Marijuana Might Kill Cancer – Newsweek

“A new study suggests that several components of the cannabis plant slow or kill malignant cells.”
Pot

 “Recent research gives new hope and meaning to the phrase “medical marijuana.”

In a paper published in October’s Anticancer Research, Wai Liu, a senior research fellow at St. George’s University of London, reports that he found six cannabinoids – active components of the cannabis plant – that can slow or outright kill cancer cells.

Though THC is the main cannabinoid associated with marijuana and has been recognized to have a “really strong anti-cancer effect,” Liu says, “it’s not a good candidate for therapeutic use because of its psychoactive properties.”

He examined whether several lesser-known cannabinoids would impact the growth of leukemia cells both individually and in combination.

The result?

“They’re good at killing cancer cells,” he says. And “because they’re not psychoactive, you can actually have the benefits associated with anti-cancer technology but not have the feelings of high, which are associated with THC.””

More: http://www.newsweek.com/marijuana-might-kill-cancer-1289

Marijuana & Brain Cancer: Why CBD Beats Gliomas

“A non-psychoactive chemical found in marijuana called cannabidiol (CBD) could offer an effective treatment for brain cancer and is potentially an effective anti-cancer drug in the management of gliomas, without side effects, according to a new study from a team of Investigators in Spain, Italy and Canada.

The results suggest that CBD helps battle brain cancer through a combination of anti-cancer effects at the molecular level.”

More: http://blog.sfgate.com/smellthetruth/2013/12/05/marijuana-brain-cancer-why-cbd-beats-gliomas/

Non-Hallucinogenic Cannabinoids Are Effective Anti-Cancer Drugs – ScienceDaily

“New research has shown that the non-hallucinogenic components of cannabis could act as effective anti-cancer agents.

The anti-cancer properties of tetrahydrocannabinol (THC), the primary hallucinogenic component of cannabis, has been recognised for many years, but research into similar cannabis-derived compounds, known as cannabinoids, has been limited.

The study was carried out by a team at St George’s, University of London. It has been published in the journal Anticancer Research.

The team, led by Dr Wai Liu and colleagues carried out laboratory investigations using a number of cannabinoids, either alone or in combination with each other, to measure their anti-cancer actions in relation to leukemia.

Of six cannabinoids studied, each demonstrated anti-cancer properties as effective as those seen in THC. Importantly, they had an increased effect on cancer cells when combined with each other.”

More: http://www.sciencedaily.com/releases/2013/10/131014094105.htm

Breast Cancer Patients Helped With Marijuana

breast cancer

“Marijuana has become more widely studied recently for its medicinal properties, but the area is no longer limited to people suffering from pain, nausea, vomiting, anxiety, sleeplessness or disease-induced anorexia. It has now been discovered that breast cancer patients are helped with marijuana through direct anticancer actions that the cannabis species is able to provide.”

More: http://guardianlv.com/2013/12/breast-cancer-patients-helped-with-marijuana/

New research shows marijuana compounds do fight cancer

The bracts surrounding a cluster of Cannabis sativa flowers are coated with cannabinoid-laden trichomes. (Photo: Wikimedia Commons)

“Debate is just beginning in Washington over how medical marijuana will be grown and distributed now that the rules for the recreational market are established. Meanwhile, research into medical benefits of compounds within the cannabis plant continues to show effectiveness.

Effectiveness against pain in its many forms and other side effects of major diseases – or the palliative side of marijuana use – have been pretty well established, but can marijuana directly take on a disease as big, scary and deadly as cancer?

“What we’ve shown using just a few of these (cannabis) compounds is that the effects against cancer are really profound. They really are,” said Dr. Wai Liu, a senior research fellow at St George’s University of London.

Anticancer success

Quick note: Cannabinoids are the chemicals in marijuana that have effects in the body, some have psychoactive (or make you high) effects such as THC, and others such as CBD don’t have psychoactive effects but do interact with the body’s “cannabinoid receptors.” There are more than 85 “cannabinoids” in marijuana.

Liu’s most recent published research “explored the activity of six cannabinoids, used both alone and in combination in leukaemic cells.” The research was published in Anticancer Research: International Journal of Cancer Research and Treatment.

He said the anticancer activity of THC has been “known for sometime” but that THC’s psychoactive effect or tendency to get you high limits its use as a cancer-fighting agent. That’s partly due to the negative social stigma about getting high and, of course, not everyone wants to experience a high.

So, he set out to explore the cancer fighting ability of other cannabinoids that don’t get you high.

“We have shown that these six other agents that lack psychoactivity are also just as effective as an anti-cancer agent,” he said. Chief among the six was cannabidiol or CBD.”

More: http://blog.seattlepi.com/marijuana/2013/10/22/new-research-shows-marijuana-compounds-do-fight-cancer/

Non-Hallucinogenic Cannabinoids Could Cure Cancer: Is A Cheap Anti-Cancer Drug On The Way?

Non-Hallucinogenic Cannabinoids

“Studies that support marijuana’s medicinal properties are met with a great deal of skepticism due to cannabis’ hallucinogenic effects. Researchers from St. George’s University of London have isolated six non-hallucinogenic cannabinoids that could lead to the development of effective anti-cancer medication.

“This study is a critical step in unpicking the mysteries of cannabis as a source of medicine,” explained the study’s lead researcher, Dr. Wai Liu. “The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising.””

More: http://www.medicaldaily.com/non-hallucinogenic-cannabinoids-could-cure-cancer-cheap-anti-cancer-drug-way-259962

The endocannabinoid system, cannabinoids, and pain.

“The endocannabinoid system is involved in a host of homeostatic and physiologic functions, including modulation of pain and inflammation… Exogenous plant-based cannabinoids (phytocannabinoids) and chemically related compounds, like the terpenes, commonly found in many foods, have been found to exert significant analgesic effects in various chronic pain conditions.

Currently, the use of Δ9-tetrahydrocannabinol is limited by its psychoactive effects and predominant delivery route (smoking), as well as regulatory or legal constraints.

 However, other phytocannabinoids in combination, especially cannabidiol and β-caryophyllene, delivered by the oral route appear to be promising candidates for the treatment of chronic pain due to their high safety and low adverse effects profiles.

This review will provide the reader with the foundational basic and clinical science linking the endocannabinoid system and the phytocannabinoids with their potentially therapeutic role in the management of chronic pain.”

http://www.ncbi.nlm.nih.gov/pubmed/24228165

Study: Marijuana Compound Can Kill Some Cancer Cells – TIME

Marijuana leaf

“Compounds derived from marijuana can kill cancerous cells in patients with leukemia, according to a recent study.

The study, published in the Anticancer Research journal, was partially funded by GW Pharmaceuticals. which already produces a cannabis-derived drug to help people with multiple sclerosis. Dr. Wai Liu studied six different non-psychoactive cannabinoids (compounds derived from marijuana that don’t get the user high like its THC component does). He found that certain non-psychoactive cannabinoids “resulted in dramatic reductions in cell viability” and “caused a simultaneous arrest at all phases of the cell cycle,” according to the study summary posted online.

Leukemia will take the lives of an estimated 23,720 people this year.

This isn’t the first time marijuana has been linked to deterring cancer: In 2012, researchers at the California Pacific Medical Center in San Francisco found that CBD — a non-psychoactive chemical compound found in cannabis — can stop metastasis in some kinds of aggressive cancer. Liu told the Huffington Post that smoking cannabis is unlikely to have the same cancer-inhibiting effect.”

http://healthland.time.com/2013/10/28/study-marijuana-compounds-can-kill-some-cancer-cells/

New Study: Cannabis May Help Cure Cancer

“A recent study shows that cannabis, at least its non-hallucinogenic elements, could serve as a valuable ally in not only treating cancer patients suffering from a myriad of debilitating symptoms, but it could also cure them of the deadly disease.

According to researchers at St. George Hospital Medical School, a subsidiary of the University of London, there is significant evidence that suggests certain cannabinoids found in marijuana could be used as a highly effective anti-cancer drug without patients being forced to experience the psychotropic effects of its use.

“This study is a critical step in unpicking the mysteries of cannabis as a source of medicine,” said Dr. Wai Liu, lead author of this research. “The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising. These agents are able to interfere with the development of cancerous cells, stopping them in their tracks and preventing them from growing. In some cases, by using specific dosage patterns, they can destroy cancer cells on their own.””

More: http://www.hightimes.com/read/new-study-cannabis-may-help-cure-cancer

Study: Cannabis Compounds Can Kill Cancer Cells – US News & World Report

“Researcher says cannabinoids might treat cancer as well as billion-dollar drugs.”

A medical marijuana activist holds a sign during a rally Jan. 4, 2010, in Oakland, Calif. Research suggests marijuana may fight cancer itself, not just side-effects.“A British researcher has found that cannabinoids, a term for chemicals derived from marijuana, can kill leukemia cells, and he expects clinical trials for new medications to begin soon.

The findings, published in the October issue of Anticancer Research: International Journal of Cancer Research and Treatment, show that certain non-psychoactive cannabinoids “resulted in dramatic reductions in cell viability” and “caused a simultaneous arrest at all phases of the cell cycle,” according to an abstract posted online. 

The study tested six cannabinoids, together and independently, on leukemia cells. Study author Wai Liu, an oncologist at the University of London’s St. George’s medical school, told U.S. News the chemicals displayed “potent anti-cancer activity” and, significantly, “target and switch off” pathways that allow cancers to grow.”

More: http://www.usnews.com/news/articles/2013/10/24/study-cannabis-compounds-can-kill-cancer-cells