: Why CBD Beats Gliomas

“A non-psychoactive chemical found in marijuana called cannabidiol (CBD) could offer an effective treatment for brain cancer and is potentially an effective anti-cancer drug in the management of gliomas, without side effects, according to a new study from a team of Investigators in Spain, Italy and Canada.

The results suggest that CBD helps battle brain cancer through a combination of anti-cancer effects at the molecular level.”

More: http://blog.sfgate.com/smellthetruth/2013/12/05/marijuana-brain-cancer-why-cbd-beats-gliomas/

Non-Hallucinogenic Cannabinoids Are Effective Anti-Cancer Drugs – ScienceDaily

“New research has shown that the non-hallucinogenic components of cannabis could act as effective anti-cancer agents.

The anti-cancer properties of tetrahydrocannabinol (THC), the primary hallucinogenic component of cannabis, has been recognised for many years, but research into similar cannabis-derived compounds, known as cannabinoids, has been limited.

The study was carried out by a team at St George’s, University of London. It has been published in the journal Anticancer Research.

The team, led by Dr Wai Liu and colleagues carried out laboratory investigations using a number of cannabinoids, either alone or in combination with each other, to measure their anti-cancer actions in relation to leukemia.

Of six cannabinoids studied, each demonstrated anti-cancer properties as effective as those seen in THC. Importantly, they had an increased effect on cancer cells when combined with each other.”

More: http://www.sciencedaily.com/releases/2013/10/131014094105.htm

Breast Cancer Patients Helped With Marijuana

breast cancer

“Marijuana has become more widely studied recently for its medicinal properties, but the area is no longer limited to people suffering from pain, nausea, vomiting, anxiety, sleeplessness or disease-induced anorexia. It has now been discovered that breast cancer patients are helped with marijuana through direct anticancer actions that the cannabis species is able to provide.”

More: http://guardianlv.com/2013/12/breast-cancer-patients-helped-with-marijuana/

New research shows marijuana compounds do fight cancer

The bracts surrounding a cluster of Cannabis sativa flowers are coated with cannabinoid-laden trichomes. (Photo: Wikimedia Commons)

“Debate is just beginning in Washington over how medical marijuana will be grown and distributed now that the rules for the recreational market are established. Meanwhile, research into medical benefits of compounds within the cannabis plant continues to show effectiveness.

Effectiveness against pain in its many forms and other side effects of major diseases – or the palliative side of marijuana use – have been pretty well established, but can marijuana directly take on a disease as big, scary and deadly as cancer?

“What we’ve shown using just a few of these (cannabis) compounds is that the effects against cancer are really profound. They really are,” said Dr. Wai Liu, a senior research fellow at St George’s University of London.

Anticancer success

Quick note: Cannabinoids are the chemicals in marijuana that have effects in the body, some have psychoactive (or make you high) effects such as THC, and others such as CBD don’t have psychoactive effects but do interact with the body’s “cannabinoid receptors.” There are more than 85 “cannabinoids” in marijuana.

Liu’s most recent published research “explored the activity of six cannabinoids, used both alone and in combination in leukaemic cells.” The research was published in Anticancer Research: International Journal of Cancer Research and Treatment.

He said the anticancer activity of THC has been “known for sometime” but that THC’s psychoactive effect or tendency to get you high limits its use as a cancer-fighting agent. That’s partly due to the negative social stigma about getting high and, of course, not everyone wants to experience a high.

So, he set out to explore the cancer fighting ability of other cannabinoids that don’t get you high.

“We have shown that these six other agents that lack psychoactivity are also just as effective as an anti-cancer agent,” he said. Chief among the six was cannabidiol or CBD.”

More: http://blog.seattlepi.com/marijuana/2013/10/22/new-research-shows-marijuana-compounds-do-fight-cancer/

Non-Hallucinogenic Cannabinoids Could Cure Cancer: Is A Cheap Anti-Cancer Drug On The Way?

Non-Hallucinogenic Cannabinoids

“Studies that support marijuana’s medicinal properties are met with a great deal of skepticism due to cannabis’ hallucinogenic effects. Researchers from St. George’s University of London have isolated six non-hallucinogenic cannabinoids that could lead to the development of effective anti-cancer medication.

“This study is a critical step in unpicking the mysteries of cannabis as a source of medicine,” explained the study’s lead researcher, Dr. Wai Liu. “The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising.””

More: http://www.medicaldaily.com/non-hallucinogenic-cannabinoids-could-cure-cancer-cheap-anti-cancer-drug-way-259962