Medical Cannabis Treatment for Cancer and HIV/AIDS ?

“Benefits of Medical Cannabis”

medical marijuana

“Today, there are at least 17 states, including the District of Colombia, where cannabis is legal. Ohio, South Carolina, Colorado, New Jersey, California, and Michigan are just a few states that garnered strong support in the legalization of  medical cannabis. In Illinois, a bill legalizing the use of  cannabis needed the signature of Gov Pat Quinn. The legislation was approved by House and Senate, permitting doctors to prescribe cannabis for cancer and patients with HIV/AIDS and other diseases…

There is now quantifiable evidence that cannabis is beneficial in treating many disorders…

Moreover, the Medical Cannabis Research and the University of California found out that cannabis can treat HIV/AIDS and multiple sclerosis symptoms. It can even benefit cancer patients to mitigate the unpleasant side effects of chemotherapy or as an alternative treatment for cervical cancer, breast cancer, prostate cancer, lung cancer, colorectal cancer, brain cancer, and leukemia.”

More: http://guardianlv.com/2013/05/medical-cannabis-treatment-for-cancer-and-hivaids/

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Scientists believe marijuana compound could fight cancer

“Scientists in California believe they may have discovered a compound in marijuana that can reduce the aggressiveness of some forms of cancer.

The San Francisco Gate reports on the data that has been years in the making. While marijuana has been shown to help reduce nausea and pain in cancer patients, scientists believe that a compound in marijuana has the ability to “turn off” the activity of a gene responsible for metastasis in breast and other types of cancers.

The research team is working out of San Francisco’s California Pacific Medical Center Research Institute and have been working for years on the study. The compound they’re focused on, called cannabidiol, does not produce the psychotropic high associated with marijuana.

Last year, the team published a small study showing the positive effects of cannabidiol on mice. New data is about to be released that expands upon the previous results that the researchers hope will help propel the study even further.

“The preclinical trial data is very strong, and there’s no toxicity. There’s really a lot of research to move ahead with and to get people excited,” said Sean McAllister, who is working alongside scientist Pierre Desprez in the study.

Desprez and McAllister believe that their merging of separate areas of study was serendipitous.

Desprez had been studying the protein ID-1, which he found to play an important role in how cancer could spread. McAllister, on the other hand, was focused on studying anabolic steroids in drug abuse. He soon became focused on with the role non-psychotropic cannabidiol, or CBD, interacts with cancer.

McAllister, after hearing an internal seminar from Desprez on his studies of ID-1, came up with the question “How effective would cannabidiol be on targeting metastatic cancer cells?”

The two then teamed up, with Desprez armed with ID-1 cancer-causing protein, and McAllister with CBD, his cancer-fighting compound.

For their experimentation, the doctors exposed ID-1 to CBD in a petri dish. In a shocking result, the ID-1, the cancer-causing protein, reverted to a normal state and stopped acting “crazy.”

“We thought we did the experiment the wrong way,” McAllister said of the overwhelming results.

However, their results proved to be consisted.

“I told Sean, ‘Maybe your drug is working through my gene,’ ” Desprez said.

What the researchers have discovered thus far in their research is that CBD turns off the overexpression of ID-1, which prevents it from traveling to foreign tissues. Thus, the metastasization – cancer’s fatal ability – is blocked.

In the wake of their positive results, the doctors were forced to emphasize that the CBD will only work in the presence of high levels of ID-1 and these do not include all cancerous tumors but, rather, aggressive, metastatic cells. High levels have been found in leukemia, colorectal, pancreatic, lung, ovarian, brain and other cancers.”
Read more: http://www.irishcentral.com/news/Scientists-believe-marijuana-compound-could-fight-cancer-170689736.html#ixzz29rQbc2oS

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NBC News Reports that Cannabidiol (CBD) “Turns Off” the Cancer Gene Involved in Metastasis Findings by Scientists at California Pacific Medical Center gives Scientific Support for Cannabis Science

“Cannabis Science (CBIS), a pioneering U.S. Biotech Company developing pharmaceutical products for global public health challenges, reports on a recent press release by the San Francisco NBC news, with new studies by Scientists at California Pacific Medical Center, which have shown that cannabidiol, (CBD -1.18%, news), has the ability to “turn off” a gene that causes breast and other types of cancers to metastasize, according to the San Francisco Chronicle newspaper.

NBC News reports, “The drug “has been shown to reduce pain and nausea” in cancer patients. AIDS patients also use cannabis to eat, sleep and otherwise be more functional. Turns out that cannabidiol has none of the psychotropic effects of marijuana as a whole. The researchers hope to move to clinical trials on humans soon to test the cannabidiol inhibition of metastasis, reported in the San Francisco Chronicle. “What they found is that the cannabinoid turns off the overexpression of ID-1, which makes the cells lose their ability to travel to distant tissues. In other words, it keeps the cells more local and blocks their ability to metastasize. (spread to a new location) The researchers stressed cannabidiol works only on cancer cells that have these high levels of ID-1 and these do not include all cancerous tumors but, rather, aggressive, metastatic cells. But they’ve found such high levels in leukemia, colorectal, pancreatic, lung, ovarian, brain and other cancers.””

http://money.msn.com/business-news/article.aspx?feed=BW&date=20120920&id=15582334

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Cannabis destroys cancer cells

“Scientists working in the UK have revealed that cannabis has the potential to destroy leukemia cells.

The team – based at Queen Mary’s School of Medicine and Dentistry in London – have followed up on their previous findings that the main active ingredient in cannabis, tetrahydrocannabinol (THC) has the potential to be used effectively against some forms of cancer.

THC has previously been shown to attack cancer cells by interfering with important growth-processing pathways, however its mechanism of doing so has remained a mystery. Now, Dr Liu and his colleagues, using microarray technology – allowing them to simultaneously detect changes in more than 18,000 genes in cells treated with THC – have begun to uncover the existence of processes through which THC can kill cancer cells and potentially promote survival.”

http://www.labnews.co.uk/news/cannabis-destroys-cancer-cells/

 

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THC From Cannabis Destroys Cancer Cells

“The study results strongly suggest that if taken regularly, cannabis oil may be able to induce remission in leukemia patients without the horrendous side effects typically associated with standard radio-chemical treatment options. Although this is only one such study, other similar studies have shown equally impressive results.

 Many of the active ingredients found in cannabis-derived drugs show exceptional promise in treating some of the greatest hurdles facing modern medical science. In addition to their aforementioned capacity for safely treating certain forms of deadly cancer, they also show great promise in alleviating autoimmune conditions such as rheumatoid arthritis, multiple sclerosis, and even inflammatory bowel disease. A growing number of experts also note their possible viability treating a range of neurological disorders including Alzheimer’s and Lou Gehrig’s disease.”

http://www.globalhealingcenter.com/natural-health/thc-from-cannabis-destroys-cancer-cells/

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NBC News Reports that Cannabidiol (CBD) “Turns Off” the Cancer Gene Involved in Metastasis Findings by Scientists at California Pacific Medical Center gives Scientific Support for Cannabis Science Initiatives

“cannabidiol, (CBD), has the ability to “turn off” a gene that causes breast and other types of cancers to metastasize, according to the San Francisco Chronicle newspaper.

“What they found is that the cannabinoid turns off the overexpression of ID-1, which makes the cells lose their ability to travel to distant tissues. In other words, it keeps the cells more local and blocks their ability to metastasize. (spread to a new location) The researchers stressed cannabidiol works only on cancer cells that have these high levels of ID-1 and these do not include all cancerous tumors but, rather, aggressive, metastatic cells. But they’ve found such high levels in leukemia, colorectal, pancreatic, lung, ovarian, brain and other cancers.””

http://www.cnbc.com/id/49106127/NBC_News_Reports_that_Cannabidiol_CBD_Turns_Off_the_Cancer_Gene_Involved_in_Metastasis_Findings_by_Scientists_at_California_Pacific_Medical_Center_gives_Scientific_Support_for_Cannabis_Science_Initiatives

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Cannabis plant extract ‘could stop aggressive cancers from spreading’

“A compound found in cannabis could halt the spread of many forms of aggressive cancer, scientists say.

Researchers found that the compound, called cannabidiol, had the ability to ‘switch off’ the gene responsible for metastasis in an aggressive form of breast cancer. Importantly, this substance does not produce the psychoactive properties of the cannabis plant.”

Read more: http://www.dailymail.co.uk/health/article-2206056/Cannabis-compound-stop-breast-cancer-spreading.html#ixzz29PKHhfoL
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Cannabis and tobacco smoke are not equally carcinogenic

“Cannabis and tobacco smoke are not equally carcinogenic… Cannabis smoke contains cannabinoids whereas tobacco smoke contains nicotine (plus added carcinogens). Available scientific data, that examines the carcinogenic properties of inhaling smoke and its biological consequences, suggests reasons why tobacco smoke, but not cannabis smoke, may result in lung cancer… Furthermore, compounds found in cannabis have been shown to kill numerous cancer types including: lung cancer, breast and prostate, leukemia and lymphoma, glioma, skin cancer, and pheochromocytoma…”-

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1277837/?tool=pubmed

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Cannabis-induced cytotoxicity in leukemic cell lines: the role of the cannabinoid receptors and the MAPK pathway

“We therefore investigated the role of the CB-Rs (CannaBinoid-Receptors) in mediating apoptosis in 3 leukemic cell lines… We have shown that THC is a potent inducer of apoptosis… THC-induced cell death…”

http://bloodjournal.hematologylibrary.org/content/105/3/1214.long

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