Israeli-American Team Hopes to Cure Diabetes With Cannabis

Posted on April 29, 2015 by David

israel diabetes

“An American-Israeli biotech team is taking cannabis research to the next level by developing novel therapies using cannabis extract to treat diabetes, inflammatory conditions, chronic pain and cardiovascular disease.

ISA Scientific just signed a deal with Yissum, the technology-transfer company of the Hebrew University of Jerusalem, Hadasit, the technology-transfer company of the Hadassah Medical Organization in Jerusalem, and the Kennedy Trust for Rheumatology Research (KIR) in the United Kingdom to help bring the drugs to market.

All the credit for the idea, however, goes to a Hebrew University researcher who has worked on idea for years.

“Raphael Mechoulam deserves all the credit for this,” fellow researcher Chaim Lotan of Hadassah University Medical Center said.

Mechoulam discovered that cannabidiol (CBD) receptors existed not only in the brain but in other tissues found throughout the body.

Knowing this, he then went to work finding a way to alter cannabinoids to work on certain areas of the body.

“He synthesized a whole ‘family’ of cannabinoids, and therefore with some changes in molecular structure you can tailor cannabinoids to different receptors,” Lotan said.

Lotan, a cardiologist, helped work on making a drug for the heart.

“My role was only the cardiac part,” he explained “but we may see effects in other organs as well since we found so many receptors.”

The team is now ready for Phase 2 trials of the drug for diabetes and chronic pain and is hopeful that the drug, which has now psychoactive properties at all, will ultimately provide a solution that may not only manage diabetes but perhaps even cure the widespread disease.

“Unlike insulin and other existing medications for diabetes, CBD may actually suppress, reverse and perhaps cure the disease,” ISA Scientific Chief Executive Officer Mark J. Rosenfeld said. “So, the therapeutic alternatives offered by cannabis chemistry could go far in helping to resolve conditions responsible for a huge public health crisis in China and elsewhere.””

http://www.jspacenews.com/israeli-american-team-hopes-cure-diabetes-cannabis/

http://www.thctotalhealthcare.com/category/diabetes/

Medicinal Marijuana May Help Cure Children With Severe Epilepsy

Posted on April 22, 2015 by David

A marijuana plant

“Recent research found that a liquid form of therapeutic marijuana can provide cure to children with treatment-resistant epilepsy.

The said study will be presented at the American Academy of Neurology’s 67th Annual Meeting in Washington, DC in late April.”

http://au.ibtimes.com/medicinal-marijuana-may-help-cure-children-severe-epilepsy-1440398

http://www.thctotalhealthcare.com/category/epilepsy-2/

Promising cannabinoid-based therapies for Parkinson’s disease: motor symptoms to neuroprotection.

Posted on April 19, 2015 by David

“Parkinson’s disease (PD) is a slow insidious neurological disorder characterized by a loss of dopaminergic neurons in the midbrain. Although several recent preclinical advances have proposed to treat PD, there is hardly any clinically proved new therapeutic for its cure.

Increasing evidence suggests a prominent modulatory function of the cannabinoid signaling system in the basal ganglia. Hence, use of cannabinoids as a new therapeutic target has been recommended as a promising therapy for PD.

The elements of the endocannabinoid system are highly expressed in the neural circuit of basal ganglia wherein they bidirectionally interact with dopaminergic, glutamatergic, and GABAergic signaling systems.

As the cannabinoid signaling system undergoes a biphasic pattern of change during progression of PD, it explains the motor inhibition typically observed in patients with PD.

Cannabinoid agonists such as WIN-55,212-2 have been demonstrated experimentally as neuroprotective agents in PD, with respect to their ability to suppress excitotoxicity, glial activation, and oxidative injury that causes degeneration of dopaminergic neurons.

Additional benefits provided by cannabinoid related compounds including CE-178253, oleoylethanolamide, nabilone and HU-210 have been reported to possess efficacy against bradykinesia and levodopa-induced dyskinesia in PD.

Despite promising preclinical studies for PD, use of cannabinoids has not been studied extensively at the clinical level. In this review, we reassess the existing evidence suggesting involvement of the endocannabinoid system in the cause, symptomatology, and treatment of PD. We will try to identify future threads of research that will help in the understanding of the potential therapeutic benefits of the cannabinoid system for treating PD.”

http://www.ncbi.nlm.nih.gov/pubmed/25888232

“To conclude, development of safe, effective cannabis-based medicines targeting different mechanisms may have a significant impact in PD therapy.”

Full-text: http://www.molecularneurodegeneration.com/content/10/1/17

http://www.thctotalhealthcare.com/category/parkinsons-disease/

Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid.

Posted on October 2, 2014 by David

“Cannabigerol (CBG) is a safe non-psychotropic Cannabis-derived cannabinoid which interacts with specific targets involved in carcinogenesis…

Here, we investigated whether CBG protects against colon tumorigenesis.

In vivo, CBG inhibited the growth of xenograft tumors as well as chemically-induced colon carcinogenesis.

CBG hampers colon cancer progression in vivo and selectively inhibits the growth of colorectal cancer cells, an effect shared by other TRPM8 antagonists.

CBG should be considered translationally in colorectal cancer prevention and cure.”

http://www.ncbi.nlm.nih.gov/pubmed/25269802

http://www.thctotalhealthcare.com/category/colon-cancer/

Marijuana Better Cure for PTSD, Veteran Soldier Testifies

Posted on June 28, 2014 by David

“Veteran Matt Kahl has claimed that marijuana is the only drug that allows him to get over his PTSD, the side effect after two tours in the Afghanistan war.

Kbzk reported that in an interview with CBS News’ Barry Peterson (video below), Matt Kahl shared his experience with marijuana as a cure for his PTSD (post-traumatic stress disorder).

War veteran Matt Kahl came home to America after two tours in Afghanistan, a wounded soldier, physically and mentally. Kahl’s physical injuries wracked him with pain, and the mental anguish was overwhelming he had to take 15 different medications. The medication seemed short of helpful that Khal attempted suicide ten months after his return to America.

“About ten months after I got back, I attempted suicide. I was completely hopeless,” he said.

But then he discovered the “healing” effects of marijuana which had probably saved his life.

“Suddenly, my extremely overactive, hyper-vigilant mind started to calm down, and my pain gradually started to go away, too. I needed less of these other medications,” he revealed.

Shortly afterwards, Kahl was determined to move to another state where marijuana is legal so that he could “get his life back.” So he moved his family to Colorado.

Inquisitr reported that ever since the marijuana legalisation bill went into effect in Colorado, Denver’s crime rates have dropped by 10.6 percent compared to January of this year.

Matt Kahl now works with a support group called Grow4Vets in Colorado. He and other volunteers reportedly recently spent a day putting together bags of marijuana products to give away on holidays, like Memorial Day.

Current treatments of PTSD range from therapy to prescription drugs, but according to Grow4Vets founder Roger Martin, the group wants to replace the pills with marijuana.

“Anybody that’s been on narcotic medication especially wants to get off of it,” he said, adding that he really hasn’t met anybody who “just enjoys being in a drug stupor.”

Kbzk cited another veteran, marijuana shop owner Toni Fox’s father, who came home from Vietman suffering PTSD. Fox recalled her father struggled with PTSD his whole life that he eventually committed suicide when she was 14.

“I believe in my heart of hearts that, if he would have had access to cannabis, he would be alive today,” she said.

Despite Matt Kahl’s testimony, critics are still doubtful on the “healing” effects of marijuana, considering the fact that there is little or no scientific proof that it actually helps with PTSD.”

http://au.ibtimes.com/articles/557139/20140627/marijuana-cure-ptsd-matt-kahl.htm#.U64Y-5RX-uY

http://www.thctotalhealthcare.com/category/post-traumatic-stress-disorder-ptsd/

Sickle Cell Pain May be Managed with Cannabis

Posted on June 23, 2014 by David

“Can Medical Cannabis Help to Cure SCD?”

Sickle Cell Disease Pain May Be Managed 2

“Sickle cell disease (SCD) is a hereditary condition caused by a mutation in the haemoglobin gene, which leads to symptoms of anaemia, extreme pain, and organ damage if unmanaged.”

Sickle Cell Disease Pain May Be Managed 1

“Individuals suffering from SCD are far more likely to use cannabis than the general population, potentially for its analgesic properties.

In 2010, researchers at the University of Minnesota found that the synthetic THC analogue CP 55,940 was as effective as morphine sulphate in treating SCD-related severe pain in transgenic mice expressing human sickle haemoglobin, and that it was effective at smaller doses than the opioid.

In 2011, a further paper submitted by the same researchers to Blood (the Journal of the American Association of Hematology) indicated that CP 55,940 ameliorated severe pain associated with the hypoxia/reoxygenation cycle. CP 55,940 is a full agonist of both CB receptors, and is thought to act as an antagonist at the GPR55 receptor.

As well as this, cannabis has been repeatedly shown to act as a vasodilator, which could in itself assist in easing the blockages caused by build-up of sickle cells…

SCD is a painful and debilitating disease, and the overall inefficacy of opioid treatments and resultant poor quality of life for many sufferers is an indication that our approach to it is far from perfect.

If cannabis is a good candidate to replace opioids, it should be implemented forthwith to prevent ongoing suffering for existing patients.”

http://sensiseeds.com/en/blog/sickle-cell-pain-may-managed-cannabis/

Medical Marijuana Helps Cure Chronic Disease

Posted on June 21, 2014 by David

Medical Marijuana Helps Cure Chronic Disease

“The medicinal power of Marijuana is well documented throughtout history

Back in 2700 BC, According to Chinese lore, the Emperor Shen Nung, considered the Father of Chinese medicine, in 2700 BC ,discovered the healing properties of Marijuana as well as Ginseng and Ephedra.

Throughout recorded history, the use of Medical Marijuana has been linked to the ancient Egyptians, Persians, Greek civilizations, George Washington, Queen Victoria and even mainstream medicine by the 1840s.

From the 1850s to Y 1942, Marijuana was listed in the United States Pharmacopeia, an official public standards-setting authority for all prescription and over-the counter medicines, as a treatment for tetanus, cholera, rabies, dysentery, alcoholism, opiate addiction, convulsive disorders, insanity, excessive menstrual bleeding and many other health problems. My father was a Dental doctor and had a license to dispense the drug, pharmacies carried it back then.

During that same time frame prohibition gained popularity, that along with a growing “faith” in federal government.

By Y 1937, the United States passed its 1st federal law against Marijuana despite objections by the American Medical Association (AMA).

In fact, Dr. William C. Woodward, testifying on behalf of the AMA, told the US Congress:

“The American Medical Association knows of no evidence that Marijuana is a dangerous drug.”

He warned that a prohibition “loses sight of the fact that future investigation may show that there are substantial medical uses for Cannabis.”

Today, we see a growing trend of acceptance of Marijuana for its medicinal purposes.

Dr. Sanjay Gupta, CNN’s chief medical correspondent, reversed his Y 2009 opinion against Marijuana when he said, “We have been terribly and systematically misled for nearly 70 yrs in the United States, and I apologize for my own role in that.”

Now people including lawmakers are seeing the legalization of Marijuana in states like Colorado and Washington for “recreational” purposes. Most Americans are in favor of Medical Marijuana, and the legalization of this drug.

The Big Q: why does the federal government want to ban its usage?

The Big A: it is all about control and money, and there is a major market for it, plus it poses a major threat to the pharmaceutical industry.

Below are just a few of the many health benefits associated with Medical Marijuana:

1. It can stop HIV from spreading throughout the body.
2. It slows the progression of Alzheimer’s.
3. It slows the spread of cancer cells.
4. It is an active pain reliever.
5. It can prevent or help with opiate addiction.
6. It combats depression, anxiety and ADHD.
7. It can treat epilepsy and Tourette’s.
8. It can help with other neurological damage, such as concussions and strokes.
9. It can prevent blindness from glaucoma.
10. Its connected to lower insulin levels in diabetics.

Contrary to popular notions, many patients experience health benefits from Medical Marijuana without “getting stoned.””

http://www.livetradingnews.com/medical-marijuana-helps-cure-chronic-disease-55569.htm#.U6VjgZRX-uY

Shona Banda cured her terminal Crohn’s disease with cannabis

Posted on May 24, 2014 by David

Image result for shona banda

“Shona Banda was diagnosed with Crohn’s disease… She underwent several surgeries and was put on several pharmaceuticals, but her condition worsened progressively until she was considered terminal. She was bedridden… wasting away… She was waiting to die.

She managed to see Rick Simpson’s Run from the Cure…”

“RUN FROM THE CURE: The Rick Simpson Story – A Film by Christian Laurette” https://www.youtube.com/watch?v=aGjC4HReFL0

“Although she had been smoking marijuana to ease pain and help her sleep and eat, she had no way of making the oil, which required a pound of marijuana to produce the two ounces of cannabis oil she would need to heal.

Shona was in a funk about the lack of enough hemp to make her own oil when her husband noticed specks of oil residue in the inside of the vaporizer’s glass globe cover.

So she took the inhalation tube out of the vaporizer and sealed it, then simply collected those little blobs of oil from the inside of the glass globe with a spatula.

She did this three times a day, putting the collected oil residue into a capsule and taking it. After a very few days, Shona could walk without a cane. Soon she began eating and sleeping better and putting on weight. It wasn’t long before she was completely weened off all her pharmaceuticals.

She started a journal as she began getting better. The journal has become a book called Live Free or Die. The title is a reference to health freedom. Now she is very healthy and active.”

http://www.naturalnews.com/043718_chrons_disease_cannabis_shona_banda.html

“Crohn’s Disease Survivor Shona Banda Tells How Medical Marijuana Oil Helps Her “Live Free”” https://www.youtube.com/watch?v=x_otUB7pVMA

“Ben Swann Radio: Shona Banda Explains Her Remarkable Story On How Cannabis Oil Saved Her Life. After being diagnosed with Crohn’s disease in 2002, Shona Banda went through the struggles that many suffer with when battling the autoimmune disease. On the Ben Swann Radio Show, Ben and Shona discussed her tribulations while suffering from the disease and her immediate experiences after finding the cure to her disease.”
http://benswann.com/ben-swann-radio-shona-banda-explains-her-remarkable-story-on-how-cannabis-oil-saved-her-life/#ixzz32d6WqrPM

https://www.facebook.com/shona.banda

https://www.facebook.com/pages/Shona-Bandas-Live-Free-or-Die/146496222049591

http://www.thctotalhealthcare.com/category/crohns-disease/

Potential Cure for Epilepsy: Cannabis Vastly Reduces Seizures in Boy with Dravet Syndrome

Posted on May 23, 2014 by David

A judge checks on a marijuana sample during a judging session at Uruguay's second

“Scientists are looking at the potential use of cannabis to treat and potentially cure severe forms of epilepsy.

The medical benefits of medical marijuana for neurological conditions like epilepsy are highly debated.

Examining the potential use of the drug, a series of articles in the journal Epilepsia, a journal of the International League Against Epilepsy, looks at its potential use for treating the syndrome.

Edward Maa, from the Comprehensive Epilepsy Program at Denver Health in Denver, Colorado, looks at a case study of a child with Dravet syndrome – a very severe form of epilepsy.

In the case, a mother provided her child with a strain of medical marijuana high in Cannabidiol (CBD) and tetrahydrocannabinol (THC) known as Charlotte’s Web.

When used with the child’s normal drug regime, seizures dropped from 50 convulsions per day to just two or three per month.”

http://www.ibtimes.co.uk/potential-cure-epilepsy-cannabis-vastly-reduces-seizures-boy-dravet-syndrome-1449505

http://www.thctotalhealthcare.com/category/dravet-syndome/

Miracle Drug: Medical Marijuana Cures Child of Terminal Epilepsy

Posted on May 1, 2014 by David

Mia Wilkinson

“Only until recently has medical marijuana received its deserved accolades by the mainstream media as a miracle drug; however, many in the medical industry are still leaving pot on the back-burner….until NOW.

A Canadian mother named Sarah Wilkinson has tangible claims about how cannabis has saved her disabled and once terminally ill daughter’s life.”

During an interview with the Toronto Sun, Wilkinson said “I assumed people who wanted it just wanted to get high” prior to her daughter’s marijuana use. However, once administering marijuana to her daughter with no other options from the pharmaceutical industry, Mia’s seizures went from 100 a day to 8 at most, changing her stance about the drug overnight. Results upon using the herb were immediate. Mia’s seizures ended within 24 hours of using the herb and now the Wilkinson’s don’t hesitate to call the drug a miracle.”

http://www.prweb.com/releases/2014/05/prweb11808330.htm

“Medical marijuana gives epileptic child new lease on life” http://www.torontosun.com/2014/04/26/medical-marijuana-gives-epileptic-child-new-lease-on-life