Knocking down the expression of adenylate cyclase-associated protein 1 inhibits the proliferation and migration of breast cancer cells.

“Adenylate cyclase-associated protein 1 (CAP1) is a conserved protein that was found to be up-regulated in breast cancer and related to the migration of breast cancer…

CAP1 might be a potential molecular targeted therapy for surgery and immune treatment.”

http://www.ncbi.nlm.nih.gov/pubmed/24509166

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It’s breast cancer awareness month. Please, BE AWARE:

Paraben Link To Breast Cancer

“Study links milk-producing protein to aggressive breast cancer”  http://www.nydailynews.com/life-style/health/milk-producing-protein-linked-aggressive-breast-cancer-article-1.1228901

“Lactation may be Linked to Aggressive Breast Cancer” http://www.medindia.net/news/lactation-may-be-linked-to-aggressive-breast-cancer-125819-1.htm

“Lactation linked to reduced estrogen receptor-negative, triple-negative breast cancer risk”  http://medicalxpress.com/news/2014-09-lactation-linked-estrogen-receptor-negative-triple-negative.html

“Lactation reduces breast cancer risk” http://www.figo.org/news/lactation-reduces-breast-cancer-risk-0014726

“Breast Cancer Risk Linked to Virus Found in Cattle”  http://www.livescience.com/52314-breast-cancer-risk-bovine-leukemia-virus.html

“BLV Virus in Cattle can Cause Breast Cancer in Humans: Study”  http://northerncalifornian.com/content/52797-blv-virus-cattle-can-cause-breast-cancer-humans-study

“Stress and Its Connection to Breast Cancer”  http://www.huffingtonpost.com/barbara-jacoby/stress-and-its-connection_b_8101534.html

“Activation of Stress Gene Linked to Spread of Breast Cancer” http://www.medindia.net/news/activation-of-stress-gene-linked-to-spread-of-breast-cancer-124044-1.htm

“Stress Linked to Aggressive Breast Cancer” http://psychcentral.com/news/2011/09/20/stress-linked-to-aggressive-breast-cancer/29596.html

“Breastfeeding May Cut Risk For Aggressive Breast Cancer In Black Women”  http://www.rttnews.com/2391242/breastfeeding-may-cut-risk-for-aggressive-breast-cancer-in-black-women.aspx?type=hnr

“Breast-Feeding Cuts ER-Neg Breast Cancer Risk in Black Women”  http://www.medscape.com/viewarticle/832227?src=rss

“Constant Use of Birth Control Pills Raises Risk of Breast Cancer” http://allafrica.com/stories/201409291755.html

“Breast cancer misdiagnoses cost $4 billion: Study” http://www.cnbc.com/2015/04/06/breast-cancer-misdiagnoses-cost-4-billion-study.html

“‘False-alarm mammograms’ linked to increased breast cancer risk” http://www.foxnews.com/health/2012/04/06/false-alarm-mammograms-linked-to-increased-breast-cancer-risk/

“Mammograms may not reduce breast cancer deaths” http://news.yahoo.com/mammograms-may-not-reduce-breast-cancer-deaths-193337369.html

“Mammograms May Boost Breast Cancer Risk for Some Women” http://abcnews.go.com/Health/CancerPreventionAndTreatment/mammograms-boost-breast-cancer-risk-women/story?id=17181774

“Mammograms, X-rays may increase breast cancer risk in some women with specific genetic mutations” http://www.cbsnews.com/8301-504763_162-57508217-10391704/mammograms-x-rays-may-increase-breast-cancer-risk-in-some-women-with-specific-genetic-mutations/

“Mammograms Linked With Unnecessary Breast Cancer Treatment: Study” http://www.huffingtonpost.com/2012/11/26/mammogram-unnecessary-breast-cancer-treatment-study_n_2192041.html

“Targeted Radiation for Breast Cancer May Cause More Complications” http://health.usnews.com/health-news/news/articles/2012/10/24/targeted-radiation-for-breast-cancer-may-cause-more-complications

“Shock study: Chemotherapy can backfire, make cancer worse by triggering tumor growth” http://www.nydailynews.com/life-style/health/shock-study-chemotherapy-backfire-cancer-worse-triggering-tumor-growth-article-1.1129897

“Prophylactic Mastectomy Offers Minimal Gain in Breast Cancer”
http://www.medscape.com/viewarticle/812261
“Contralateral prophylactic mastectomy may not significantly increase life expectancy” http://medicalxpress.com/news/2013-10-contralateral-prophylactic-mastectomy-significantly-life.html

“New findings show preemptive mastectomies MAY NOT prevent breast cancer” http://pix11.com/?external_media=new-findings-show-preemptive-mastectomies-may-not-prevent-breast-cancer#axzz2hVJygdk9

“Life Expectancy Might Not Increase Upon Undergoing Contralateral Prophylactic Mastectomy” http://www.medindia.net/news/life-expectancy-might-not-increase-upon-undergoing-contralateral-prophylactic-mastectomy-126320-1.htm

“Study: Many breast cancer patients opt for unnecessary preventative mastectomies” http://www.cbsnews.com/8301-204_162-57603181/study-many-breast-cancer-patients-opt-for-unnecessary-preventative-mastectomies/

“New study finds cancer survivors should keep healthy breasts”  http://wtvr.com/2014/09/26/cancer-survivors-should-keep-healthy-breasts/

“More Younger Women Being Diagnosed with Metastatic Breast Cancer”
http://www.breastcancer.org/research-news/20130228

“Study: Breast Cancer Rates Rising in Young Women” http://radio.foxnews.com/2013/02/27/study-breast-cancer-rates-rising-in-young-women/

“Deadly breast cancers are rising in young women”
http://www.usatoday.com/story/news/nation/2013/02/26/breast-cancers-young-women/1949157/

“Advanced breast cancer on the rise in young women, study finds”
http://www.cbsnews.com/8301-204_162-57571448/advanced-breast-cancer-on-the-rise-in-young-women-study-finds/

“Report: Breast cancer incidence rates converging among white and African-American women”
http://medicalxpress.com/news/2013-10-breast-cancer-incidence-converging-white.html

“Most Common Breast Cancer on the Rise in US” http://www.livescience.com/15271-common-breast-cancer-rise.html

“Breast cancer rates rising in African American women” http://www.examiner.com/article/breast-cancer-rates-rising-african-american-women

“Breast Cancer Rates On The Rise In Black Women, And More Health News This Week” http://www.huffingtonpost.com/2013/10/04/breast-cancer-black-women-health-news-this-week_n_4043256.html

“Breast cancer rates rising in black women: Report”
http://www.cbsnews.com/8301-204_162-57605660/breast-cancer-rates-rising-in-black-women-report/

“Genetics may fuel aggressive breast cancers in black women” http://articles.philly.com/2015-09-06/news/66271522_1_brca-mutations-breast-cancer-african-american-women

“Blood pressure meds linked to raised breast cancer risk” http://www.cbsnews.com/8301-204_162-57597082/blood-pressure-meds-linked-to-raised-breast-cancer-risk/

“Some Antihypertensives Linked to Breast Cancer Risk” http://www.medscape.com/viewarticle/808935

“Channel Blockers for Blood Pressure Linked to Breast Cancer Risk, Study Finds” http://www.nlm.nih.gov/medlineplus/news/fullstory_139465.html

“Blood pressure drugs linked to higher breast cancer risk” http://www.medicalnewstoday.com/articles/264446.php

“Prescription drugs cause more deaths than breast cancer, car crashes in state”  https://badgerherald.com/news/2015/09/17/prescription-drugs-cause-more-deaths-than-breast-cancer-car-crashes-in-state/

“Research shows antidepressant Paxil may cause breast cancer” http://www.commdiginews.com/news-2/research-shows-antidepressant-paxil-may-cause-breast-cancer-9562/

“Deodorant Linked To Breast Cancer According To New Studies” http://foodworldorder.blogspot.com/2013/09/deodorant-linked-to-breast-cancer.html

“Aluminum in Deodorant Linked to Breast Cancer in New Studies” http://sorendreier.com/aluminum-in-deodorant-linked-to-breast-cancer-in-new-studies/

“New Paraben ‘Link’ To Breast Cancer Risks” http://www.huffingtonpost.co.uk/2012/01/12/paraben-chemical-linked-to-breast-cancer_n_1202144.html

“Parabens found in food linked to breast cancer” http://www.healthindex.co.uk/medical-news/parabens-found-in-food-linked-to-breast-cancer/

 “Breast cancer ‘linked’ to chemical jobs, Stirling study suggests” http://www.bbc.co.uk/news/uk-scotland-tayside-central-20366589

“Study: Lejeune Male Breast Cancer, Water Pollutants May Be Associated” http://www.military.com/daily-news/2015/09/23/study-lejeune-male-breast-cancer-water-pollutants-associated.html

“Pre-childbirth solvent exposure raises breast cancer risk”  http://www.rsc.org/chemistryworld/2014/06/organic-solvent-exposure-breast-cancer-risk-childbirth

“17 Everyday Chemicals Could Be Linked to Breast Cancer” http://time.com/95915/breast-cancer-chemicals/

“Air pollution linked to breast cancer, study suggests” http://www.sciencedaily.com/releases/2010/10/101006104003.htm

“New Study Links Plastics Exposure to Breast Cancer” http://www.motherjones.com/environment/2012/11/report-plastics-breast-cancer-link

“Chemical exposures of women workers in the plastics industry with particular reference to breast cancer and reproductive hazards.”  http://www.ncbi.nlm.nih.gov/pubmed/23207955

“Auto plastics industry linked to breast cancer, new study shows”  http://www.thestar.com/news/canada/2012/11/19/auto_plastics_industry_linked_to_breast_cancer_new_study_shows.html

“Plastics Chemical Promotes Breast Tumors: Study” http://www.newsmax.com/Health/Health-News/bpa-plastics-chemical-cancer/2014/03/07/id/556745/

“Researchers raise concerns about BPA and breast cancer”
http://www.usatoday.com/story/news/nation/2013/10/08/bpa-and-breast-cancer/2834461/
“BPA found to promote breast cancer in new study”
http://www.naturalnews.com/042331_BPA_breast_cancer_carcinogenic_chemicals.html
“Scientists find possible link between BPA and breast cancer” http://www.pentagonpost.com/scientists-find-link-bpa-breast-cancer/83412875
“Study: BPA Is in Wide Variety of Paper Products. Chemical Bisphenol A Is Found in Napkins, Toilet Paper, and Cash Register Receipts” http://www.webmd.com/cancer/news/20111202/study-bpa-is-in-wide-variety-of-paper-products?page=2
“Study: BPA Common in Kids’ Canned Foods. Researchers Say Potentially Harmful Chemical Is Leaching Into Soup From Cans”
http://www.webmd.com/parenting/news/20110920/study-bpa-common-in-kids-canned-foods
“Eating Fresh Foods May Cut Exposure to BPA. Study: Avoiding Packaged, Canned Foods May Reduce Levels of the Chemical Bisphenol A”
http://www.webmd.com/food-recipes/news/20110330/eating-fresh-foods-may-cut-exposure-to-bpa

“BPA may limit the effectiveness of commonly used anti-cancer drugs” http://www.cpmc.org/about/press/news2011/bisphenol-breastcells.html

 “Pesticide linked to breast cancerhttp://news.bbc.co.uk/2/hi/health/227178.stm

“Study links pesticide DDT to higher breast cancer risk” http://news.yahoo.com/study-links-pesticide-ddt-higher-breast-cancer-risk-154816085.html

“High traffic pollution ‘can double risk of breast cancer’ study finds”  http://www.dailymail.co.uk/health/article-1318343/High-pollution-double-risk-breast-cancer.html

“Breast Implants Linked To Rare Cancer Fda Says” http://news.us-daily.com/news/breast-implants-linked-to-rare-cancer-fda-says

“Rare cancer linked to breast implants” http://www.webmd.boots.com/cancer/news/20110128/rare-cancer-linked-to-breast-implants

“Bigger bra size ‘linked with breast cancer'” http://www.nhs.uk/news/2012/07July/Pages/bust-size-and-breast-cancer-risk.aspx

“No association found between wearing a bra and breast cancer”  http://www.oncologynurseadvisor.com/no-association-found-between-wearing-a-bra-and-breast-cancer/article/374319/

“Wearing a bra won’t give you breast cancer: study” http://www.nydailynews.com/life-style/health/bras-don-breast-cancer-study-article-1.1929184

“No, Wearing a Bra Will Not Give You Breast Cancer, Study Shows” http://time.com/3271011/bras-dont-cause-breast-cancer/

“Doctors: Women who store phone in bras at risk for breast cancer” http://wtvr.com/2012/11/19/doctors-women-who-store-phone-in-bras-at-risk-for-breast-cancer/

“Rat study suggests light at night might hamper breast cancer therapy”  http://www.ktbs.com/story/26655311/rat-study-suggests-light-at-night-might-hamper-breast-cancer-therapy

“Low Melatonin Raises Breast Cancer Risk” http://abcnews.go.com/Health/story?id=117176

“High cholesterol fuels the growth and spread of breast cancer” http://www.eurekalert.org/pub_releases/2013-11/dumc-hcf112113.php

“Cholesterol and fat in American diet fuels breast cancer” http://www.emaxhealth.com/1020/cholesterol-and-fat-american-diet-fuels-breast-cancer

“Healthy caffeine: Study proves coffee can ward off breast cancer” http://www.rt.com/news/251041-coffee-cancer-prevention-study/

“Coffee protects against breast cancer recurrence, detailed findings confirm”  http://www.sciencedaily.com/releases/2015/04/150421084531.htm

“Long-term night work linked to higher breast cancer risk” http://www.ctvnews.ca/health/health-headlines/long-term-night-work-linked-to-higher-breast-cancer-risk-1.1349734

“Night Shift Linked to Increased Breast Cancer Risk” http://hvilmia.ktvq.com/news/night-shift-linked-to-increased-breast-cancer-risk/

“Sleep Problems Linked to Aggressive Breast Cancer” http://psychcentral.com/news/2012/08/28/sleep-problems-linked-to-aggressive-breast-cancer/43772.html

“Good sleep may improve breast cancer survival” https://www.fredhutch.org/en/news/center-news/2015/06/good-sleep-may-improve-breast-cancer-survival.html

“Study Examines Link Between Breast Cancer and Diabetes” http://healthyliving.msn.com/diseases/breast-cancer/study-examines-link-between-breast-cancer-and-diabetes

“Sex hormones linked to breast cancer risk in women under 50” http://medicalxpress.com/news/2013-07-sex-hormones-linked-breast-cancer.html

“Hormone Therapy, Breast Cancer Link” http://www.cbsnews.com/video/watch/?id=6973527n

“Menopause Hormone Linked to Breast Cancer”   http://www.nytimes.com/1989/08/03/us/menopause-hormone-linked-to-breast-cancer.html

“Folic acid linked to breast cancer growth in animal study” http://www.medicalnewstoday.com/articles/271601.php

 “Mediterranean Diet With Olive Oil Linked to Lower Breast Cancer Risk”                            http://time.com/4033374/mediterranean-diet-breast-cancer/

“Olive oil may help prevent breast cancer” http://www.cnbc.com/2015/09/17/olive-oil-may-help-prevent-breast-cancer.html

“Can Flax Seeds Help Prevent Breast Cancer?” http://www.care2.com/greenliving/can-flax-seeds-help-prevent-breast-cancer.html

“Study: overnight fasting may reduce risk of breast cancer” http://www.kusi.com/story/28903328/study-overnight-fasting-may-reduce-risk-of-breast-cancer

“Alcohol Linked with Lobular Breast Cancer” http://news.cancerconnect.com/alcohol-linked-with-lobular-breast-cancer/

 “Breast Cancer Link To Alcohol Before Pregnancy” http://news.sky.com/story/1134459/breast-cancer-link-to-alcohol-before-pregnancy

 “Light drinking linked to breast cancer risk” http://usatoday30.usatoday.com/news/health/medical/health/medical/breastcancer/story/2011-11-01/Light-drinking-linked-to-slight-breast-cancer-risk/51030414/1

“UVic study links low-level alcohol consumption to breast cancer”  http://www.vancouversun.com/health/University+Victoria+study+links+level+alcohol+consumption+breast/10239787/story.html

“Even a little alcohol boosts risk of breast cancer: University of Victoria research”  http://metronews.ca/news/vancouver/1166517/even-a-little-alcohol-boosts-risk-of-breast-cancer-university-of-victoria-research/

“Study confirms breast cancer link to low alcohol use” http://medicalxpress.com/news/2014-09-breast-cancer-link-alcohol.html

“Moderate Drinking Increases Breast Cancer Risk” http://www.medpagetoday.com/HematologyOncology/BreastCancer/29392

“Heavy Drinking Raises Risk of Breast Cancer” http://www.tusaludmag.com/articles/Drinking_and_Cancer_2096_22191.shtml

 “Sugar Intake and Breast Cancer Risk”
http://health.yahoo.net/experts/breastcancer/sugar-intake-and-breast-cancer-risk

“Prolonged sitting linked to breast cancer, colon cancer” http://inthenews.mayoclinic.org/2011/11/03/prolonged-sitting-linked-to-breast-cancer-colon-cancer/

“Skirt size increase linked to breast cancer risk, says study” http://www.bbc.com/news/health-29351249

“DRUG MADE FROM HERBS MAY FIGHT BREAST CANCER”  http://www.futurity.org/breast-cancer-luteolin-998922/

“Cannabis compound ‘halts cancer'”
“A compound found in cannabis may stop breast cancer spreading throughout the body, US scientists believe.”  http://news.bbc.co.uk/2/hi/health/7098340.stm

“Increasing skirt size linked to breast cancer risk”  http://www.foxnews.com/health/2014/09/25/increasing-skirt-size-linked-to-breast-cancer-risk/

“Marijuana Compound May Stop Breast Cancer From Spreading, Study Says”  http://www.foxnews.com/story/2007/11/19/marijuana-compound-may-stop-breast-cancer-from-spreading-study-says/

“Obesity linked to recurrence of breast cancer” http://www.cbsnews.com/8301-18563_162-57501258/obesity-linked-to-recurrence-of-breast-cancer/

“Obesity a Risk Factor for Breast Cancer Deaths”  http://www.keyc.com/story/26551590/obesity-a-risk-factor-for-breast-cancer-deaths

“The fatter a woman becomes, the higher her risk of breast cancer”  http://www.wwl.com/The-fatter-a-woman-becomes-the-higher-her-risk-of-/20003707

“Obesity Fuels Breast Ca by Altering Tissue Microenvironment” http://www.clinicaloncology.com/ViewArticle.aspx?d=Web%2BExclusives&d_id=245&i=September+2015&i_id=1224&a_id=33552

“Exercise, weight control reduce risk of breast cancer” http://www.usatoday.com/story/news/nation/2013/10/01/breast-cancer-exercise-weight-control/2795127/

“Exercise Benefits Breast Cancer Patients” http://www.webmd.com/breast-cancer/news/20120415/exercise-benefits-breast-cancer-patients

“How Exercise May Reduce Breast Cancer Risk ” http://news.health.com/2013/04/09/new-clues-to-how-exercise-may-reduce-breast-cancer-risk/

“Exercise scores over diet in lowering breast cancer risk”  http://www.indiatvnews.com/lifestyle/news/exercise-is-the-best-way-to-cure-breast-cancer-risk-3562.html

“Control of Breast Cancer by the Endocannabinoid System”
http://grantome.com/grant/NIH/K01-CA111723-01A2

“Exercise activates the endocannabinoid system”
http://www.ncbi.nlm.nih.gov/pubmed/14625449

“The endocannabinoid system and cancer: therapeutic implication”
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165955/..

.”Exercise Helps Prevent Breast Cancer”
http://abcnews.go.com/Health/story?id=116923&page=

“Walking Can Reduce Breast Cancer Risk”
http://healthland.time.com/2013/10/04/walking-can-reduce-breast-cancer-risk/

“Breast Cancer May Be Linked to Digestion” http://www.care2.com/greenliving/breast-cancer-may-be-linked-to-digestion.html

“Design a healthy diet to help reduce breast cancer risk”  http://www.tauntongazette.com/article/20140930/LIFESTYLE/140939803

“Breast cancer risk may be lower for women with diverse gut bacteria”  http://www.oncologynurseadvisor.com/breast-cancer-risk-may-be-lower-for-women-with-diverse-gut-bacteria/article/371442/

“High fat diet linked to breast cancer” http://www.theguardian.com/uk/2003/jul/18/research.sciencenews

“High-fat diet during puberty linked to breast cancer risk later in life” http://phys.org/news202487777.html

“Starch intake linked to breast cancer risk” http://www.cbc.ca/news/health/starch-intake-linked-to-breast-cancer-risk-1.1081947

“Scientists from the University of Missouri in Columbia claim that luteolin, which occurs naturally in herbs and vegetables, can slow the development of breast cancer.” http://www.medicalnewstoday.com/articles/299389.php

“Certain Fruits and Vegetables Linked to Lower Breast Cancer Risk”  http://healthland.time.com/2012/12/07/certain-fruits-and-vegetables-linked-to-lower-breast-cancer-risk/

“Want To Lower Breast Cancer Risk? Eat Some Broccoli And Celery” http://www.techtimes.com/articles/84267/20150915/want-to-lower-breast-cancer-risk-eat-some-broccoli-and-celery.htm

“Broccoli Compound Found to Reduce Breast Cancer Risk” http://www.newsmax.com/Health/Health-News/breast-cancer-natural-broccoli/2015/09/10/id/684172/

“High fruit and vegetable intake has been linked with a reduced risk of breast cancer,” http://www.ncbi.nlm.nih.gov/pubmed/12704679

“Apples are recommended for breast cancer” http://foodforbreastcancer.com/foods/apples

“Drug Boosts Survival Against Type of Breast Cancer. Women with HER2-positive tumors gained an average 16 more months of life with Perjeta, study finds” http://www.webmd.com/breast-cancer/news/20140929/drug-gives-big-survival-boost-against-type-of-advanced-breast-cancer

“Natural compound attacks HER2 positive breast cancer cells. The compound is called psoralen, a natural component found in foods such as figs and celery,” http://www.sciencedaily.com/releases/2014/02/140217200755.htm

“Research finds link between chronic inflammation, tumor development in breast cancer”  http://www.local10.com/news/health/research-finds-link-between-chronic-inflammation-tumor-development-in-breast-cancer/33510556

Height linked to breast cancer risk” http://news.bbc.co.uk/2/hi/health/941890.stm

“Lack of sun exposure linked to breast cancer” http://www.abc.net.au/news/2012-10-24/breast-cancer-linked-to-amount-of-sun-exposure/4331772

“Hunger linked to increased risk of breast cancer in women” http://www.news-medical.net/news/20120926/Hunger-linked-to-increased-risk-of-breast-cancer-in-women.aspx

“U.S. Breast Cancer Cases Could Rise 50 Percent by 2030” http://consumer.healthday.com/cancer-information-5/breast-cancer-news-94/u-s-breast-cancer-cases-could-rise-50-percent-by-2030-698447.html

 “Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma.”” http://jpet.aspetjournals.org/content/318/3/1375.long

“Cannabinoids: a new hope for breast cancer therapy? … cannabinoids, the active components of Cannabis sativa… possess anticancer activity. Thus, these compounds exert anti-proliferative, pro-apoptotic, anti-migratory and anti-invasive actions in a wide spectrum of cancer cells… Moreover, tumor growth, angiogenesis and metastasis are hampered by cannabinoids… cannabinoid-based medicines may be useful for the treatment of most breast tumor subtypes.” http://www.ncbi.nlm.nih.gov/pubmed/22776349

“Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.” http://www.ncbi.nlm.nih.gov/pubmed/19887554

“Here, we show that Δ9-tetrahydrocannabinol (THC), through activation of CB2 cannabinoid receptors, reduces human breast cancer cell proliferation by blocking the progression of the cell cycle and by inducing apoptosis.”  http://www.ncbi.nlm.nih.gov/pubmed/16818634

“Programmed Cell Death (Apoptosis)” http://www.ncbi.nlm.nih.gov/books/NBK26873/

Δ9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation.. Taken together, these data might set the bases for a cannabinoid therapy for the management of breast cancer.”  http://cancerres.aacrjournals.org/content/66/13/6615.long

“Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition… ErbB2-positive breast cancer is characterized by highly aggressive phenotypes and reduced responsiveness to standard therapies…The purpose of this study was to determine whether cannabinoids might constitute a new therapeutic tool for the treatment of ErbB2-positive breast tumors… Our results show that both Delta9-tetrahydrocannabinol, the most abundant and potent cannabinoid in marijuana, and JWH-133, a non-psychotropic CB2 receptor-selective agonist, reduce tumor growth, tumor number, and the amount/severity of lung metastases… Histological analyses of the tumors revealed that cannabinoids inhibit cancer cell proliferation, induce cancer cell apoptosis, and impair tumor angiogenesis. Cannabinoid antitumoral action… these results provide a strong preclinical evidence for the use of cannabinoid-based therapies for the management of ErbB2-positive breast cancer.”  http://www.molecular-cancer.com/content/9/1/196

“Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents… not only as palliative but also as curative drugs.” http://www.ncbi.nlm.nih.gov/pubmed/19285265

“New Research Shows How Marijuana Compound Can Reduce Tumor Growth In Cancer Patients…THC, the major active component of marijuana, has anti-cancer properties,”  http://www.huffingtonpost.com/2014/07/16/marijuana-tumors_n_5588639.html

“Marijuana compound could help fight breast cancer” http://abclocal.go.com/kgo/story?id=5771385

“Cannabis Compound May Stop Metastatic Breast Cancer” http://abcnews.go.com/Health/Healthday/story?id=4509456

“Cannabis compound stops spread of breast cancer: researchers” http://www.cbc.ca/news/technology/cannabis-compound-stops-spread-of-breast-cancer-researchers-1.675379

Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells. Cyclooxygenase-2 (COX-2) is involved not only in inflammatory processes, but also in the metastasis of cancer cells… cannabidiolic acid (CBDA), a selective COX-2 inhibitor found in the fiber-type cannabis plant…Taken together, the results obtained here demonstrated that i) CBDA had dual inhibitory effects on COX-2 through down-regulation and enzyme inhibition, and ii) CBDA may possess the ability to suppress genes that are positively involved in the metastasis of cancer cells in vitro.”http://www.ncbi.nlm.nih.gov/pubmed/25242400

“Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis…Taken together, these lines of evidence in this study suggest that naturally occurring CBDA in cannabis is a selective inhibitor for COX-2.”  http://dmd.aspetjournals.org/content/36/9/1917.long

“Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration… Cannabidiol (CBD)… anti-proliferative effect on cancer cells…CBD is obtained from non-enzymatic decarboxylati…on of its parent molecule, cannabidiolic acid (CBDA)…The data presented in this report suggest for the first time that as an active component in the cannabis plant, CBDA offers potential therapeutic modality in the abrogation of cancer cell migration, including aggressive breast cancers.” http://www.ncbi.nlm.nih.gov/pubmed/22963825
“Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. Our data demonstrate the efficacy of CBD in pre-clinical models of breast cancer. CBD inhibits human breast cancer cell proliferation and invasion. The results have the potential to lead to the development of novel non-toxic compounds for the treatment of breast cancer…” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410650/

“Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy… In summary, we showed that CBD, a plant-derived cannabinoid, preferentially kills breast cancer cells…” http://mct.aacrjournals.org/content/10/7/1161.long

“Cannabidiol (CBD) Shown To Kill Breast Cancer Cells”  http://www.cafemom.com/group/99198/forums/read/19190923/Cannabidiol_CBD_Shown_To_Kill_Breast_Cancer_Cells

“Cannabis Kills Cancer Cells. Marijuana also found to prevent pain associated with chemotherapy”  http://guardianlv.com/2013/08/cannabis-kills-cancer-cells/

“Cannabis has been shown to kill cancer cells…” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page1

“…cannabinoids may be able to kill cancer cells while protecting normal cells… A laboratory study of delta-9-THC… showed that it damaged or killed the cancer cells…A laboratory study of cannabidiol… showed that it caused cancer cell death…” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page2

“Cannabinoids appear to kill tumor cells but do not effect their nontransformed counterparts and may even protect them from cell death.” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4

“Because cannabinoid receptors, unlike opioid receptors, are not located in the brainstem areas controlling respiration, lethal overdoses from Cannabis and cannabinoids do not occur.” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page6

“…our studies have identified Id-1 as a critical regulator of breast cancer progression and suggest the feasibility of developing novel therapeutic approaches to target Id-1 expression to reduce breast cancer metastasis in humans.” http://www.pnas.org/content/100/23/13543

“Recent Research on Cannabinoids. We targeted breast cancer cells that expressed high amounts of the protein Id-1. CBD is highly effective at turning off this specific gene that controls breast cancer metastasis.” http://www.cpmc.org/professionals/research/programs/science/cannabidiolarticles.html

“Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells… CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic breast cancer cells leading to the down-regulation of tumor aggressiveness…reducing Id-1 expression with cannabinoids could also provide a therapeutic strategy for the treatment of additional aggressive cancers because Id-1 expression was found to be up-regulated during the progression of almost all types…” http://mct.aacrjournals.org/content/6/11/2921.long

“Bay Area Researchers Claim Cannabis Can Cure Cancer” http://blogs.ocweekly.com/navelgazing/2013/04/bay_area_researchers_claim_can.php

“Cannabis oil stopped my cancer says Lake Macquarie’s Susannah Patch. A LAKE Macquarie woman whose ‘‘aggressive’’ breast cancer spread to various parts of her body including her spine and lungs credits her remarkable recovery to cannabis oil.”  http://www.theherald.com.au/story/2587931/cannabis-oil-stopped-my-cancer/?cs=12

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Evidence: Cannabinoid Therapy Reduces Breast Cancer Tumors

medical_cannabis.jpeg
 
“Warning: Many alternative treatments are shams with zero proof. Most alternatives make claims that are not backed up by any evidence or hard empirical medical studies, are are not peer-reviewed. 
 
Peer review means your study and its claims will be vetted by a panel of the best doctors and other medical professionals in that field, for critical review. They will try to find fault in its methodology before publication and its recommendations for possible human treatment.
 
For any cannabis-based study strong enough to stand up to this critical review, and for it to be published in a major journal within such a field as cancer research, is incredible. That’s exactly how strong the evidence for cannabis medicine is starting to become.
 
Imagine that. This plant, this “great friend of humanity” which has helped us survive by giving early humans food, fuel, fiber and medicine, and who ancient healers wrote about in 6000 B.C., more than 8,000 years ago, is now coming back to prove itself and to help save us again.
 
And this time we are starting to find the evidence to back up the claims made for this plant over the centuries…”
 
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Medical Cannabis Treatment for Cancer and HIV/AIDS ?

“Benefits of Medical Cannabis”

medical marijuana

“Today, there are at least 17 states, including the District of Colombia, where cannabis is legal. Ohio, South Carolina, Colorado, New Jersey, California, and Michigan are just a few states that garnered strong support in the legalization of  medical cannabis. In Illinois, a bill legalizing the use of  cannabis needed the signature of Gov Pat Quinn. The legislation was approved by House and Senate, permitting doctors to prescribe cannabis for cancer and patients with HIV/AIDS and other diseases…

There is now quantifiable evidence that cannabis is beneficial in treating many disorders…

Moreover, the Medical Cannabis Research and the University of California found out that cannabis can treat HIV/AIDS and multiple sclerosis symptoms. It can even benefit cancer patients to mitigate the unpleasant side effects of chemotherapy or as an alternative treatment for cervical cancer, breast cancer, prostate cancer, lung cancer, colorectal cancer, brain cancer, and leukemia.”

More: http://guardianlv.com/2013/05/medical-cannabis-treatment-for-cancer-and-hivaids/

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Cannabinoids may be therapeutic in breast cancer.

“Cannabinoids are a group of compounds synthesized exclusively by the Cannabis sativa plant, commonly known as marijuana. In 1990, the first cannabinoid-specific membrane (CB1) was characterized and cloned (Matsuda, Lolait, Brownstein, Young, & Bonner, 1990), which catapulted biomedical research on these unique compounds.

 Cannabinoids refer to both marijuana-derived compounds with the active ingredient of 9-tetrahydrocannabinol (THC) and also the synthetic molecules that activate the same primary targets as THC.

Therapeutic properties of marijuana have been well established; however, the clinical use of either plant-sourced or pure cannabinoids remains limited.

The anticachexia properties of cannabinoids are found in tetrahydrocannabinol (oral capsules of synthetically generated THC) and are used to manage weight loss, wasting syndrome, and nausea and vomiting associated with cancer treatment.”

http://www.ncbi.nlm.nih.gov/pubmed/23448745

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Role of cannabinoid and vanilloid receptors in invasion of human breast carcinoma cells.

“It is known that the diversified effects of cannabinoid on the fate of carcinoma cells are mediated predominantly through receptors. However, little is known about the effects of the individual activities of cannabinoid and noncannabinoid receptors. Here we investigate the role of cannabinoid receptor (CB) 1, CB2, and transient receptor potential vanilloid type 1 in cell proliferation and invasion patterns in the MDA-MB-231 cell line.

Our results showed that activation of CB1 and vanilloid receptors by methanandamide, a nonselective agonist, and arachidonyl-2′-choloroethylamide (ACEA) and N-oleoyldopamine, selective agonists, reduced invasion of MDA-MB-231 cells at pharmacological concentrations. Accordingly, CB1 activation resulted in decreased expression of matrix metalloproteinase (MMP) 2. On the other hand, administration of a CB2 agonist (CB65) increased cell invasion and expression of MMP2. The data obtained from MTT assay did not show any correlation between reduced invasion and cytotoxic effects of drugs. In addition, the level of vascular endothelial growth factor was significantly reduced in treatment with (R)-(+)-methanandamide, ACEA, CB65, and AM251 (a potent agonist for GPR55 and selective antagonist of CB1) compared with control. Elevated expression of cyclooxygenase-2 was observed in all of the MDA-MB-231 cells treated with agonists.

These results underline the influence of cannabinoid and vanilloid receptors on the invasiveness of MDA-MB-231 human breast carcinoma cells.”

http://www.ncbi.nlm.nih.gov/pubmed/23394450

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Cannabinoids Halt Pancreatic Cancer, Breast Cancer Growth, Studies Say

“Compounds in cannabis inhibit cancer cell growth in human breast cancer cell lines and in pancreatic tumor cell lines, according to a pair of preclinical trials published in the July issue of the journal of the American Association for Cancer Research.

In one trial, investigators at Complutense University in Spain and the Institut National de la Sante et de la Recherche Medicale (INSERM) in France assessed the anti-cancer activity of cannabinoids in pancreatic cancer cell lines and in animals. Cannabinoid administration selectively increased apoptosis (programmed cell death) in pancreatic tumor cells while ignoring healthy cells, researchers found. In addition, “cannabinoid treatment inhibited the spreading of pancreatic tumor cells … and reduced the growth of tumor cells” in animals.

“These findings may contribute to … a new therapeutic approach for the treatment of pancreatic cancer,” authors concluded.

In the second trial, investigators at Spain’s Complutense University reported that THC administration “reduces human breast cancer cell proliferation [in vitro] by blocking the progression of the cell cycle and by inducing apoptosis.” Authors concluded that their findings “may set the bases for a cannabinoid therapy for the management of breast cancer.”

Previous preclinical data published in May in the Journal of Pharmacological and Experimental Therapeutics reported that non-psychoactive cannabinoids, particularly cannabidiol (CBD), dramatically halt the spread of breast cancer cells and recommended their use in cancer therapy.

Separate trials have also shown cannabinoids to reduce the size and halt the spread of glioma (brain tumor) cells in animals and humans in a dose dependent manner. Additional preclinical studies have demonstrated cannabinoids to inhibit cancer cell growth and selectively trigger malignant cell death in skin cancer cells, leukemic cells, lung cancer cells, and prostate carcinoma cells, among other cancerous cell lines.”

http://norml.org/news/2006/07/06/cannabinoids-halt-pancreatic-cancer-breast-cancer-growth-studies-say

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Is The NFL’s Campaign For Breast Cancer Awareness Really A Scam?

“October is breast cancer awareness month, and with that, the NFL has decided to pitch in to raise both money and awareness for breast cancer research.

But how much of that money is actually going to find a cure for breast cancer? According to a report, not very much.

Every October, NFL teams sport pink shoes, gloves, towels, hats and shirts, all designed to raise money and awareness. The NFL’s fundraising effort is multifaceted: There’s the off-field auction of autographed NFL paraphernalia and there’s the NFL online store that entices shoppers to purchase officially licensed NFL breast cancer gear.

A report from Business Insider revealed that 5% of purchases of officially licensed gear go back to the American Cancer Society. The rest of the cash goes directly into the NFL’s pockets.

Through four seasons of this pink initiative, the NFL has raised just $3 million for breast cancer research. To put that into perspective, the NFL made $9.5 billion last year.”

http://chicago.cbslocal.com/2012/10/11/is-the-nfls-campaign-against-breast-cancer-really-a-scam/

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The NFL’s Campaign Against Breast Cancer Is a Total Scam

 

The NFL's Campaign Against Breast Cancer Is a Total Scam“Have you noticed that during the month of October, the NFL suddenly becomes intensely concerned with making sure you’re aware of breast cancer? Pink jerseys! Huge Ass Pink Ribbons at midfield! Pink motherfucking cleats! Fans interested in aware-ing on their own can even click on over to the NFL’s store and purchase ugly pink crap of their own under the assumption that their good intentions will actually contribute to the fight against cancer. Well, I hate to burst your Pepto Bismo Pink bubble, wearers of dangly earrings that contain both ribbons and tiny footballs, but you’ve been had — the NFL’s Breast Cancer Awareness Month campaign does raise itsy bitsy amounts of money for the fight against cancer, but the amount of money it raises pales in comparison to the amount of money it raises for billionaire NFL owners.

The NFL claims that its pink philanthropy efforts “support the fight against breast cancer” by “promoting awareness” and providing funds to the American Cancer Society. But what they’re mostly promoting is, uh, buying NFL gear, the profits from which are overwhelmingly pocketed by the NFL.

According to Business Insider, the NFL’s October Breast Cancer Awareness Month fundraising effort is multi-pronged. There’s the on-field onslaught of pink (AWARENESS), the off-field auction of autographed or otherwise noteworthy NFL paraphernalia (MONEY FOR THE CURE!), and the part of the NFL store that entices shoppers to purchase officially licensed NFL breast cancer gear, a portion of which goes to FINDING A CURE. According to the League, 100% of the proceeds from the specialty auction go to the American Cancer Society, but the total percentage of purchases of officially licensed gear that actually goes to FINDING A CURE is actually kind of pathetic — 5%. If you want to look at this cynically, in a way, the on-field wearin’ o’ the pink serves as an ad to direct consumers to purchase pink fan items.

BUT WAIT, you might say, AT LEAST THEY’RE DOING SOMETHING. And 5% is still something! Well, kind of. As BI pointed out, if NFL products are sold at a 100% markup and only 5% of sale proceeds go to the American Cancer Society, then the NFL is pocketing 90% of sales of Breast Cancer Awareness products, many of which would not be purchased if they didn’t come with a promise that consumers were “helping.” And, more perspective: while the American Cancer Society isn’t, say, Komen, they still don’t use 100% of the money they receive to “fight” breast cancer. Only 70% of donations taken in by the organization go toward cancer research. So, if you spend $10 on pink stink from the NFL, only about 35 cents is going to finding a cure for breast cancer. And $4.50 goes right back to the NFL, where I like to imagine that it’s spent on gas for a Lake Minnetonka pleasure cruise. For the cure.

But what about awareness?! Surely the NFL is helping keep people aware and alert and vigilant that at any moment, breast cancer could be lurking around a corner in a dark alley waiting with a hot pink switchblade to steal your purse and boobs. The thing about awareness is that it’s all but impossible to quantify — and everyone knows about breast cancer. If you asked 100 people if they’re aware that breast cancer is a thing and that it’s almost impossible to predict and most often affects women, I’d bet that most of them would nod before slowly backing away from you. Breast cancer awareness is so ubiquitous that if deadly diseases attended the same high school, breast cancer would probably be voted prom queen. The “awareness” that comes from the NFL’s sales of pink branded items doesn’t justify the extent to which the league is taking advantage of consumers’ good intentions to pad their wallets. Even if no NFL player ever touched another pink thing again, Americans would go right on being aware of the disease. Unless the Buffalo Jills or New Orleans Saintsations cheerleaders are holding up signs that show women how to give themselves breast self-exams or tickets come with 5 page printouts of places low income women can obtain breast health screening for low or no cost, the type of awareness the NFL is providing is useless, vague garbage.

Since the program’s inception four years ago, the NFL has raised $3 million for breast cancer. In 2009, the League made $8.5 billion. Last year, they made $9.5 billion. Commissioner Roger Goodell has set a revenue goal of $25 billion per year by the year 2027. A million per year out of between $8.5 and $9.5 billion in revenues? Pardon me while I don’t slobber all over the NFL’s pink-drenched marketing campaign.

Want to cure breast cancer? Give directly to an organization that cures breast cancer, or to an advocacy group that seeks actual cures, not marketing and corporate profits. Besides, wearing those horrid pink NFL breast cancer rain boots actually causes cancer. Of the eyes.”

http://jezebel.com/5950971/the-nfls-campaign-against-breast-cancer-is-a-total-scam

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Is the pink ribbon campaign a scam?

“The pink ribbon has become synonymous with solidarity for women who battle breast cancer. After all, a diagnosis of breast cancer changes the life of the diagnosed and the lives of all those involved — many times for the worse.

But, did you ever stop to think about what the pink ribbon campaign is all about? Is it really meant to bring “awareness” to breast cancer? Hasn’t everyone heard of breast cancer? Some have questioned the motives of those who stand behind those pretty pink ribbons.

Some have suggested that Breast Cancer Awareness month can be seen as a push for women to be corralled into the mammography suite so they can await their breast cancer diagnosis when the mammography is complete.

The science behind mammography is clear. Mammography does more harm than good.

Yes, the concept seems harsh. After all, most people who wear pink ribbons are innocent. They just go along with the rest. It’s a chance to show that they support the cause, whatever that is.

The pink ribbon campaign, however, is not completely innocent. Take for example this questionable involvement in the pink ribbon campaign. In October 2010, KFC filled and sold the “Bucket for the Cure,” donating 50 cents to breast cancer for each bucket sold. If KFC had a real interest for preventing breast cancer or for finding its cure, wouldn’t they close their doors forever? After all, the Physicians Committee for Responsible Medicine (PCRM) sued KFC for not disclosing to its customers that the chicken sold at KFC contained a dangerous carcinogen. “KFC should post warnings because its aggressively marketed new product harbors a chemical that increases the risk of breast cancer, prostate cancer, and other forms of this lethal disease,” commented Dr. Neal Barnard, of PCRM.

While some participants in the pink ribbon campaign do send raised funds to breast cancer charities, such as Komen for the Cure, others do not follow through with contributions. The Better Business Bureau has issued warnings to consumers regarding this shell game.

Pink Ribbons have hope. On the other hand, the entire breast cancer awareness initiative would be worthwhile if we continued to raise money to advertise the information that we already have about breast cancer prevention: diet, exercise, stress management prevent breast cancer. Why is it that people do not know that eating a low-fat whole plant foods diet is the single most important thing you can do to prevent breast cancer? Why don’t breast cancer organizations teach what we already know instead of continuing to look for a cure that comes in an expensive pill, treatment, or surgery?

Who’s benefiting here, anyway?”

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